Comparison of the effectiveness of Mebikar and Adaptol
The effectiveness of Mebicar is quite similar to Adaptol - this means that the ability of the drug substance to provide the maximum possible effect is similar.
For example, if the therapeutic effect of Mebicar is more pronounced, then using Adaptol even in large doses will not achieve this effect.
Also, the speed of therapy - an indicator of the speed of therapeutic action - is approximately the same for Mebicar and Adaptol. And bioavailability, that is, the amount of a drug reaching its site of action in the body, is similar. The higher the bioavailability, the less it will be lost during absorption and use by the body.
Adaptol
The main substance in Adaptol is mebicar (which has the same name as the drug Mebicar). Its structure is similar to that of metabolites. In essence, we are talking about vital molecules produced in all cells of the body (proteins, lipids, carbohydrates, nucleic acids).
The drug is able to act on the hypothalamus, thus eliminating the feeling of anxiety, unreasonable fear, and panic attack.
Adaptol eliminates nicotine withdrawal. This term refers to the consequences of quitting smoking, which entails an endless desire to smoke, irritation and “withdrawal.”
As a rule, such a process becomes protracted, difficult, and secondary for the smoker and his body. When a person abruptly abandons his habit, that is, the system to which the body is accustomed, this causes a number of disturbances in internal processes. The supply of these harmful substances disappears, and the dependent person’s body feels discomfort. The nervous system is the first to make itself felt. The same manifestation occurs with alcohol addiction.
In this case, Adaptol slows down and calms the functioning of the nervous system. We can say that the effect of the drug has a sedative and hypnotic effect on the body. Adaptol can also be taken by children with restrictions over the age of 10 years.
Adaptol is taken orally, regardless of food intake, 500 mg 3 times a day. Dosage may vary depending on the case of the disease and its stage.
It does not reduce mental and motor activity, so Adaptol can be used during the working day or school. It does not affect the emotional background, only the general condition.
It does not have a hypnotic effect, but enhances the effect of sleeping pills and improves natural sleep processes.
Adaptol improves cognitive functions, attention and mental performance. The medicine is dispensed to people who have digestive system disorders associated with an emotional background.
Comparison of safety of Mebicar and Adaptol
The safety of a drug includes many factors.
At the same time, in Mebicar it is quite similar to Adaptol. It is important where the drug is metabolized: drugs are excreted from the body either unchanged or in the form of products of their biochemical transformations. Metabolism occurs spontaneously, but most often involves major organs such as the liver, kidneys, lungs, skin, brain and others. When assessing metabolism in Mebicar, as well as in Adaptol, we look at which organ is the metabolizing organ and how critical the effect on it is.
The risk-benefit ratio is when the prescription of a drug is undesirable, but justified under certain conditions and circumstances, with the obligatory observance of caution in use. At the same time, Mebicar does not have any risks when used, just like Adaptol.
Also, when calculating safety, it is taken into account whether only allergic reactions occur or possible dysfunction of the main organs. In other matters, as well as the reversibility of the consequences of using Mebicar and Adaptol.
Mebikar: instructions for use, price, reviews, analogues and substitutes
Mebicar tablets have a wide range of applications in psychiatry.
The Russian drug belongs to the group of nootropic, anxiolytic, and stress-protective drugs. Unlike most analogues, this tranquilizer has a minimum of contraindications and in rare cases causes adverse reactions.
Approved for long-term use, therapy can last up to 6 months.
INN
It has the International nonproprietary name Tetramethyltetraazobicyclooctanedione.
Compound
The composition is based on the substance of the same name, mebicar.
It promotes:
- improving oxygen supply to myocardial tissue;
- normalization of disturbed electrolyte blood balance, as well as the content of potassium ions in myocardial cells, erythrocytes, and blood plasma;
- increasing cellular energy resources;
- improving protein synthesis;
- normalizing sleep, improving its quality, reducing the frequency of night awakenings;
- removal or relief of nicotine withdrawal;
- stabilization of the psycho-emotional background.
Mebicare contains calcium stearate and povidone as auxiliary components.
In the form of the drug under the name Mebikar IS , produced by the Odessa pharmaceutical company, it additionally contains methylcellulose.
Price
20 tranquilizer tablets can be purchased for an average of 240 rubles .
To purchase the medicine, you need a prescription in Latin from a neurologist.
Prescription restrictions
It is prohibited to prescribe tablets if you have an individual intolerance to the components of the composition, as well as in the first trimester of pregnancy.
At the discretion of the doctor, a tranquilizer can be prescribed to pregnant women from the second trimester.
Possible negative reactions
Taking a tranquilizer may be accompanied by the following negative reactions:
- development of an allergy to the drug;
- lowering blood pressure;
- increased body temperature;
- stomach and intestinal disorders.
Experts note that surges in pressure and body temperature are short-term phenomena, do not require discontinuation of Mebicar therapy and normalize on their own. These symptoms do not require special treatment.
Overdose symptoms
If you take increased doses of a tranquilizer, there is a high probability of overdose, which is characterized by the appearance of adverse reactions that occur in a more acute form.
It is urgent to perform gastric lavage and induce vomiting by any available means.
If necessary, the specialist prescribes symptomatic therapy.
Instructions for use
The drug is taken orally, the tablets must be taken with plenty of liquid.
There are no strict requirements for the period of taking the medicine, but doctors do not recommend taking the pills on an empty stomach.
The duration of therapy also depends on the problem the patient has.
For severe mental disorders, the treatment period can last up to six months. In milder cases, a course of taking Mebicar can last from several days to 3 months.
Reviews from patients who took the drug
How effective and safe are Mebicar tablets, say patients who have completed the course of therapy:
Veronica, 28 years old, Chelyabinsk: After the birth of the child, I fell into some kind of depressive state. It persisted for a long time, so I was forced to turn to a specialist. He prescribed me a two-month course of Mebicar tablets.
I took a tablet in the morning and in the evening. The doctor warned that the drug has a cumulative effect, that is, it takes time to feel a positive result. I began to notice changes after 5-6 days.
My mood improved significantly, the negative thoughts that tormented me were replaced by a positive attitude towards life. After completing a full course of therapy, I was finally able to fully enjoy my new role as a mother.
Separately, I would like to note that I took the pills while breastfeeding my baby. The therapy was carried out under the supervision of a specialist; no pathologies or deterioration in the child’s condition were identified.
Artem, 39 years old, Armavir: With the help of Mebikar, he struggled with his long-term addiction – smoking. I decided to get rid of the addiction on my own after the doctor discovered that I had heart problems.
Quitting smoking was not accompanied by any special means; it depended only on willpower and the desire for a healthy lifestyle. However, I regularly felt the urge to smoke a cigarette.
As a result, I turned to a neurologist and talked about my problem. The specialist recommended that I take Mebicar tablets for three months. Initially, I did not feel any changes, but gradually the craving for smoking began to disappear. The nervousness and irritability associated with quitting smoking were eliminated. My head became clear and I felt like a new person.
A couple of years have passed since then; during this period I have not smoked a single cigarette. An excellent result, certainly achieved with the help of Mebikar.
Nadezhda, 31 years old, St. Petersburg:
Due to problems at work, serious problems with nerves began. Various phobias, nervousness, anger, and aggressiveness became my constant companions. A neurologist diagnosed me with a severe neurotic disorder.
As therapy, I was prescribed Mebicar tablets. I drank them for quite a long time, almost 5 months. The treatment was accompanied by periodic intestinal disorders and pressure surges. But the drug managed to cope with my main problem.
In general, reviews about Mebicare are positive. Experts note that adverse reactions were observed in no more than 20% of patients. In 98% of cases, therapy has a positive result.
Analogs
Among the wide pharmacy range you can find analogues and substitutes for Mebicar. These drugs have different compositions, but are similar in their effect on the body and indications for use.
The following drugs are most similar to Mebicar:
- Adaptol;
- Phenibut;
- Nootropil;
- Afobazole.
Among the presented analogues, only Afobazole is released for free sale; the rest of the presented substitutes are sold strictly according to the prescription from a neurologist.
Mebicar or Adaptol: which is better?
Adaptol is one of the most popular tranquilizers. And at the same time it is very similar to Mebikar.
The drugs are analogues of each other and can be interchangeable in the treatment of mental pathologies.
However, tranquilizers have several differences:
- The two drugs are based on the substance mebicar. But in Adaptol its concentration is higher (0.5 mg in each tablet, Mebicare contains 0.3 mg).
- The two tranquilizers have a significant difference in cost - 20 Mebicar tablets can be purchased for 240 rubles, a similar number of Adaptol tablets can be bought in Moscow for an average of 700 rubles.
It is quite difficult to make an unambiguous conclusion about which of the two drugs is better. This is due to the fact that each drug reveals its pharmacological properties differently in the body.
When a doctor prescribes one of the drugs, it is strictly not recommended to replace it with an analogue! Despite the similar composition, the body may react poorly to a substitute for the prescribed drug.
Mebicar is a reliable Russian drug belonging to the group of tranquilizers, nootropics, and stress-protective drugs.
It has a wide range of applications, is marked by a minimum of contraindications, and is occasionally accompanied by adverse reactions.
Prohibited for use in self-medication; specialist supervision is required.
➤
Source: https://psihbolezni.ru/lechenie/mebikar-instruktsiya-po-primeneniyu-tsena-otzyvy-analogi-i-zameniteli/
Comparison of addiction between Mebicar and Adaptol
Like safety, addiction also involves many factors that must be considered when evaluating a drug.
So, the totality of the values of such parameters as “o syndrome” in Mebicar is quite similar to the similar values in Adaptol. Withdrawal syndrome is a pathological condition that occurs after the cessation of intake of addictive or dependent substances into the body. And resistance is understood as initial immunity to a drug; in this it differs from addiction, when immunity to a drug develops over a certain period of time. The presence of resistance can only be stated if an attempt has been made to increase the dose of the drug to the maximum possible. At the same time, Mebicar has quite a small amount of “syndrome”, just like Adaptol.
Indications
The following indications for the use of mebicar are registered[5]:
- for neuroses and neurosis-like conditions occurring with symptoms of irritability, emotional excitability, anxiety, fear (in particular, in patients with alcoholism in remission);
- hypomanic and anxiety-delusional states without psychomotor agitation and serious behavioral disorders (including schizophrenia, involutional and vascular psychoses);
- residual effects after acute psychosis with symptoms of emotional instability, productive symptoms;
- chronic verbal hallucinosis of organic origin;
- in complex therapy of nicotine withdrawal syndrome.
Can be used in combination with antipsychotics and other tranquilizers.
Comparison of side effects of Mebicar and Adaptol
Side effects or adverse events are any adverse medical event that occurs in a subject after administration of a drug.
Mebicar has more side effects than Adaptol. This implies that the frequency of their occurrence is low in Mebicar and low in Adaptol. Frequency of manifestation is an indicator of how many cases of an undesirable effect from treatment are possible and registered. The undesirable effect on the body, the strength of influence and the toxic effect of drugs are different: how quickly the body recovers after taking it and whether it recovers at all. When using Mebicar, the body's ability to recover faster is higher than that of Adaptol.
Adaptol or Mebicar – which is better? Reviews
Opinions of people who took Adaptol:
- Unlike other tranquilizers, Adaptol does not cause drowsiness. Since I drive all the time, this is very important to me. And it’s almost impossible to do without sedatives in a modern metropolis;
- Good medicine that works quickly. I was never able to quit smoking, but I definitely became calmer;
- It's a little expensive to drink Adaptol. This is especially felt when you need to achieve consolidation of the effect, and for consolidation the course takes 2–4 weeks. At first, my head became cloudy and there was a bitter taste in my mouth.
Reviews about Mebicare:
- There are few contraindications, almost no side effects, it works quickly and well. It only tastes very bitter, but for this you do not need to chew it, but immediately swallow it;
- I tried to take Mebicar to improve my sleep, but it didn’t help me. Maybe my reason for poor sleep is something else, but it didn’t help my husband either;
- A good drug that helped restore peace of mind after moving to a new job.
Comparison of ease of use of Mebicar and Adaptol
This includes dose selection taking into account various conditions and frequency of doses. At the same time, it is important not to forget about the release form of the drug; it is also important to take it into account when making an assessment.
The ease of use of Mebicar is approximately the same as Adaptol. However, they are not convenient enough to use.
The drug ratings were compiled by experienced pharmacists who studied international research. The report is generated automatically.
Last update date: 2019-09-19 05:59:53
Mebicar analogues and prices
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All Mebicar analogues are presented for informational purposes only and are not a reason for making an independent decision about replacing the drug. Before using the drug, consult your doctor and read the instructions for use.
SELF-MEDICATION CAN BE HARMFUL TO YOUR HEALTH
Source: https://www.poisklekarstv.com/mebikar/analogi
Effect of the drug
Adaptol tablets, representing a group of anxiolytic (anti-anxiety) drugs, provide a tranquilizing effect on the central nervous system. When treated with medication, there are no changes in motor functions, muscle relaxation (muscle relaxation), or a decrease in mental activity.
The drug is called a daytime tranquilizer because it does not cause drowsiness. Pharmacological properties:
- removes the feeling of internal fear, panic attacks;
- relieves irritability and increased excitability;
- eliminates emotional stress;
- exhibits an antioxidant effect under stress of various origins;
- affects the emotiogenic zones of the hypothalamus and the 4 main neurotransmitters, ensuring their balance and integration;
- activates cognitive (mental) functions;
- stimulates intellectual activity;
- improves mental activity and attention.
The medication potentiates the therapeutic effect of hypnotics. When administered orally, the bioavailability of tablets is 80%. The drug component mebicar, after penetration into the blood, partially binds to red blood cells, the rest remains in a free state. Metabolized in the liver. Excreted by the kidneys, urine and through the intestines. With long-term use, it does not accumulate in tissues.
Similar remedies in other forms
There are similar Tofisopam products on the pharmaceutical market, which are manufactured in other dosage forms.
Oxylidine
The tranquilizer is manufactured in the form of a parenteral solution and tablets with the main component - benzoclidine hydrochloride.
The main instructions for prescribing medication are related to disturbances in cerebral blood microcirculation, which leads to the development of such diseases of a neurotic and mental nature:
- depression and anxiety;
- psychopathy and neuropathy;
- cyclothymia;
- hypertension of cerebral etiology and cardiac pathologies.
It is prohibited to use the drug if you are allergic to the composition of the medication and with renal failure, as well as with myasthenia gravis, liver dysfunction and low blood pressure. The medicine is not prescribed during pregnancy, breastfeeding and in childhood.
Orally prescribed 3-6 tablets per day with a dosage frequency of 2-3 times. The solution is administered parenterally intravenously or subcutaneously 1-2 ml twice a day. The doctor may increase the dosage to 4-6 ml per day.
To relieve a hypertensive crisis, the drug is first administered parenterally, followed by a transition to the oral form. The therapeutic course of treatment for mental illness is 3-4 months.
Negative actions:
- dyspepsia;
- skin allergies - itching, urticaria and hyperthermia;
- polyuria;
- a sharp decrease in blood pressure.
Sibazon
Sibazon is produced in solution for injection and in tablets with the active ingredient - diazepam. It is used by dermatologists to treat allergic itching, as well as in psychiatry and neurology for depressive, aggressive, and anxiety conditions. Sibazon is often prescribed for the treatment of epilepsy and relief of alcohol withdrawal syndrome.
Not used in therapy for:
- sensitivity to the drug composition;
- alcohol, drug and drug intoxication;
- myasthenia gravis;
- respiratory depression;
- glaucoma;
- renal, cardiac and liver failure.
The solution is not administered to children under 1 month, and tablets are not used until 6 months, and are also not prescribed in the 1st and 3rd trimesters of pregnancy and lactation.
Tablets should be taken 3 times a day, 5-15 mg. The parenteral solution is used intravenously using a dropper or stream, as well as intramuscularly in 1-2 ml doses. The frequency of administration per day is 1-3 times.
Dosages depend on the patient’s age, the diagnosed pathology and the degree of its progression and are set by the doctor individually for each patient.
Side symptoms:
- dyspepsia;
- headache, insomnia and fatigue;
- dermatitis and bronchospasms;
- dizziness and depression.
Diazepam
This is a tranquilizer based on the main ingredient - diazepam. The medicine is produced in tablets and parenteral solution. Diazepam is used in the treatment of neurological and mental etiology of diseases, as well as in case of improper functionality of the vestibular apparatus.
Diazepam is prescribed for:
- neuroses with anxiety, hysteria and irritability;
- hypochondria and neurasthenia;
- psychosis and depression;
- insomnia;
- alcohol withdrawal symptoms.
Also prescribed in combination with other medications for:
- brain injury;
- spasms in muscle fibers and brain vessels;
- arthrosis, rheumatism, bursitis;
- myositis and polyarthritis;
- hypertension and unstable angina;
- Meniere's pathology.
Do not use the medication for:
- sensitivity to ingredients;
- myasthenia gravis and epileptic seizures;
- alcoholism and drug addiction;
- paranoid and suicidal thoughts;
- apnea;
- kidney, myocardial and liver dysfunction;
- glaucoma;
- hepatitis, ataxia and porphyria.
Do not use in the treatment of children under 3 years of age, women in the 1st and 3rd trimester of pregnancy and during pregnancy.
The dosage for pathologies of psychoneurotic origin is 2-15 mg per day. In gynecology, Diazepam is used 2.5-10 mg two to four times a day. Relief of withdrawal syndrome - 10 mg 3-4 doses per day.
Negative actions:
- hives;
- weakness in muscle fibers;
- ataxia, depression and insomnia;
- lethargy, hallucinations and dizziness;
- dyspepsia.
Seduxen
It is an anticonvulsant and tranquilizing drug with an antipruritic effect. The active ingredient in the drug is diazepam. The medicine is produced in a parenteral solution.
The drug is prescribed for:
- nervousness and psychosis;
- anxiety syndrome;
- depression;
- psychomotor overexcitation;
- brain diseases;
- epileptic seizures;
- spasms and cramps in muscle tissue;
- dizziness and migraine pain;
- nervous tics, vomiting and enuresis in children and adolescents.
Do not use the medication for:
- sensitivity to components;
- myasthenia gravis;
- drug addiction and alcoholism;
- glaucoma.
Seduxen is not taken during pregnancy in the 1st trimester and lactation, as well as children under 6 years of age. In tablets, 2.5-5 mg is prescribed 1-2 times a day with a gradual increase to 10 mg. For epilepsy and neurological pathologies using a dropper - 10-30 mg.
Negative manifestations:
- drowsiness, lethargy;
- dizziness;
- ataxia;
- dyspepsia;
- dermatological allergy.
Relanium
Relanium is an analogue of Tofisopam with the active ingredient - diazepam. The medicine is produced in solution for injection and in tablets.
A tranquilizer is prescribed for:
- epilepsy and seizures;
- psychomotor agitation;
- disturbances in cerebral microcirculation;
- tetanus;
- alcohol syndrome.
Also used in the treatment of hypertension, cardiac arrhythmia and menstrual irregularities.
It is not recommended to use the medication for:
- allergies to components;
- myasthenia gravis;
- alcohol, medication and drug addiction;
- apnea;
- liver/kidney failure.
Women in the 1st and 3rd trimesters of pregnancy are not prescribed Relanium, as well as during lactation, and in children under 3 years of age.
To relieve an attack of psychosis and neurosis, 10-20 mg is administered parenterally. In case of severe disorders, the solution is administered at intervals of 4 hours. When the condition stabilizes, the patient is transferred to an oral form of treatment.
Negative symptoms:
- insomnia or drowsiness;
- dizziness, confusion, depression and hallucinations;
- dyspepsia;
- decreased blood pressure and tachycardia;
- swelling;
- skin rashes and severe itching.
See also:
TOP 12 analogues of Nootropil - substitutes by mechanism of action
Adaptol® (500 mg)
One tablet contains
active substance – mebicar 500 mg,
excipients: methylcellulose, calcium stearate.
Description
Tablets are white or almost white, flat-cylindrical in shape, with a chamfer and a score on one side.
Pharmacotherapeutic group
Other anxiolyticsATC code N05BX
Pharmacological properties
Pharmacokinetics
When the drug is administered orally, 77-80% of the taken dose of mebicar enters the blood, up to 40% of which is bound by erythrocytes.
The rest of the mebicar does not bind to blood plasma proteins and is found in the plasma in a free form, is freely distributed throughout the body and freely overcomes cell membranes.
The maximum concentration of mebicar in the blood is reached 0.5 hours after taking the drug and the high level remains for 3-4 hours, then gradually decreases. Mebicar is completely excreted from the body in urine and feces within 24 hours.
The drug does not undergo biochemical transformations and does not accumulate in the body.
Pharmacodynamics
Adaptol has moderate tranquilizing activity, eliminates or weakens restlessness, anxiety, fear, internal emotional tension and irritability.
Adaptol acts on the activity of structures included in the limbic-reticular complex, in particular, on the emotiogenic zones of the hypothalamus, and also has an effect on all 4 main neurotransmitter systems - GABA, cholinergic, serotonergic and adrenergic, promoting their balance and integration, does not have peripheral adrenergic effects actions.
The tranquilizing effect of the drug is not accompanied by muscle relaxation and impaired coordination of movements. On this basis, adaptol is called a “daytime tranquilizer.” It does not have a hypnotic effect, but enhances the effect of sleeping pills and improves sleep in case of sleep disturbances. Adaptol eases or relieves nicotine withdrawal.
Indications for use
- neuroses and neurosis-like conditions occurring with symptoms of irritability, emotional instability, anxiety and fear
- to improve the tolerability of neuroleptics and tranquilizers in order to eliminate the somatovegetative and neurological side effects they cause
- for cardialgia of various origins (not related to ischemic
heart disease)
– as a means of reducing the desire to smoke tobacco, as part of complex therapy
Directions for use and doses
adaptol is taken orally, regardless of food intake, 250-500 mg 2-3 times a day. The maximum single dose is 3 g, the daily dose is 10 g. The duration of the course of treatment is from several days to 2-3 months.
In complex therapy, as a means of reducing the desire to smoke tobacco, the drug is prescribed at 500–1000 mg 3 times a day for 5-6 weeks.
Addiction, addiction and withdrawal syndrome to Adaptol have not been established. If the next dose has not been taken, continue the course of treatment at the previously prescribed doses. If necessary, you should consult your doctor.
Side effects
- allergic reactions (skin rashes, itching)
- dyspeptic symptoms (heartburn, belching, feeling of fullness in the abdomen, diarrhea)
- hypotension, decreased body temperature
- weakness, dizziness
Adaptol is usually well tolerated. These side effects may occur after using high doses. In this case, you should stop taking the drug.
Contraindications
– hypersensitivity to the active substance or to
excipients
– pregnancy and lactation period
- children and teenagers up to 18 years of age
Drug interactions
adaptol can be combined with antipsychotics, tranquilizers (benzodiazepines), hypnotics, antidepressants and psychostimulants.
special instructions
In cases of hypotension and/or decreased body temperature (body temperature may drop by 1-1.5 °C), discontinuation of the drug is not required. Blood pressure and body temperature normalize on their own within a few days.
Features of the influence on the ability to drive a vehicle or potentially dangerous mechanisms
Should not be used during work by vehicle drivers and people whose profession involves increased concentration of attention.
Overdose
The toxicity of the drug is low. There is no typical clinical picture of an overdose. No cases of severe poisoning have been recorded.
Symptoms: weakness, hypotension, dizziness may occur.
Treatment: symptomatic treatment, including gastric lavage.
Release form and packaging
10 tablets each in a blister pack made of polyvinyl chloride film and aluminum foil.
2 contour packages along with instructions for medical use in the state and Russian languages in a cardboard pack.
Storage conditions
Store in a dry place, protected from light, at a temperature not exceeding
25 °C.
Keep out of the reach of children.
Shelf life
4 years
The drug should not be used after the expiration date indicated on the package.
Manufacturer
JSC “OLINEFARM”.
Address: st. Rupnitsa 5, Olaine, LV – 2114, Latvia.
Registration Certificate Holder
JSC "OLINEFARM"
Address: st. Rupnicu 5, Olaine, LV-2114, Latvia.
Address of the organization receiving claims from consumers regarding product quality in the territory of the Republic of Kazakhstan:
050009 Almaty, Abay Ave. 151/115, office 807,
phone/fax 007,
Adaptol reviews
Anantavati: 4 80 reviews Sedasen forte: 2 7 reviews Bifren: 2.1 55 reviews Motherwort forte: 4.1 14 reviews Persen Knight: 4.
7 31 reviews Persen: 4.4 116 reviews Vitango: 5 2 reviews Melaxen: 3.6 56 reviews Alora: 2.
4 11 reviews Sedans: 5 2 reviews
Adaptol prices in pharmacies
- 325.36 UAH. ADAPTOL tablet. 500 mg 20 Olainfarm JSC (Latvia, Olaine)
- 208.65 UAH. Adaptol caps. 300 mg blister No. 20
- 228 UAH ADAPTOL tablet. 300 mg No. 20
- 139.45 UAH. Adaptol caps. 300 mg No. 20(10x2)
- 206.18 UAH. ADAPTOL caps. 300 mg each No. 20 (10x2)
More prices for Adaptol Prices for Adaptol are provided by the service Search for drugs in pharmacies of Ukraine Anantavati: 4 80 reviews Sedasen forte: 2 7 reviews Bifren: 2.1 55 reviews Motherwort forte: 4.1 14 reviews Persen Knight: 4.7 31 reviews Persen: 4.4 116 reviews Vitango: 5 2 reviews Melaxen: 3.6 56 reviews Alora: 2.
4 11 reviews Sedans: 5 2 reviews
Adaptol prices in pharmacies
- 206.18 UAH. ADAPTOL caps. 300 mg each No. 20 (10x2)
- 309.98 UAH. ADAPTOL tablet. 0.5 g, No. 20
- 228 UAH ADAPTOL tablet. 300 mg No. 20
- 459.4 UAH. ADAPTOL capsules 300 mg No. 20 (10x2)
- 208.65 UAH. Adaptol caps. 300 mg blister No. 20
- 325.36 UAH. ADAPTOL tablet. 500 mg 20 Olainfarm JSC (Latvia, Olaine)
More prices for Adaptol Prices for Adaptol provided by the service Search for medicines in pharmacies in Ukraine
Page 3
Anantavati: 4 80 reviews Sedasen forte: 2 7 reviews Bifren: 2.1 55 reviews Motherwort forte: 4.1 14 reviews Persen Knight: 4.
7 31 reviews Persen: 4.4 116 reviews Vitango: 5 2 reviews Melaxen: 3.6 56 reviews Alora: 2.
4 11 reviews Sedans: 5 2 reviews
Adaptol prices in pharmacies
- 325.36 UAH. ADAPTOL tablet. 500 mg 20 Olainfarm JSC (Latvia, Olaine)
- 459.4 UAH. ADAPTOL capsules 300 mg No. 20 (10x2)
- 201.02 UAH. ADAPTOL caps. 300 mg No. 20
- 228 UAH ADAPTOL tablet. 300 mg No. 20
- 206.18 UAH. ADAPTOL caps. 300 mg each No. 20 (10x2)
More prices for Adaptol Prices for Adaptol provided by the service Search for medicines in pharmacies in Ukraine
Page 4
Anantavati: 4 80 reviews Sedasen forte: 2 7 reviews Bifren: 2.1 55 reviews Motherwort forte: 4.1 14 reviews Persen Knight: 4.
7 31 reviews Persen: 4.4 116 reviews Vitango: 5 2 reviews Melaxen: 3.6 56 reviews Alora: 2.
4 11 reviews Sedans: 5 2 reviews
Adaptol prices in pharmacies
- 459.4 UAH. ADAPTOL capsules 300 mg No. 20 (10x2)
- 631 UAH ADAPTOL tablets 500 mg No. 20 (10x2)
- 191.17 UAH. Adaptol caps 300 mg N20
- 240.5 UAH. Adaptol 300 mg capsules No. 20
- 92.06 UAH Adaptol tab 300 mg No. 10
- 325.36 UAH. ADAPTOL tablet. 500 mg 20 Olainfarm JSC (Latvia, Olaine)
More prices for Adaptol Prices for Adaptol provided by the service Search for medicines in pharmacies in Ukraine
Page 5
Anantavati: 4 80 reviews Sedasen forte: 2 7 reviews Bifren: 2.1 55 reviews Motherwort forte: 4.1 14 reviews Persen Knight: 4.
7 31 reviews Persen: 4.4 116 reviews Vitango: 5 2 reviews Melaxen: 3.6 56 reviews Alora: 2.
4 11 reviews Sedans: 5 2 reviews
Adaptol prices in pharmacies
- 240.5 UAH. Adaptol 300 mg capsules No. 20
- 346.5 UAH. Adaptol 0.5 g tablets No. 20
- 208.65 UAH. Adaptol caps. 300 mg blister No. 20
- 206.18 UAH. ADAPTOL caps. 300 mg each No. 20 (10x2)
- 325.36 UAH. ADAPTOL tablet. 500 mg 20 Olainfarm JSC (Latvia, Olaine)
- 228 UAH ADAPTOL tablet. 300 mg No. 20
More prices for Adaptol Prices for Adaptol provided by the service Search for medicines in pharmacies in Ukraine
Page 6
Anantavati: 4 80 reviews Sedasen forte: 2 7 reviews Bifren: 2.1 55 reviews Motherwort forte: 4.1 14 reviews Persen Knight: 4.
7 31 reviews Persen: 4.4 116 reviews Vitango: 5 2 reviews Melaxen: 3.6 56 reviews Alora: 2.
4 11 reviews Sedans: 5 2 reviews
Adaptol prices in pharmacies
- 228 UAH ADAPTOL tablet. 300 mg No. 20
- 284 UAH ADAPTOL caps. 300 mg No. 20
- 391 UAH ADAPTOL tablet. 500 mg No. 20
- 459.4 UAH. ADAPTOL capsules 300 mg No. 20 (10x2)
- 240.5 UAH. Adaptol 300 mg capsules No. 20
- 191.17 UAH. Adaptol caps 300 mg N20
- 201.02 UAH. ADAPTOL caps. 300 mg No. 20
More prices for Adaptol Prices for Adaptol provided by the service Search for medicines in pharmacies in Ukraine
Cheap domestic analogues
Price matters in modern life; everyone wants to cut costs, especially when it comes to treatment. Sometimes, the cost of the prescribed course is beyond the financial capabilities of the patient.
In such cases, it is worth taking a closer look at more affordable domestic drugs (mainly Russian and Ukrainian) with similar effects, since cheap analogues of Adaptol are present on the market in large quantities:
- Phensitate (tablets), the most profitable analogue of domestically produced Adaptol, is from the same pharmacological subgroup, although it differs from the original drug in the main active ingredient and costs less from 86 rubles.
- Phenazepam (tablets) has a pronounced anxiolytic, sedative, anticonvulsant effect. Prescribed for sleep disorders, psychoses and other diseases of the nervous system. The price depends on the dosage of the active substance, ranging from 500 mg (from 90 rubles); 1000 mg (from 112 rubles).
- Anvifen (capsules), based on the active ingredient – aminophenylbutyric acids hydrochloride. Two types of dosage are possible: 50 mg (from 149 rubles) to 250 mg (from 249 rubles). Prescribed for insomnia, Meniere's disease, stuttering, dizziness.
- Mebicar (tablets) is an anxiolytic, stress-protective, nootropic drug. Taking the medicine does not depend on the timing of meals. Price from 280 rubles
- Aralia tincture , a product of plant origin, is used as a central nervous system stimulant. Increases overall tone, improves appetite, normalizes sleep, helps cope with fatigue, and stimulates the processes of the nervous system. The price varies from 38 rubles.
Precautionary measures
Should not be used during work by vehicle drivers and people whose profession involves increased concentration of attention[5].
Side effects
When taking Mebicar, allergic reactions (itching of the skin) are possible. In such cases, it is necessary to discontinue the drug. There may be a decrease in blood pressure (hypotension) and hypothermia (a decrease in body temperature by 1-1.5 °C), which usually normalize on their own. There are also drowsiness, weakness, dizziness, and dyspeptic symptoms.[5]
Adaptol tablets instructions - indications for use - side effects - reviews
Sedatives are a group of psychotropic substances that are often prescribed to patients with various pathologies, both mental and somatic. The most effective sedatives are tranquilizers. Their use is limited by a large number of contraindications and side effects. The exception is adaptol, a drug that has a mild sedative effect.
Release form
The manufacturer produces the drug in the form of tablets and capsules. The dosage of capsules is always 300 mg, the dosage of tablets can be 300 or 500 mg of active ingredient. Adaptol is the trade name of a drug patented by Olainfarm. Country of origin: Latvia. The international name for the drug is mebikar .
Pharmacological group
The group of a medication is determined by its belonging to a particular type of drug. Mebicar belongs to the group of psychotropic substances, namely tranquilizers. In this case, the medicine is a so-called “daytime” tranquilizer, which has a moderate sedative effect.
Instructions for use
Adaptol is taken twice or thrice a day, regardless of meals. The dose of the drug is not titrated, the average therapeutic dosage is prescribed immediately. Adults take 300 or 500 mg 2-3 times a day at the same time. Teenagers - 250 mg twice a day.
Adaptol does not accumulate in the body, its effect is noticeable immediately after the start of administration. In some cases, a few days of treatment are sufficient.
Treatment is allowed for a maximum of 2-3 months. The maximum dose taken at one time should not exceed 3000 mg.
To treat nicotine addiction, the concentration is increased. It is recommended to take 500-1000 mg of the drug three times a day for 1.5 months. During the course of treatment, it is not recommended to drive vehicles or engage in activities that require increased concentration.
Analogs
You can replace the drug with drugs that have the same or similar mechanism of action. The following medications are analogues of adaptol in composition:
- Mebicar;
- Mebix;
- Mebicar-IC;
- Mebikar-Tathimpharm.
The last of the listed drugs is a Russian analogue and is produced in Kazan. The advantage of Russian-made Mebikar is its relatively low cost.
Spectrum of action
In terms of its chemical composition, the drug is close to natural components produced by the body. The main point of action of the drug is the limbic-reticular complex. In addition, according to the instructions, Adaptol tablets affect four mediator systems:
- serotonin;
- adrenalin;
- cholinergic system;
- gamma-aminobutyric acid.
The medication does not have a peripheral blocking effect, namely, it does not lower blood pressure due to the process of relaxation of the muscle layer of the vascular wall.
According to reviews from patients who took Adaptol, the drug instantly eliminates anxiety signs, irritability, anxiety, and emotional stress. At the same time, bringing the emotional background back to normal is not accompanied by a failure in coordination of movements, as well as muscle relaxation.
“Adaptol” does not reduce mental activity, and also does not affect motor coordination indicators. Because of this, the drug can be used by both students and working citizens.
This tranquilizer does not provoke a feeling of euphoria or unreasonable joy in the patient.
The active substance in monotherapy does not have a hypnotic effect, but when taken simultaneously with other sedative medications, it reduces their effect.
Constant use of the medication can completely eliminate or greatly alleviate the symptoms of nicotine abstinence.
According to the instructions and reviews from doctors, “Adaptol” increases attention and performance.
After a single dose of the drug, the active substance is absorbed in the digestive system by eighty percent. In this case, the maximum content of the active microelement in the blood is recorded after thirty minutes and persists for four hours.
About half of the taken dosage of the drug binds to red blood cells, the rest is in a free state.
At what age is it allowed to take it?
According to the instructions for use, it is not recommended to take the drug before the age of eighteen. This is due to the lack of information about children's reactions to this medicine. But many doctors allow the use of this drug in pediatrics if there are grounds for such a prescription.
Moreover, the minimum age of a patient who is prescribed Adaptol is usually from nine to ten years.
Even experienced doctors do not recommend the medicine for children aged eight, six or younger, because the reaction to the medicine in children can be unpredictable.
For example, taking “Adaptol” before bed together with antipsychotics can cause apnea, which threatens the baby’s life at night.
In addition, the child’s kidneys or liver may not be able to cope with this drug. And although the drug has excellent tolerability, the likelihood of negative manifestations before the age of ten years is very high. If “Adaptol” was prescribed by an experienced pediatrician, then any reactions of the child’s body will be under his control.
“Adaptol”: compatibility
The drug can be used as part of complex treatment with other tranquilizers, as well as antipsychotics and antidepressants.
Negative reactions
In most cases, therapy with the drug “Adaptol” is well tolerated, due to the fact that the main microelement is close to natural molecules (in its chemical structure), present in all cells of the body and necessary for life.
In addition, it is important to be careful when using the drug “Adaptol” if a person has chronic liver and kidney diseases or low blood pressure.
You should not drink alcohol while taking medication. This combination can cause a drop in blood pressure (even to the point of fainting), as well as the appearance of heaviness in the head.
There is evidence that after drinking strong drinks while taking the drug Adaptol, problems developed in the functioning of the central nervous system, which were manifested by loss of orientation in space and memory disorders.
Combined use of Adaptol with alcoholic beverages can lead to vegetative-vascular dystonia and panic attacks. In rare situations, alcohol provokes neutralization of the effects of the drug. From the above, we can conclude that it is better not to drink alcohol during therapy with Adaptol.
Side effects of Adaptol are rarely recorded. Sometimes the following symptoms may appear:
- Allergic reactions.
- Dizziness.
- Bronchospasm (pathology that occurs when the muscles of the bronchi are activated and their lumen is reduced).
- Weakness.
- A decrease in body temperature below the standard (thirty-five degrees).
- Skin itching.
- Reduced arterial blood pressure.
- Malfunctions of the gastrointestinal tract.
Peculiarities
Sometimes, when using the drug, side effects (“Adaptol”) occur; body temperature may drop below the standard. At the same time, you should not stop stopping therapy, since this phenomenon disappears after a few days without the use of complex treatment. “Adaptol” is not addictive or addictive.
When conducting therapy, you should avoid work that requires increased attention. “Adaptol” is sold in pharmacies only with a prescription from the attending physician.
Unlike other substitute drugs, the medicine does not have a hypnotic effect. Thanks to this property, the use of “Adaptol” is allowed during the day.
“Adaptol”: analogues
Like any other drug, Adaptol has substitutes, for example:
- “Mebix.”
- Alprazolam.
- “Elzepam.”
- "Gidazepam".
- "Afobazole".
- “Phenazepam.”
- "Elenium".
- “Phenibut.”
- “Strezam.”
- “Noofen.”
- "Sibazon".
- “Tenoten.”
- "Anvifen".
- "Mebicar".
- “Amizil.”
- "Grandaxin".
The cost of “Adaptol” is 500 rubles.
Which remedy is more effective – “Adaptol” or “Afobazol”?
In addition to Adaptol, there are medications on the therapeutic market with a different chemical composition, but with a similar spectrum of action. These medications include Afobazol, which can be purchased at pharmacies without a doctor’s prescription. The main effect of Afobazole is an anti-anxiety effect along with a stimulant.
At the same time, “Afobazol” does not have a pronounced sedative and hypnotic effect. The medication is effective in that it does not provoke withdrawal symptoms and does not affect memory and attention. In terms of the severity of the therapeutic effect, these two drugs are approximately at the same level.
In addition, these medications require a course of treatment and are practically ineffective as emergency medications.
As for the harmful effects, they occur quite rarely with both drugs, mainly when the doses recommended by the doctor are not followed. Otherwise, the drugs are well tolerated, even with prolonged treatment.
Since medications with an anxiolytic effect are taken only as prescribed by a medical specialist, the choice of medication depends on the doctor’s recommendations.