Is the combination of phenibut and adaptol in treatment good?

Characteristics of Adaptol

This drug is classified as a tranquilizer. By influencing the functioning of the brain, it stimulates the production of the joy hormone, serotonin. The big advantage of the medicine is the absence of a hypnotic effect; adaptol can enhance the effect of sedatives. The medicine can be taken throughout the day.

• Adaptol is prescribed for a number of symptoms.
• Anxiety without meaningful motivation.
• Stressful conditions.
• Feeling of fear.
• Emotional stress.
• Neurotic conditions.

The effect of the drug has a beneficial effect on reducing anxiety during the process of quitting smoking.

Clinical trials have proven the effectiveness of adaptol in work that requires speed, logic and clarity of thinking. The drug improves attention and has a positive effect on performance. Treatment with the drug does not provoke excessive emotional activity.

The use of this drug is contraindicated in case of individual intolerance to the main substance Mebicar, during pregnancy and breastfeeding.

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10.07.2019 18:49:55

Expert: Zalman Rivlin

For stress and its consequences, the doctor may prescribe medications such as Phenibut and Adaptol. They have different composition and mechanism of action. We compared both tools to look at all their advantages and disadvantages.

The nootropic Phenibut contains aminophenylbutyric acid. It is produced in tablet and powder form by several companies - Organika, MirPharm, Ozon in the Russian Federation, Latvia, Belarus. It is available by prescription as it is an anxiolytic drug.

The compound in the drug is necessary for the normal functioning of the brain. Taking the drug improves the nutrition of nerve cells, normalizing the transmission of nerve signals. Phenibut promotes better communication between different parts of the cerebral cortex.

The drug has the following positive effects:

1. improves memory, memorization speed;
2. promotes clear consciousness;
3. reduces irritability and emotional excitability;
4. normalizes night sleep, increasing its quality and duration;
5. stimulates microcirculation;
6. is an antioxidant;
7. improves blood counts;
8. increases the resistance of the nervous system to stress;
9. prevents depression.

Phenibut differs from tranquilizers in that it not only calms the nervous system, but also increases brain activity, improving its functioning. Another difference is that there are much fewer side effects from its use. It does not reduce reaction and concentration.

Research and effectiveness

Phenibut has a psychostimulating and tranquilizing effect, relieves stress, anxiety, and irritability. It is used for anxiety and asthenic disorders. In pediatrics it is used for tics and stuttering.

According to some data, Phenibut with long-term use leads to dependence and withdrawal symptoms, but the risk of this is considered very low.

The drug improves the functional state of the brain by increasing the speed of blood flow and influencing the metabolic processes of tissues. It has antiplatelet, antioxidant and psychostimulating effects.

The action of the nootropic is as follows:

1. antihypoxic effect, which improves the energy state of neurons;
2. increased synthesis of proteins and RNA, which leads to activation of plastic processes in the nervous system;
3. acceleration of glucose excretion;
4. increased transmission of nerve impulses;
5. membrane stabilizing effect.

Sources:

1. Medicines. Mashkovsky M.D. 2012.
2. Encyclopedia of drugs. Radar. 2011.
3. Phenibut treatment for children. Rhythm Journal. 2020.

Side effects

The medicine is well tolerated with rare exceptions. Possible side effects include lethargy, headache, drowsiness, decreased blood pressure, and anxiety.

The following symptoms may appear:

1. dyspeptic manifestations;
2. allergy;
3. brokenness;
4. increased arousal of the nervous system.

A long course is addictive, and after stopping, withdrawal syndrome develops. It is not recommended to drive vehicles or operate complex machinery during therapy.

Dosage

The standard dosage for adults is 250 mg 3 times. The dose can be increased to 750 mg, maximum – 2500 mg, for the elderly – 1500 mg, for children – 300 mg per day.

Who is it suitable for?

Phenibut has a lot of indications:

1. decreased emotional activity;
2. Meniere's disease;
3. chronic stress;
4. chronic fatigue;
5. increased anxiety;
6. disorders of the vestibular apparatus;
7. circulatory disorders in the brain;
8. enuresis;
9. encephalopathy;
10. insomnia and other sleep disorders;
11. reactive emotional disorders;
12. logoneurosis;
13. obsessive states.

In pediatrics, Phenibut is used to treat tics and stuttering in children. It is also effective for claustrophobia, for preventing seasickness and reducing the severity of withdrawal symptoms in alcoholism. Previously, the drug was used to correct behavior at an early age.

Description of Adaptol

The anti-anxiety drug Adaptol is produced by Olainfarm in Latvia. Produced in tablet form. The main active ingredient is mebikar.

Positive effects of taking the medicine:

1. reduction of tension and irritability;
2. withdrawal relief;
3. normalization of sleep;
4. improvement of cognitive function.

It has tranquilizing activity without a hypnotic effect. Has a positive effect on the hypothalamus. Has a calming and nootropic effect. According to research, the drug increases the speed of thinking, logic and performance.

Cost and analogues

Which drug is better

Adaptol is a tranquilizer, Phenibut is a nootropic. The mechanism of action of the drugs is different. For adults, both drugs are suitable for indications, while children are more often prescribed Phenibut. The latter is also allowed for diseases of the liver and stomach, when Adaptol is contraindicated.

Phenibut has a milder and relatively weak effect, while Adaptol is stronger, but more often causes adverse reactions.

The doctor must choose the drug. Self-medication with Adaptol and Phenibut is unacceptable, as there is a risk of serious consequences, including drug dependence. You can only buy the products with a prescription, so you should first consult your doctor.

Source: https://expertology.ru/sravnivaem-fenibut-i-adaptol-opredelyaem-luchshiy/

Characteristics of Phenibut

The drug belongs to nootropics that improve the functioning of the central nervous system. The drug is prescribed for various symptoms.

• Memory loss.
• Insomnia.
• Stressful situations.
• Nervous exhaustion.
• Asthenic syndrome.
• Speech and movement disorders.
• To prevent motion sickness in transport.
• Strengthens the effects of sleeping pills, narcotics and neuroleptics.

The effect of the drug is useful for depression and conditions associated with excessive brain overstrain. The medicine is used in the treatment of nervous tics, stuttering, enuresis and other diseases that cause disruption of the transmission of nerve impulses to various organs.

Elderly people do not feel the relaxing effect of the drug. The medicine relieves lethargy and stimulates active activity.

If a child has problems with academic performance, attacks of unmotivated anxiety, or urinary disorders, taking phenibut will help cope with the problems.

It is contraindicated to prescribe the medicine for peptic ulcer disease and liver failure.

Drug therapy for PA

The following groups of medications will help stop panic attacks:

• Antidepressants. It is antidepressants that are designed to treat PA, and not only fight the symptoms. But the treatment is complex and lengthy; it is important to start with a small dose and gradually increase it to normal. Also, antidepressants should not be stopped abruptly; the dose must also be reduced gradually. The effect of treatment may occur no earlier than 3-4 weeks after the start of treatment. However, antidepressants do not guarantee complete relief from PA. PA may recur after treatment is discontinued.
• Tranquilizers. Therapy with tranquilizers should be episodic. Tranquilizers can overcome or prevent an attack. Among them, phenibut, adaptol, atarax will help fight insomnia and relieve nervous tension. Glycine is considered a “mild tranquilizer” due to its ability to make the patient’s behavior adequate.
• Beta blockers. They block the action of adrenaline, thereby preventing PA.

Medicines used for treatment

The fight against panic attacks will be easier if you adopt the following means:

Phenazepam is a tranquilizer, and one of the strongest. Phenazepam, thanks to its components, has a relaxing effect on the central nervous system, helps with insomnia and convulsions. Similar drugs are prescribed for phobic and hypochondriacal disorders. Phenazepam is very effective for the treatment of any disorders of the autonomic nervous system; it can overcome the symptoms of neurasthenia and irritability.

Tenoten is a homeopathic drug.

noten acts in several directions. Firstly, it calms, reduces anxiety and stress, and normalizes the psycho-emotional background. Secondly, it helps improve memory and enhance concentration. However, the drug does not have a sedative effect and can be used to treat children. Tenoten is prescribed for chronic prolonged stress, disorders of the autonomic nervous system, as well as for neurotic conditions.

Phenibut is a nootropic drug. Like any neurometabolic simulator, Phenibut has a beneficial effect on memory properties and stimulates mental activity. Drugs of this type improve cerebral circulation and normalize metabolic processes. Phenibut is prescribed for sleep disorders, memory loss and decreased performance, and in moments of severe mental stress. Phenibut is also effective for manifestations of causeless fear, anxiety and any other neurotic conditions.

Afobazole is a tranquilizer with a pronounced anxiolytic effect. Afobazole is not addictive (there is no negative reaction from the body after discontinuation of the drug). In addition, Afobazole does not have a sedative effect. The medicine helps to overcome insomnia, fear, including unfounded fear, irritability, timidity. Afobazole blocks feelings of anxiety, promotes relaxation, and actively relieves somatic and autonomic disorders. These tablets are prescribed for the treatment of anxiety disorders, neurasthenia, neurocirculatory dystonia, sleep disorders and other anxiety conditions.

Corvalol is a widely used combination drug. Corvalol is both an antispasmodic and a sedative. It is prescribed for neuroses, sleep disorders, hypertension, tachycardia, and spasms of the heart vessels. Corvalol is able to treat hypochondriacal syndrome and autonomic lability.

Anaprilin is a beta-blocker of general (non-selective) action. Anaprilin is prescribed for tachycardia, angina pectoris, tachyarrhythmia, arterial hypertension, pheochromocytoma. The product is effective for the prevention of migraines. Anaprilin eliminates the symptoms of myocardial ischemia, and due to its pronounced antiarrhythmic effect, it has a beneficial effect on the cardiovascular system and the central nervous system. The medicine helps prevent and cope with PA that has already begun.

Anaprilin has a wide range of contraindications and special instructions for use. It is better to take this medicine under the supervision of your doctor.

Glycine is a non-essential amino acid. Glycine is primarily a metabolic drug. Due to their pharmacological action, the tablets help to activate the processes of protective inhibition of the central nervous system. Glycine reduces vegetative-vascular disorders and reduces psycho-emotional stress. In addition, glycine helps to overcome the craving for alcohol, especially if you suddenly stop taking it [alcohol].

Glycine is indicated during severe mental stress (exams) or in other stressful situations (conflicts), with manifestations of VSD, with a tendency to panic attacks, with neurosis and sleep disorders.

Adaptol is a tranquilizer (anxiolytic) that helps eliminate feelings of fear, anxiety, and concern. Relieves emotional stress and irritability. Adaptol does not have a sedative effect, but it enhances the effect of taking sleeping pills. Adaptol is prescribed to treat emotional lability, reduce irritability, anxiety and other neurosis-like symptoms. Also, the use of the drug helps to cope with negative vegetative manifestations caused by hormonal instability (menopause, PMS).

If Glycine has a beneficial effect on the body when quitting alcohol, then Adaptol helps reduce the craving for smoking in case of nicotine addiction.

Atarax is a tranquilizer that helps improve the body's cognitive abilities. According to its pharmacological properties, Atarax is not a central nervous system depressant, but it has a strong sedative effect and is capable of partially inhibiting brain activity. Atarax is prescribed to relieve symptoms of anxiety (including relief of panic attacks). Atarax is also used to treat itching (symptomatically).

Only a doctor should decide how to get rid of panic attacks using these medications, and which drug to use. Self-medication is dangerous!

Pros and cons of taking medications

Drug treatment has a number of advantages:

• Quick help for panic attacks. Medicines can help you cope with an unexpected panic attack, and this is very important, especially if the attack occurs outside the home.
• Psychological comfort. Knowing that pills that can relieve a panic attack are at hand has a calming effect.
• Minimum costs. Antidepressants, tranquilizers or any sedatives help stop an attack quickly enough, and the drugs are relatively inexpensive.

Despite a number of advantages, drug treatment of PA also has a number of negative aspects:

• Any tablets have contraindications for use and a number of side effects.
• Medicines should not be mixed (use several different names of medicines), as their interaction can lead to irreversible health consequences.
• You should not use antidepressants or tranquilizers without consulting a specialist, especially if there is a need to take other medications (for chronic diseases).
• Drugs for the treatment of VSD and PA may be contraindicated during pregnancy and lactation.
• You should be aware that PA cannot be cured by simply taking a pill. Drugs only temporarily relieve symptoms and help relieve internal tension, but in 40% of cases, after stopping the drugs, a relapse occurs. A panic attack is, first of all, a psychological disorder and therapy should be comprehensive.

Source: myvsd.ru

Similarities and differences between the two drugs

Adaptol and Phenibut: what is the difference between these two drugs? Two drugs from different pharmacological groups provide different mechanisms of action on the body.

In some severe cases, doctors use the compatibility of Adaptol and Phenibut. Mutually enhancing the effect, the drugs work faster and more efficiently. The dosage of Adaptol and Phenibut is reduced together, as opposed to taking it separately. The interaction of the two drugs helps speed up the healing process.

How is it taken?

Both come in tablet form and are easy to store and easy to take.

Overdose

The instructions for Adaptol stipulate that the tablets can be taken regardless of the meal period. As a rule, patients are prescribed from 300 mg to 500 mg of the drug 2-3 times a day. The drug is prescribed for a period of 2 days to 3 months, depending on the diagnosis and characteristics of the course of the disease.

The drug is prescribed to children from the age of ten. Children are prescribed a dose of 300-500 mg three times a day. The treating specialist will tell you in detail about the treatment features.

Features of treatment with phenibut

It is drunk from 2-3 to 4-6 weeks. Repeated courses are prescribed after 2-4 weeks. The program begins with taking the full therapeutic dose, and should be completed gradually, accustoming the body to smaller doses of the medicine.

Off-course treatment is possible to prevent motion sickness. The tablets are taken 20 or 30 minutes before the trip. If symptoms of motion sickness have already appeared, then taking the drug is useless.

When Phenibut is taken together with anticonvulsants, the effect of both is enhanced, so it is better to reduce the dosage of both drugs.

Phenibut belongs to a group of drugs with a minimal level of toxicity. Its action is gentle, and the risk of side effects is minimal. The product is actively used to normalize the condition of young children and older people.

Mechanism of action and pharmacological effect

Side effects during treatment with Adaptol are rare in patients. Sometimes allergic manifestations are observed. When using high doses of the drug, the patient may experience dyspeptic disorders. In this case, treatment is suspended. In very rare cases, hypotension and hypothermia may occur. As a rule, these phenomena go away on their own.

The big advantage of the active ingredient Adaptol over others is the smaller number of side effects for VSD. According to reviews, Adaptol does not cause excessive stress or impair cognitive function.

Side effects indicated by the manufacturer and according to reviews:

• Excessive doses – short-term hypotension and hyperthermia, digestive problems.

Features of taking Adaptol

Phenibut and Adaptol, in comparison with other drugs, are considered equally safe and low-toxic. Unlike Phenibut, Adaptol should not be used to treat children and adolescents. Overdose may cause weakness, dizziness and low blood pressure.

If the use of the medicine causes an allergy, then you should stop taking the medicine and try to replace it with analogues.

The treatment regimen and types of medications should be selected by medical specialists based on the patient’s medical history and test results. It is impossible to say that Adaptol and Phenibut are analogue products that completely replicate the properties. Similar effects on symptoms are produced by different substances with different patterns of action. It is better to take medications together for quick and successful relief from disturbing disorders.

special instructions

The patient does not develop an addiction to the medicine, and no withdrawal syndrome is observed. During treatment, you can drive and perform activities that require increased attention. However, you need to be careful.

If blood pressure or body temperature decreases during therapy, there is no need to stop treatment. Gradually, temperature and blood pressure levels return to normal. If allergic reactions occur, treatment should be stopped.

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Teraligen: instructions for use, reviews, price, analogues, do you need a prescription?

Teraligen is a drug widely used in psychoneurological practice.
Dissolving in the patient’s blood, it suppresses the activity of certain centers of the brain.

The drug is used, among other things, in pediatrics and gerontology.

Radar

Teraligen is registered as a drug belonging to the group of neuroleptics (antipsychotic drugs).

It has a sedative (calming) effect on the nervous system.

Compound

Teraligen Valenta contains the main active ingredient – ​​alimemazine tartrate (1 tablet contains 5 mg of this compound).

Auxiliary components of the drug are talc, magnesium stearate, refined sugar, lactose, silicon dioxide.

Dissolving in the blood, alimemazine:

1. Stops vomiting.
2. Eliminates spasms.
3. Blocks the production of serotonin.
4. Has a calming effect on the nervous system.
5. Suppresses the production of histamine.

The active component is excreted from the body by the kidneys (up to 80% of the dose taken) within 2 days from the moment alimemazine enters the body.

Price

The drug Teraligen costs between 373-475 rubles. for 1 package of tablets (25-50 pcs.).

Injection solution is twice as expensive. In some pharmacies in Moscow it even reaches 904 rubles. for 1 package containing 10 ampoules of 5 mg/ml.

Do you need a prescription?

The main condition for dispensing the drug in question from pharmacies is a prescription from the attending physician.

To buy Teraligen in Moscow, you need to get a prescription from a neurologist or psychiatrist.

The drug belongs to the category of potent drugs. Therefore, it will not be possible to buy it without presenting a written prescription from a doctor.

Indications for use

The drug Teraligen is prescribed in case of development of:

1. Neuroses of various forms.
2. States of anxiety and excitement.
3. Depression, regardless of form and period of limitation.
4. A neuropsychiatric disorder that occurs due to problems with the condition of blood vessels.
5. Phobias, panic attacks.
6. Psycho-emotional instability developing as a result of brain injuries (regardless of their type or statute of limitations).
7. Obsessive thoughts.
8. Psychopathy.
9. Feelings of imaginary discomfort - physical or psycho-emotional.
10. A psychoneurological disorder that occurs as a result of infectious processes in the brain.

The drug Teraligen is prescribed for sleep disorders , regardless of the underlying cause of the disorder.

Due to its pronounced antipruritic and antihistamine properties, the medicine is used to relieve allergic reactions .

Instructions for use

Teraligen tablets are taken orally .

The drug is also used in the form of solutions; it is administered by intramuscular or intravenous injections .

The dosage and regimen of the drug depend on the purpose of prescribing the antipsychotic and the age of the patient.

• For adults, Teraligen is prescribed 5-10 mg/day, if the purpose of administering the drug is to provide a hypnotic effect; for psychotic conditions, 0.2-0.4 g/day.
• The drug is administered intramuscularly in the form of a 0.5% solution. For intravenous infusions of the drug, a starting dosage is used, not exceeding 25 mg with a further increase to 75-100 mg.

For children over 7 years of age, Teraligen is divided into 3-4 doses, equal dosages, the maximum daily volume is 25 mg.

The standard regimen for using the drug as a sleeping pill is 2.5-5 mg/day; to relieve an allergy attack, a neuroleptic is prescribed at 5-20 mg/day.

The optimal dosage of Teraligen prescribed to suppress psychopathic disorder should not exceed 60 mg/day.

When prescribing an antipsychotic to children, be sure to take into account not only the child’s age, but also body weight. This helps prevent the development of health complications.

Exceeding the prescribed dosage of the drug can lead to the development of multiple adverse effects on the body, including impaired consciousness.

The duration of the course of therapy depends on the type and stage of the psychoneurological disorder at the time of treatment, the patient’s age, and the presence of concomitant diseases.

While undergoing therapy with the antipsychotic Teraligen, activities that require increased concentration are contraindicated.

Side effects

Reviews from people taking Teraligen indicate that the drug is generally well tolerated by the body.

Potential side effects include:

• Psycho-emotional depression, craving for social isolation;
• Uncontrollable trembling in the arms and legs;
• General lethargy, decreased performance;
• Muscle weakness;
• Difficulty with bowel movements, predisposition to developing constipation;
• Urinary retention;
• Decrease in general body temperature;
• Epilepsy;
• Noise in ears;
• Yellowing of the sclera and skin;
• Suppression of physiological activity of the bone marrow;
• Increased density of bronchial secretion;
• Dizziness, increased heart rate;
• Nausea, unpleasant feeling in the stomach, loss of appetite;
• Increased dryness of the mucous membranes of the nasopharynx and oral cavity;
• Increased sweating.

Teraligen can also cause a decrease in blood pressure, headache, and a feeling of imaginary goosebumps on the body (paresthesia).

Direct limiting factors for the use of Teraligen:

• the presence of renal, liver or heart failure;
• hypertonic disease;
• tumor process in any part of the brain;
• blood clotting disorder (propensity to form blood clots, hemophilia).

Also, two conditions are contraindications for the use of the drug Teraligen - pregnancy and breastfeeding.

Alimemazine crosses the placental barrier and may harm a developing baby. In addition, the component is passed into breast milk in high concentrations.

Also, Teraligen cannot be used for diseases of the prostate gland (including the presence of prostate adenoma), and angle-closure glaucoma

Teraligen and alcohol: compatibility

While taking the medicine Teraligen, drinking alcohol contraindicated

Ethanol has a stimulating effect on the nervous system, while the purpose of using Teraligen is to provide a calming, relaxing effect.

The conflict between two types of biological mechanisms causes deterioration in well-being .

Reviews from patients who took the drug

Irina, 36 years old:

Pavel, 50 years old:

Ilona, ​​24 years old:

Reviews from doctors

Igor Nikolaevich, neurologist:

Yuri Petrovich, psychiatrist:

Roman Vladimirovich, psychotherapist:

Source: https://psihbolezni.ru/lechenie/teralidzhen-instruktsiya-po-primeneniyu-otzyvy-tsena-analogi-nuzhen-li-retsept/

Other indications

Grandaxin is effective not only for VSD, but also for neuroses, as well as other similar conditions. Indications include:

• alcohol withdrawal;
• premenstrual, menopausal period;
• mental maladjustment;
• mild depression;
• conditions accompanied by muscle asthenia and atrophy, when muscle relaxant anxiolytics are unacceptable for use.

The drug is a daytime tranquilizer. It does not cause addiction or withdrawal symptoms.

An important property of Grandaxin is the relief of panic attacks. This is a feeling that occurs suddenly or under the influence of a stressful situation. Accompanied by a strong feeling of fear and vegetative disorders.

The concepts of VSD and panic attack are closely related: the attack is a kind of exacerbation of neurocirculatory dystonia. Therefore, therapy for these conditions follows a similar plan.

Which is better: Atarax or Grandaxin

The drug Grandaxin is prescribed for the treatment of depression, stress, alcohol withdrawal syndrome, PMS, neuroses, and cardialgia. Tofisopam, the active component, exhibits its effect quite quickly, since the highest concentrations in the blood are recorded 2 hours after taking the pills.

Atarax is a tranquilizer with a milder effect, most often used for mild anxiety-depressive disorders. Grandaxin is much stronger in action and is used for moderate disorders. Indications for taking Grandaxin are more specific; before starting therapy, it will be necessary to assess the patient's condition and establish an accurate diagnosis; it is practically not prescribed for monotherapy.