The drug Cavinton and its analogues. Cavinton Comforte: instructions for use and differences from analogues
Cinnarizine is an analogue of Cavinton in tablets. It refers to drugs that act as a blocker for calcium slow channels. It is also used to reduce blood viscosity, increase tissue stability and as a vasodilator.
Who is Cinnarizine contraindicated for?
The instructions for use state that the Cavinton analogue should not be taken in the following cases:
- in children under 12 years of age;
- in case of individual intolerance to the components of the drug;
- period of breastfeeding and pregnancy;
- with galactosemia.
Side effects
Reviews from patients indicate that the drug most often causes such abnormalities as decreased blood pressure, skin rashes, weight gain, headaches, depression or disorientation. Each side effect occurs depending on the individual characteristics of the body.
Drug interactions
Interactions with other drugs include the following:
- when taking the antihypertensive drug Methyldopa at the same time, it increases the hypotensive effect, which requires monitoring blood pressure in patients;
- complex treatment with beta-blockers, diuretics (Clopamide, hydrochlorothiazide), hypoglycemic agents (glibenclamide), cardiac glycosides (digoxin), anticoagulants (acenocoumarol), tricyclic antidepressants (imipramine) did not reveal any interaction between these drugs.
Despite the possibility of combination with many groups of drugs, when taking Cavinton, it is recommended to exercise caution when simultaneously prescribing other drugs that inhibit the activity of the blood coagulation system and are intended for the treatment of arrhythmia.
What is the difference between Cavinton and Vinpocetine
The difference between these drugs is the different drug manufacturers. Cavinton is made in Hungary and is more expensive than Vinpocetine. Vinpocetine is manufactured in the Russian Federation, so it costs less. A doctor must prescribe medications. Both medications have the same properties.
Vinpocetine is manufactured in the Russian Federation, so it costs less.
Some patients believe that Cavinton is more effective because it is manufactured abroad, and when the product is manufactured in Russia, production technology may be violated. But clinical studies do not support this point of view.
Price
Cavinton in tablets of 5 mg in an amount of 50 pcs. costs 240 rubles. 10 ampoules of the product cost 320 rubles. Vinpocetine is cheaper. Tablets 5 mg 50 pcs. cost about 100 rubles. 10 ampoules are sold for 60 rubles.
Analogs
- Bravinton;
- Vero-Vinpocetine;
- Winpoton;
- Vinpocetine;
- Vinpocetine forte;
- Vincetin;
- Cavinton forte;
- Telektol.
When choosing analogues, it is important to understand that the instructions for use of Cavinton, the price and reviews of drugs with similar effects do not apply.
It is important to consult a doctor and not change the drug yourself.
Which is better Cavinton or Vinpocetine?
The drugs are absolutely identical. However, Cavinton is considered to be safer than Vinpocetine due to better alkaloid clearance.
Ukrainian substitutes
Ukrainian-made drugs provide worthy competition to Russian drugs. The list below presents the best analogues of Cavinton from Ukrainian pharmacological concerns, with vinpocetine as the main component.
- Vinpocetine Astrapharm . The medicine is available in tablets. Prescribed for conditions resulting in circulatory failure in the head, vascular pathology in ophthalmology, idiopathic tinnitus, Meniere's disease. Contraindications: coronary heart disease, arrhythmia, pregnancy, lactation, childhood. The average price is 55–70 rubles.
- Vinpocetine Darnitsa . Psychostimulant, nootropic medication. Release form: tablets, solution for injections. Indications for use: cerebrovascular pathologies, vascular disorders of the retina and mucous membrane of the eyes, senile hearing loss, Meniere's disease, idiopathic tinnitus. The average price is 50–65 rubles.
Tanakan
Tanakan is used by doctors to treat patients with peripheral and cerebral circulation disorders. The active substance of the drug is a plant component that affects the metabolic processes occurring in cells, as well as the vasomotility of blood vessels.
For which diseases should it be used?
Tanakan is actively fighting the following diseases:
- disturbances of visual functions of vascular origin;
- decreased visual acuity;
- neurosensory deficits of various forms;
- Alzheimer's disease;
- Raynaud's disease;
- extraneous noise in the ears;
- dizziness.
special instructions
Before you start taking Cavinton tablets, you must carefully read the instructions for the drug. There are a few special instructions that you should pay attention to, these include:
- The presence of changes in the electrocardiogram in the form of prolongation of the QT interval requires periodic monitoring of the functional activity of the heart.
- One Cavinton tablet contains about 41 mg of lactose, which must be taken into account by persons with impaired breakdown and absorption of carbohydrates.
- Fructose intolerance is grounds for discontinuation of the drug.
- The drug does not affect the speed of psychomotor reactions and the ability to concentrate.
Contraindications and precautions
These include:
- Hemorrhagic stroke in the acute stage
- Severe coronary heart disease
- Severe cardiac arrhythmia
- Phenylketonuria
- Periods of pregnancy and breastfeeding
- Minors under 18 years of age
- Intolerance or excessive hypersensitivity to the components of the medication.
Cross-drug interactions
Methyldopa in combination enhances the hypotensive effect, so you need to monitor your blood pressure. Should be taken with caution with anticoagulants and antiarrhythmic drugs.
Side effects
Sides of the visual organs: rarely - swelling of the optic nerve head, even less often - redness of the conjunctival sac.
Immune system: rarely – hypersensitivity to the drug.
CNS: euphoria, insomnia, depression.
Heart: ischemia, arrhythmia, increased blood pressure.
Gastrointestinal tract: diarrhea, abdominal pain.
Other: allergies, rash, hives, weakness, feeling of heat in the body.
Overdose
There is no specific data, but if there is suspicion, then symptomatic treatment with mandatory gastric lavage is needed.
Trental
Analogues of Cavinton Forte have one more drug in their portfolio - this is Trental. It is available in tablet form and as a solution in injection ampoules. The drug is a vasodilator. It has a positive effect on the microcirculation of angioprotectors and normalization of the rheological properties of blood.
Indications for use
Trental tablets and ampoules are used to combat the following diseases:
- Raynaud's disease.
- Pathologies of the respiratory system with obstruction.
- Gangrene.
- Pathological disorders of sexual function due to problems with blood circulation.
- Encephalopathy.
- Ischemic stroke.
Contraindications
Trental is not advisable for people with poor blood clotting, under the age of 18, with hemorrhagic stroke, as well as for women during pregnancy and breastfeeding.
Pharmacological properties
Vinpocetine has a combined effect on brain tissue, which includes a number of effects, for example:
Source: https://kcdc.ru/lekarstva/kavinton-tabletki-instrukciya.html
Contraindications
Among the common ones, it is worth noting intolerance to the component(s) of the drug:
- Kaviton 4 mg and Kaviton Forte 10 mg contain 140 and 180 mg of lactose, respectively (for lactose intolerance);
- 1 ampoule of Kaviton solution for infusion contains 160 mg of sorbitol (contraindicated or used with caution for diabetics).
Instructions for use for Cavinton ampoules indicate that the concentrate solution is contraindicated:
- severe form of hemorrhagic stroke;
- advanced arrhythmia;
- severe cardiac ischemia.
Use Cavinton (all forms) with caution in case of vascular hypotonicity and unstable blood pressure.
During pregnancy and lactation
The active components of the drug penetrate the placenta, but the concentration in the placental blood is lower than in the blood of a pregnant woman. With a high concentration of Cavinton in the womb, sudden abortions and bleeding in the placenta are possible (probably due to increased blood supply to the placenta).
Within an hour after taking the medicine, about 0.25% of the total dose is excreted in breast milk. It is prohibited to combine lactation and taking Cavinton .
For liver or kidney problems
Since the drug does not have nephro- or hepatotoxic properties, there is no need for dose adjustment.
Admission in childhood
The drug is not prescribed to children under 18 years of age due to insufficient research in this area.
What is the difference between the drug Cavinton Comfort and Cavinton: analogues, difference, instructions for use
Cavinton and Cavinton Comforte are medications containing vinpocetine as an active ingredient. This component, acting on the tone of the walls of blood vessels, has a vasodilating effect, acting primarily selectively on ischemic areas of brain tissue.
Under the influence of vinpocetine, the rheological properties of blood and the deformability of red blood cells improve, which contributes to a better supply of oxygen to tissues fed by small capillaries. The tolerance of oxygen starvation by nerve cells under the influence of vinpocetine increases significantly.
Cavinton and its analogues
Analogues of the drug with the same active substance are described in the table:
A drug | Dosage forms | Concentration of active substance, mg |
Cavinton | Tablets for oral administration | 5 |
Solution for intravenous infusion | 5 mg/ml | |
Cavinton Comfort | Dispersible tablets | 10 |
Cavinton Forte | Tablets for oral administration | 10 |
Vinpocetine | 5 | |
Telektol | 5, 10 |
Characteristics of the active substance
The effect of the active substance – vinpocetine – is aimed at improving cerebral circulation.
Pharmacodynamics
The effectiveness of the component is due to its ability to inhibit the enzyme phosphodiesterase, which subsequently leads to relaxation of myofibrils in the vascular wall by reducing the calcium concentration in the cytoplasm of smooth muscle fibers. The result of the effect of vinpocetine is the dilation of cerebral vessels, in which the substance has a special tropism.
Under the influence of vinpocetine, blood flow primarily increases in ischemic areas of the brain. As a result, oxygen saturation of the nervous tissue improves. The drug stimulates the utilization of glucose and increases the concentration of serotonin and dopamine in nerve cells. The ability of platelets to aggregate decreases, and the rheological properties of blood improve.
The effect of taking vinpocetine on systemic blood pressure is insignificant.
In the acute period of ischemic brain damage, the effect of vinpocetine on nervous tissue accelerates the extinction of general cerebral and focal neurological symptoms, improves memory and the ability to concentrate, as a result of which intellectual activity is activated.
Pharmacokinetics
Absorption of vinpocetine when taken orally occurs quickly. To achieve maximum concentration in blood plasma, 1 hour is enough. The substance is absorbed in the proximal intestine without being metabolized when passing through the intestinal wall.
Due to the peculiarities of the metabolism of the substance, patients with impaired liver and kidney function do not require dose adjustment. This property of the drug is due to its lack of ability to accumulate in the body.
Indications
The use of medications based on vinpocetine (Cavinton, Cavinton forte, Cavinton Comforte) is indicated in the following cases:
- cerebrovascular insufficiency,
- retinopathy,
- hearing disorders,
- vegetative disorders.
Cerebral blood flow disorders and neurological pathology
Vinpocetine preparations are effective for the following conditions:
- cerebral circulatory failure in acute or chronic form, including the acute stage of stroke and the residual period of acute cerebrovascular accident,
- transient ischemic attacks,
- encephalopathies of varying severity, having a discirculatory origin.
The remedy is also effective in the complex treatment of disorders of the autonomic nervous system during menopausal syndrome.
Cavinton in ophthalmological practice
In the field of ophthalmology, Cavinton in various forms finds its use in vascular diseases of the retina and choroid of the organ of vision. Preparations based on vinpocetine are effective for pathological conditions of various natures that arise against the background of:
- vascular atherosclerosis,
- vascular spasm,
- thrombosis and thromboembolism.
Vinpocetine preparations and otorhinolaryngology
Cavinton is used in the complex treatment of age-related, vascular, toxic and drug-induced hearing impairment, Meniere's disease, as well as dizziness of labyrinthine origin.
Adverse reactions
When using drugs containing vinpocetine, there is a possibility of the following adverse reactions:
Organ system | Side effects |
Hematopoiesis and the lymphatic system | Decrease in the content of formed elements in the blood and agglutination of red blood cells |
Immunity | Hypersensitivity reactions |
Trophism and metabolism |
|
Nervous system, including the central nervous system |
|
Organ of vision |
|
Organs of hearing and balance |
|
The cardiovascular system |
|
Digestive tract |
|
Skin and subcutaneous tissues | Hyperhidrosis |
General reactions | Allergic reactions in the form of skin hyperemia, rashes and itching |
Cavinton Comfort - what is the difference?
The difference between Cavinton Comforte and its analogues lies in the dispersible structure of the tablet. This dosage form will be convenient for patients who have difficulty swallowing pills due to disorders of various origins, such as:
- dysphagia as a result of organic damage to the central nervous system (after severe cerebral strokes or traumatic brain injuries),
- individual characteristics,
- neurological diseases characterized by swallowing disorders (myasthenia gravis, myasthenic syndromes, etc.).
Cavinton Comforte dispersible tablet can be swallowed whole with plenty of water, or dissolved in the mouth until completely dissolved. The tablets have a pleasant orange flavor, which makes taking the medicine even more comfortable.
Instructions for use
The methods of using various drugs containing vinpocetine are similar. The difference between drugs lies in the dose of the active substance.
Cavinton Comfort
The drug is intended for oral use after meals. The daily dose for an adult patient is 30 mg, divided into three doses (one tablet three times a day). However, if necessary, the attending physician may individually prescribe a different regimen for taking the drug.
For patients with impaired renal and (or) liver function, no dose adjustment is required. A noticeable therapeutic effect should be expected a week after the start of treatment.
The Cavinton Comfort tablet can be dissolved in the mouth without swallowing until completely dissolved. This is how this drug differs from other tablets based on vinpocetine.
Solution for infusion Cavinton
The product is intended for intravenous administration using slow drip infusions no faster than 80 drops per minute. The medicine cannot be used for intramuscular and intravenous injections without dilution.
Before infusion, the concentrate should be diluted in physiological sodium chloride solution or any of the dextrose solutions:
The prepared infusion composition with vinpocetine should be used no later than 3 hours after preparation. The initial dose in a course of intravenous infusion is 20 mg in 500 ml of saline.
Thus, for a patient weighing 70 kg, on average, the optimal dose is 50 mg in 500 ml of saline infusion solution.
The average duration of the course of infusions ranges from 10 days to 2 weeks.
For patients with hepatic and (or) renal dysfunction, no dose adjustment is required.
The instructions for use indicate that after completing the course of intravenous infusions, treatment should not be interrupted - it should be continued in the form of taking one of the vinpocetine preparations in tablet form:
- Cavinton.
- Cavinton forte.
- Vinpocetine.
- Telektol.
- Cavinton Comfort.
The dosage is usually from 5 to 10 mg per dose with a frequency of two to three times a day. The course of taking tablets is long - from 1 to 2 months. On the recommendation of the attending physician, a second course of therapy can be carried out after 4-6 months.
Source: https://fr-dc.ru/oftalmolog/kavinton-komforte-instrukcziya-po-primeneniyu-i-otlichiya-ot-analogov
Prices in online pharmacies in Moscow
Name of the drug Series Price, rub. Go to the online pharmacy
Cavinton® forte | 201.32 | |
Cavinton forte, tablets 10 mg; blister 15 cardboard pack 2; EAN code: 5997001359754; No. P N014556/01, 2007-08-15 from Gedeon Richter (Hungary) | 222.50 | |
Cavinton forte, tablets 10 mg; blister 15 cardboard pack 2; EAN code: 5997001359754; No. P N014556/01, 2007-08-15 from Gedeon Richter (Hungary) | 235.00 | |
Cavinton® forte | 240.00 | |
Cavinton forte, tablets 10 mg; blister 15 cardboard pack 6; EAN code: 5997001359631; No. P N014556/01, 2007-08-15 from Gedeon Richter (Hungary) | T17628A (until 07/01/2016) | 252.30 |
Cavinton forte, tablets 10 mg; blister 15 cardboard pack 6; EAN code: 5997001359631; No. P N014556/01, 2007-08-15 from Gedeon Richter (Hungary) | 254.60 | |
Cavinton forte, tablets 10 mg; blister 15 cardboard pack 6; EAN code: 5997001359631; No. P N014556/01, 2007-08-15 from Gedeon Richter (Hungary) | T17626A (until 07/01/2016) | 716.71 |
What is the difference between Cavinton and Cavinton forte?
Cavinton (vinpocetine) is a drug that corrects circulatory disorders in the brain. This product is formed on the basis of vincamine alkaloids contained in the plant of the genus Periwinkle (a perennial herb of the Kutrov family). Cavinton first began to be produced in the period 1975-1978.
Hungarian pharmaceutical organizations. In many countries, the drug is approved only as a food additive. It has an antiaggregation, vasodilating effect, improves and normalizes cerebral circulation. In the Russian Federation, the product is included in the list of essential life-saving drugs.
Pharmacology of the drug
Increases blood supply to areas subject to ischemia, relaxes the smooth tissue of brain vessels. Affects metabolism.
Slows down the processes of phosphodiesterase and adenylate cyclase, increasing the levels of cyclicity of adenosine monophosphate and ATP (adenosine triphosphate).
As a result, the blood vessels of the brain dilate, oxygen transportation improves, and the body’s resistance to hypoxia increases; the process of glucose absorption is activated, the process of metabolism and seratonin in the brain increases. Platelet dismerism decreases.
Cavinton forte
Cavinton Forte is a vinpocetine drug intended to improve cerebral blood flow and metabolic activity in brain tissue. Available in tablet form. Unlike Cavinton, it has additional components: lactose monohydrate, magnesium sterate, corn starch, colloidal silicon dioxides.
Pharmacology and pharmacokinetics of the drug:
Increases the brain's resistance to oxygen starvation and enhances the movement of glucose. Cavinton Forte concentrates ATP, stimulates metabolic processes in neurotransmitter systems. Improves the passage of red blood cells in blood vessels, enhances the effect of adenosine. It has a vasodilatory effect on blood vessels, reducing their resistance.
Easily penetrates through histohematic transitions, including the placenta, and is absorbed into breast milk.
Indications for use:
- Dizziness.
- Meniere's syndrome.
- Ischemic attacks.
- Traumatic brain injuries.
- Vascular dementia.
Contraindications:
- Extreme forms of IHD.
- Arrhythmia.
- Hemorrhagic strokes.
- Poor lactose tolerance.
- Allergic reactions to vinpocetine, periwinkle products.
- Pregnancy.
Directions for use: after meals. 1 tablet 3 times a day (no more than 30 mg.). The course of treatment is from 1 to 3 months (no more than 90 days). Prescribed by a doctor.
Side effects and overdose of Kaviton forte
- From the cardiovascular system (cardiovascular system) - signs of ischemia, extrasystole, decreased blood pressure.
- From the central nervous system - weakness, dizziness, insomnia.
- Rarely - dry mouth, discomfort in the gastrointestinal tract, dyspepsia.
There is no specific data on drug overdose.
In case of possible poisoning with the drug, adsorption and gastric lavage are prescribed.
Differences between drugs
Thus, we can highlight the main differences between these drugs:
- Different release forms (Cavinton - tablets and injections, Cavinton Forte - tablets only)
- Cavinton forte can interact (be used) with a large number of drugs.
- Both drugs differ in possible dosage (Cavinton - 5 mg of vinpocetine, Forte contains a double dose - 10 mg.)
- Cavinton forte contains an increased dose of the active substance.
Source: https://vchemraznica.ru/chem-otlichaetsya-preparat-kavinton-ot-kavinton-forte/
Synonyms of pharmaceutical groups
Pharmgroup Synonyms for pharmaceutical group
0070 Correctors for cerebrovascular disorders | Alpha blocker |
Blocker of "slow" calcium channels | |
Blockers of "slow" calcium channels | |
Vasodilator | |
Nootropic drug | |
Antimigraine | |
Other drugs affecting the central nervous system | |
Drugs that improve cerebral circulation | |
A drug that improves cerebral circulation | |
Cerebrovasodilating agent | |
Cerebrovasodilating agents |
Analogues of Cavinton in tablets and ampoules, which is better?
Comparing medications is necessary in order to make the right choice between them.
Cavinton (vinpocetine) is a drug that corrects circulatory disorders in the brain. This product is formed on the basis of vincamine alkaloids contained in the plant of the genus Periwinkle (a perennial herb of the Kutrov family). Cavinton first began to be produced in the period 1975-1978. Hungarian pharmaceutical organizations.
Cavinton is a drug that has a nootropic, antihypoxic, and vasodilator effect. It improves blood circulation in the brain, normalizes brain metabolism, increases the amount of glucose and oxygen consumed, and reduces the resistance of blood vessels in the head. The active ingredient is vinpocetine.
Indications for the use of the drug include ischemic stroke, consequences of hemorrhagic stroke, vascular dementia, cerebral atherosclerosis and other diseases associated with circulatory failure in the vessels of the head.
For ophthalmological diagnoses, Cavinton is prescribed for diseases of the choroid of the retina. For otorhinolaryngological problems, the drug is prescribed for Meniere's disease, idiopathic tinnitus, for the treatment of perceptual hearing impairment.
The medicine is manufactured in Hungary, as well as in Russia. The price for Cavinton varies from 240 to 700 rubles. Release form: tablets, injection solution. There are many cheap analogues of the drug and close substitutes made in Russia or imported.
Which is better: Cavinton or Vinpocetine? What is the difference?
The first analogue of Cavinton presented is Vinpocetine. The instructions say that the medicine has vasodilating, antihypoxic and antiaggregation properties. Vinpocetine is available in the form of powder and concentrate for intravenous administration.
Cavinton or Vinpocetine is used to eliminate problems with cerebral circulation, which are the main cause of stroke. Vinpocetine and Cavinton are effective medications for the prevention of vascular accident.
Cavinton or Vinpocetine is used to eliminate problems with cerebral circulation, which are the main cause of stroke.
Vinpocetine has the same pharmaceutical properties as Cavinton. According to the main characteristics, these are the same drugs.
Vinpocetine has the same pharmaceutical properties as Cavinton.
These drugs can be interchanged, because there are no differences between them. The only requirement for patients is to prohibit the simultaneous use of Cavinton and Vinpocetine to avoid overdose.
When taking Cavinton Forte, take this fact into account and reduce the number of tablets accordingly.
Because These medications contain the same substance, they have the same degree of effect on the body. Some experts recommend Cavinton - it contains purified and high-quality components. The effectiveness of each drug is the same. According to some patients, Cavinton is better tolerated.
Anna, 42 years old, Stavropol: “Over the last few months I began to feel pain in the head and difficulty concentrating. The doctor said that these were signs of beginning cerebral circulatory disorders and advised preventive use of Cavinton, 1 tablet 3 times a day. At first I did not notice the effect of this product.
Irina, 63 years old, St. Petersburg: “Cavinton helps to constantly keep yourself in good shape. The medicine effectively fights fatigue, headaches, and irritability.
“I take medications to prevent the formation of blood clots, and I have limited the amount of salt in my diet.”
The drug Cavinton Forte will improve cerebral circulation
Cavinton forte or Cavinton are drugs used to eliminate cerebrovascular accidents.
Medicines have an antiaggregation effect on the body, promote vasodilation, improve and normalize blood flow in the brain.
The drug is available in the form of tablets and concentrate for the preparation of infusion solution.
Cavinton contains the active component vinpocetine. In addition to the active substance, the tablets contain additional components that play a supporting role:
- talc;
- silicon dioxide;
- magnesium stearate;
- lactose monohydrate;
- corn starch.
In the composition of the concentrate for the preparation of infusion solution, the auxiliary compounds are:
- tartaric acid;
- sodium disulfite;
- water for injection;
- benzyl alcohol;
- ascorbic acid;
- sorbitol.
The tablet form is packaged in blisters; the tablets are white in color. The concentrate for the preparation of infusion solution is a clear liquid.
The main active ingredient belongs to the group of cerebrovasodilating agents. The use of the drug improves metabolism in tissue cells and blood supply to the brain. Cavinton is able to influence the rheological properties of blood. Under the influence of vinpocetine, the activity of transmembrane calcium and sodium channels, AMPA and NMDA receptors is inhibited.
Cavinton is able to influence the rheological properties of blood.
Under the influence of vinpocetine, the absorption and metabolism of oxygen and glucose by brain tissue cells improves, and the processes of serotonin and norepinephrine synthesis are activated. The drug is able to have antioxidant and stimulating effects on the noradrenergic system of the body.
Indications for use of the drug are extensive:
- in neurology - ischemia, vascular dementia, stroke, cerebral vascular atherosclerosis, vertebrobasilar insufficiency, post-stroke condition, hypertensive, post-traumatic encephalopathy and other types of cerebral circulatory failure, memory impairment, headaches and motor activity disorders;
- in ophthalmology - spasm of retinal blood vessels, atherosclerosis, degenerative diseases, development of secondary glaucoma, thrombosis, embolism;
- in otorhinolaryngology - age-related hearing loss, hearing impairment of toxic and vascular origin, cochleovestibular neuritis, Meniere's disease, dizziness, the appearance of tinnitus, vasovegetative manifestations in the menopause.
Source: https://nevrolog-info.ru/kavinton-analogi/
Cavinton forte and comfort - analogues of tablets
Preparations based on vinpocetine have a vasodilating effect, thereby increasing their permeability, as well as improving oxygen exchange and blood flow in the brain.
Such medications include Cavinton, which is available in ampoules with an injection solution and in the form of tablets.
In the register of medicines (RML) it is classified as a medicine for improving blood circulation in the brain.
For Cavinton, vinpocetine is not only the main active ingredient, but also the INN (international nonproprietary name). Among other analogues with this component, this drug is famous for its greater degree of purification during production, which is why its price is higher than the cost of many other similar medications.
There are also versions of Cavinton, namely:
- Cavinton Forte;
- -Comfort;
- In the form of an injection solution.
The differences lie only in the amount of the main active ingredient and the method of administration. However, unlike Cavinton Forte in tablets, the Comforte version is able to dissolve in the mouth, which is a useful feature if the patient has problems swallowing.
Features of the drug
Both Comfort and Forte serve to dilate blood vessels located in the brain. The effect allows you to improve blood flow and the supply of oxygen with glucose.
The result is achieved thanks to vinpocetine, which is able to relax the smooth muscle tissue of blood vessels.
In addition to the main effect, the medicine stimulates the exchange of norepinephrine and serotonin in the brain, reduces blood viscosity and makes red blood cells more elastic.
Cavinton 5 mg is the regular version of the drug, there are usually 50 tablets in a package, and 5 mg means the amount of the main active ingredient. Prescribed for prophylactic purposes and for mild forms of the disease.
Forte is a more advanced form of the drug and contains 10 mg of vinpocetine. This type is created in the form of tablets of 30 and 90 pieces. For the drug Cavinton Forte, the prefix means modification. She talks about increasing the amount of the main component.
However, it is impossible to say for sure that Forte is better than the regular version due to a more serious concentration of vinpocetine. In some cases, the usual dose of the main active ingredient was more effective, but the modified model caused side effects.
Other experts noted situations in which the result after treatment with Cavinton Forte tablets turned out to be more significant than that of its simple version.
There is also a version of Cavinton in the form of an injection solution. This form is characterized by ampoules of 2.5 and 10 ml, in a package there are 5 and 10 pieces. 1 ml of this solution contains 5 mg of the main active ingredient, so you need to select the dose carefully and without the knowledge of the doctor, it is better not to take this drug at all.
Use of the drug
According to the instructions included in the package, you should take the medicine after meals to reduce the likelihood of side effects. After achieving the desired effect, the doctor will reduce the dosage to a minimum to maintain the effect.
The course of treatment lasts 2-3 months, but the patient’s condition improves mainly after 10-14 days. If you need to discontinue the drug, this should be done gradually.
With other forms of Cavinton (Forte and Comfort), there is no significant difference in administration and the dosage, as in the case of the simple version, should be selected by the attending physician.
The drug in the form of a solution is used to treat neurological pathologies and circulatory disorders. Before use, the medicine must be mixed with saline and then administered by drip. When the desired result is achieved, the patient is transferred to tablets.
Cavinton is also used to treat childhood pathologies, especially seizures after a head injury. In this case, an injection solution is used, and when visible results are achieved, the child is given the drug in tablet form to maintain the effect. The course of therapy is carried out under the supervision of a doctor; it is not recommended to use the medication on children under 18 years of age.
Side effects
If used incorrectly or if the interaction of drugs with each other has not been taken into account, the following side effects occur:
- Nervous system: Weakness;
- Dizziness;
- Sleep disorders;
- Headache.
- Sudden pressure surges (increases and decreases greater than permissible values);
- Nausea, vomiting;
- Heavy sweating;
Cavinton increases blood pressure only if an adverse reaction occurs. Normally, after using the drug, it decreases slightly.
Drug interactions
According to tests, Cavinton has negative compatibility with the following substances:
- A-methyldopa. When they are combined, the hypotensive effect is enhanced;
- Heparin and amino acids. Using them in the same mixture for drip injection is strictly prohibited, since chemically they are not compatible.
Cavinton price
The average price for Cavinton in Moscow pharmacies is as follows:
- Solution 2 ml. 10 ampoules - 230-250 rubles;
- 5 mg 50 tablets – 240-250 rub.;
- Forte 10 mg. 30 tab. – 260-280 rub.;
- Comforte 10 mg. 30 tab. – 320-340 rub.
Cavinton is a reliable means of stimulating cerebral circulation. Despite the price, the drug is used more often than other drugs containing vinpocetine due to its less toxic composition and time-tested and statistically proven effect.
Source: https://NashiNervy.ru/o-nervnoj-sisteme/preparat-kavinton-i-ego-analogi.html
Side effects
Taking Cavinton is quite rarely accompanied by side effects, but after carefully reading the instructions for use for Cavinton injections and tablets, the following were discovered:
- Cardiovascular system: instability of blood pressure, increased symptoms of existing arrhythmia (infrequently), tachycardia, ECG changes (prolongation of the QT interval, ST segment depression), untimely heart contractions; inflammation of the venous walls (solution); hot flashes (tablets only).
- Nervous system: drowsiness or insomnia, headache, dizziness, weakness (usually a symptom of an underlying disease).
- Digestive system: nausea, dry mouth, heartburn.
- Skin reactions: urticaria, rash, redness of the skin (during infusion), increased sweating.
Some patients noted a feeling of hunger after consuming Cavinton.