The drug Phenazepam is a powerful anxiolytic drug, otherwise a tranquilizer. The active ingredient in it does not have a simple name - bromodihydrochlorophenylbenzodiazepine.
Thanks to its muscle relaxant and hypnotic effects, this medication became one of the most popular drugs of the 20th century in our country. In combination with the listed properties, the drug also relieves anxiety and increased excitability.
Doctors prescribe many sedative medications, including Phenazepam, for a long course of treatment, but do not explain to the patient what the compatibility of a particular drug with alcohol is and what the consequences of such an interaction may be.
Purpose of the drug Phenazepam
This medicine is very popular in the treatment of many diseases.
This medicine is very popular in the treatment of many diseases. The principle of its action is to slow down brain processes. For this reason, doctors prescribe the drug for the following symptoms:
- It is recommended to take fenozypam if the patient has an anxious, tense, irritable state;
- You can take pills if a person is diagnosed with vegetative-vascular dystonia;
- If a person feels dizzy or has pain in the head, then he should take the drug;
- Some types of epilepsy or regular seizure conditions are very often treated with Phenazepam;
- In the surgical field, it is used to relieve pain or put a person into an anesthesia state.
Attention! It is necessary to drink phenazepam with extreme caution, since it is possible to form an addiction, which is no different from the disease of drug addicts.
Medical staff are careful about the prescription, amount of the drug and duration of therapy, since all these criteria affect the human body. Plus, doctors categorically prohibit taking phenazepam with alcohol, because this combination is dangerous. You can only take the medicine for a hangover.
How to administer the antidote
Flumazenil is available in powder form. It is intended for intravenous administration. In case of poisoning, 0.3 mg of the drug is diluted in saline and the patient is given a drip. If necessary, the dosage is increased, carefully monitoring the patient's condition.
Is it possible to administer an antidote at home before the ambulance arrives? Doctors do not recommend doing this. It is not always the case that the person providing first aid is fluent in the technique of intravenous injections. Inept administration of the drug can cause harm to the victim.
In addition, it is not always possible to establish what exactly the patient was poisoned with, especially if the person is unconscious. Flumazenil has contraindications that only a doctor can take into account. Therefore, using the Phenazepam antidote at home is extremely undesirable. It can only be administered in a hospital under the supervision of a specialist.
Contraindications to taking the medication
It is not recommended to take the drug if you are depressed
In order to know how to take and when you can use the drug Phenazepam, you need to familiarize yourself with the main contraindications to taking the medicine:
- It is not recommended to take the drug in a state of depression;
- If you have been diagnosed with glaucoma;
- With obvious signs of dysfunction of human organs, such as the liver and kidneys;
- If there is poisoning with tranquilizers or neuroleptics of any complexity;
- In the presence of intoxication with sleeping pills;
- People with drug addiction should not take medications.
Attention! Under no circumstances should Phenazipam be mixed with alcoholic beverages.
Stages of poisoning
Overdose occurs with impaired respiratory function. There are 4 stages of Phenazepam poisoning in total. :
- Lung
- Moderate
- Heavy
- Chronic
Mild overdose
The people around you will most likely not even see that there is something wrong with the person. Because he can contact them without any problems. But still, a person who has mild poisoning with the drug feels very tired and sleepy. He may experience tinnitus. Everything gets by with the person falling asleep deeply or being in a state of mild drug intoxication. The pupils continue to respond normally.
Combination of phenazepam and alcoholic beverages
If you ignore the warnings of doctors, you can come to an unpleasant result.
When taking the drug, it is very important to know what will happen to the human body when combined with alcoholic beverages. Everyone knows the fact that both drugs have negative effects on health. Especially on the brain. It is worth considering that this combination enhances a number of negative consequences that may arise. The central nervous system is especially affected, due to violations of which many situations can be complicated.
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Attention! Symptoms manifest themselves individually in each person, since each body has its own characteristics.
If you ignore the warnings of doctors, you can come to an unpleasant result. Therefore, phenazepam with alcohol should be taken wisely and with caution. Therefore, do not risk your health.
Description of the tranquilizer
"Phenazepam" is a tranquilizer from the group of benzodiazepines. This is a pretty powerful drug. In terms of the strength of its effect on the body, it surpasses many other similar drugs.
The active component of the tranquilizer (phenazepam) binds to special benzodiazepine receptors in the body. This promotes better absorption of chlorine ions by nerve cells and a decrease in neuron excitability.
A person’s anxiety and irritability disappear, and mental calm occurs. Sleep becomes deep and sound. In addition, the drug relaxes muscles and eliminates cramps.
The main consequences of taking the drug and alcohol
A person who takes phenazepam and alcohol should be careful, as there can be many consequences
A person who takes phenazepam and alcohol should be careful, as there can be many consequences. In this section, we will try to find out how scary this combination is. Among the most common negative symptoms are the following:
- The person may feel very dizzy;
- Very often, a citizen taking a drug with alcohol may experience weakness and impaired coordination of movements;
- Phenozepam tablets very often cause a gag reflex and hallucinations after ethanol;
- Very often, such people have a decrease in hemoglobin in the blood.
Attention! It is very important to know about all possible negative consequences in order to protect yourself from negative consequences and even death.
A drinker must exclude alcohol from his diet while taking the drug, as the risk of suffocation increases. The combination of two substances constitutes a lethal dose for the body. By the way, very often many people commit suicide with just such a cocktail. If the suicide is saved, his stomach is washed out. It is worth noting that only a small percentage is saved.
Another risk group is people who regularly abuse alcohol after taking phenazepam. A large number of alcoholics specifically take medication to enhance the effects of ethanol on the body and achieve intoxication as quickly as possible. If you use substances this way, addiction will not take long to develop. Sooner or later, alcohol and medicine will lead to an overdose. In such situations, side effects manifest themselves in the following symptoms:
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- The pressure indicator decreases;
- Tachycardia develops;
- The combination of alcohol and phenazepam reviews, which confirm this, leads to disruption of the functioning of the kidneys and genitourinary system;
- Hallucinations are very common;
- Digestive problems, such as constipation or diarrhea;
- The most dangerous consequence is death.
Overdose, addiction, harm to the body
For outpatient treatment (at home), Phenazepam is taken 0.25–0.5 mg 2–3 times a day. Under the supervision of a doctor in a hospital, the dosage can be increased to 5–10 mg per day. Such measures are taken for effect as a last resort - for example, in the treatment of epilepsy.
- excessive sleepiness;
- prolonged confusion;
- decreased reflexes;
- long-term dysarthria;
- muscle tremors;
- bradycardia (low heart rate, pulse about 30–50 beats per minute);
- shortness of breath, disruption of the respiratory cycle;
- decreased blood pressure;
- coma.
Taking Phenazepam, even in permitted doses, may be accompanied by side effects:
- regular feeling of fatigue;
- deterioration of concentration, attention and memory;
- partial or complete disorientation;
- difficulty in motor and mental reactions;
- headaches;
- increased depression;
- asthenic syndrome;
- dysarthria (speech disorder);
- dizziness;
- ataxia (motility disorder, expressed in inconsistency of movements of different muscle groups);
- unbalanced gait;
- confusion;
- euphoric state.
Disturbances in the functioning of the cardiovascular system and changes in the biochemical composition of the blood are often observed. Long-term use of Phenazepam can provoke:
- leukopenia and agronulocytosis - a decrease in the level of leukocytes in the blood;
- thrombocytopenia – decreased platelet count, deterioration of coagulation;
- neutropenia – a decrease in the number of neutrophils, reducing the body’s resistance to bacteria and fungi;
- tachycardia – increased heart rate;
- anemia – decreased levels of hemoglobin and red blood cells.
Taking the drug and hangover
It is worth considering that it is not recommended to take the medicine even with a hangover
If you use the drug with alcohol, the worst can happen. In order to know how dangerous this is, you should familiarize yourself with the rules for combining them. After all, everyone knows that the drug is popular in the fight against alcoholism. So, if you drink alcohol after Phenazepam, it can lead to the following consequences:
- If the level of ethanol in the blood is higher than the standard value, then the effect on the central nervous system increases. The most dangerous consequence is the onset of phenozepan sleep, in which a gag reflex occurs, depressed breathing, crash syndrome are observed, in some situations the heart stops, the person receives amnesia, defecation or urination, etc.
- Those who take it quickly become accustomed to the drug with alcohol. A person becomes dependent and even abstinence forms. Any instructions prescribe contraindications for this combination, since attacks of epilepsy, rage, and nightmares may occur.
Attention! It is worth considering that it is not recommended to take the medicine even with a hangover. The body still contains a concentration of ethanol, so when the substances come into contact, complicated symptoms occur.
- If a person experiences changes in the central nervous system, then it is strictly forbidden to drink alcoholic beverages. Most often these are elderly people, teenagers, those who take cannabinoids, and people with metabolic hereditary changes. In such situations, inappropriate symptoms and reactions may appear. For example, mental destabilization and hallucinations may occur. Plus, such people very often get used to it.
- If you take the drug during a hangover, then an effective syndrome is observed afterward. Performance decreases significantly, irritability and muscle weakness appear. All the hangover symptoms get worse.
Side effects when taking Phenazepam with alcohol
During a hangover, alcohol remains in the blood, which, in combination with Phenazepam, acts in an unpredictable way. A person may suddenly be overtaken by an irresistible thirst for action.
He is ready to communicate with the whole world, rush to solve problems anywhere on the planet. However, sociability and friendliness can develop into aggression and outbursts of rage at any moment.
During a hangover, alcohol remains in the blood, which, in combination with Phenazepam, acts in an unpredictable way. A person may suddenly be overtaken by an irresistible thirst for action
The presence of alcohol in the blood enhances the effect of Phenazepam, causing an exaggerated response from the nervous system. Instead of a relaxing sleep, a person can fall into a phenazepam sleep - a condition that threatens cardiac arrest, suppression of the respiratory reflex, vomiting, and memory impairment.
After such a dream, a person not only feels bad. He feels cotton-like weakness, muscle flaccidity throughout the body, the sufferer’s pulse quickens, and the temperature rises.
Taking Phenazepam for a hangover can cause an acute attack of unmotivated aggression, frightening hallucinations, nightmares, and an increased level of anxiety in elderly people, adolescents, drug addicts, and alcoholics.
Phenazepam with a hangover aggravates the course of chronic diseases of the liver, gastrointestinal tract, and respiratory organs. The patient develops symptoms such as dizziness, coordination disorders, inhibition of muscle reactions, and mental activity.
The need for timely stopping
If a person has beer alcoholism, then the dose of the drug should not exceed 5 mg per day, and the treatment course should not last more than 5 days
How many serious consequences are observed in people who neglect the ban on taking the drug and alcoholic beverages. Particularly severe symptoms occur with beer alcoholism. The fact is that intoxicating drinks contain an agonist for MDD. This component calms the effect of beer, however, it also slows down and complicates the treatment. For this reason, doctors set certain limits for the duration of therapy, beyond which it is prohibited.
Attention! If a person has beer alcoholism, then the dose of the drug should not exceed 5 mg per day, and the treatment course should not last more than 5 days. Otherwise, it threatens to form an addiction.
Why do doctors not recommend combining Phenazepam and alcoholic drinks? The main reason is the effect of both substances on the human nervous system. If they act simultaneously, this threatens to increase all side effects. Taking the drug and alcohol causes severe intoxication, which in some cases leads to death. Think about it, is it worth it?
In modern medicine, the simultaneous use of medication and alcohol is considered one of the most risky and unpredictable combinations. The extent of the consequences is almost impossible to predict. For this reason, you should not ignore the warning in the instructions.
Combination rules
You should wait until the end of treatment and wait at least 36 hours until the medicine is eliminated from the body in order to drink alcohol without causing harm to health or negatively affecting the effect of therapy. The period of alcohol withdrawal depends on the strength and volume of alcohol consumed, the weight and height of the person. The patient weighing 60 kg requires the most time. For example, after drinking 100 ml of cognac (42%) you should wait up to 30 hours, after 100 ml of beer (4%) - 3 hours.
In case of alcohol intoxication, before starting treatment, the patient is given a detoxification drip to remove the breakdown product of ethanol, acetaldehyde. In other situations, they wait until the body copes with the described task on its own.
To eliminate withdrawal symptoms, the patient is prescribed 1–5 tablets per day (1–5 mg) or 500 mcg intramuscularly 2 times a day. The maximum daily dose is 9 mg. The course of therapy is 2 weeks. The short period is due to the high risk of a person developing drug dependence.
special instructions
Instructions for use of Phenazepam injections and tablets contain a warning about taking them with alcohol. Without directly indicating possible consequences.
In order to prevent suicide, the section on a possible lethal dose was removed from it. It is believed that death occurs when taking 10 mg of the drug simultaneously (one tablet contains up to 1 mg). It has been established that the damaging effect of each tablet is enhanced by at least 3 ml of absolute medical alcohol.
Based on this, we can say that death can occur if one tablet is mixed with 200 ml of beer for an hour. The same result will occur from medicine taken in a state of severe alcoholic hangover.
The drug is often used to treat alcohol addiction. With this therapy, patients experience a long-term withdrawal syndrome, especially if beer alcoholism. Reviews about this therapy are mixed; a decision on prescribing the drug must be made by a narcologist.
Historical facts
The drug was invented in the 1970s. The developers who received the state order for the new medicine were the scientific directors of the departments of pharmacology from the Odessa Institute of Physics and Chemistry. After successful research and launch of the drug on the market, the group of voters received the USSR State Prize.
The peak use of the drug came at the end of the 80s, when facts of abuse of barbiturates were published and proven. Phenazepam and its analogues have become alternative drugs with similar effects but fewer adverse reactions.
First aid
The first aid procedure is determined by the specific stage of poisoning. The main thing is to get the patient to a medical facility as soon as possible.
If the patient is conscious, a gastric lavage procedure is performed. Salt water with activated carbon is used as a washing liquid. Patients are given a saline laxative and given an enema to cleanse the intestines.
If the patient is unconscious, gastric lavage is performed exclusively after the airway intubation procedure.
Let's summarize
Unfortunately, you can die from Phenazepam if you do not follow your doctor's recommendations. The use of the drug will not lead to death unless you increase the dose yourself and do not mix the drug with substances that mutually enhance the effect of the drug. Remember that only 10 mg of the active substance of the drug per day is the minimum lethal dosage. If you listen to your doctor, it will be impossible to die from Phenazepam. Don't self-medicate!
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Phenazepam is one of the most powerful tranquilizers of the benzodiazepine series. It is used in the treatment of hypochondriacal conditions, phobias, panic attacks, psychoses, neuroses, insomnia, alcoholic delirium, and convulsive syndrome. Treatment with Phenazepam is carried out exclusively as prescribed by a doctor and under his supervision, since unsystematic use of the drug can cause serious complications, one of which is an overdose.
Further treatment
After a gastric lavage procedure, a patient with an overdose is given a special substance to neutralize the effect of Phenazepam. Doctors focus on the patient’s general well-being, the functionality of the cardiovascular system, and breathing patterns. If necessary, a blood test is performed to determine the amount of the drug in the serum.
Medicines related to the group of benzodiazepines are neutralized through the use of Anexat or Flumazenil. This substance has a short-term effect and suppresses the effects of Phenazepam.
In case of Phenazepam poisoning, a patient must be given a drip with saline solution with the addition of 0.2 mg of Anexat for 30 seconds so that 3-5 mg of the substance is injected. In patients with a high risk of epileptic seizures, such an antidote may cause a negative reaction in the body.
Often, special symptomatic drugs are used that are necessary to maintain the normal functionality of the cardiovascular system, as well as the respiratory tract, and substances that stimulate the activity of the central nervous system.