Glycine is a metabolic agent, a metabolic regulator designed to improve the functioning of the central nervous system, reduce emotional stress, increase brain activity and overall performance. This is an essential amino acid for the body with a sweet taste, which is prescribed as a nootropic drug.
Glycine is not only found in living cells. In 2006, an American spacecraft delivered to Earth a capsule with unique samples of stardust - the oldest particles, the age of which was equivalent to 4.5 billion years. Traces of glycine were found in the samples studied. And in 2020, glycine was discovered in a gas cloud accompanying one of the comets.
Glycine: amino acid
Glycine is the simplest aliphatic (i.e., not forming aromatic bonds) amino acid involved in the biosynthesis of proteins.
Glycine is also called aminoacetic acid, under this name it is listed in the composition of the medical drug “Glycine”. This amino acid is part of the substance used in developing photographs. Glycine is an essential amino acid for the human body, along with amino acids such as lysine, tryptophan, and glutamine.
Glycine: formula
The chemical formula of glycine is NH2 – CH2 – COOH; the amino acid can be obtained by protein hydrolysis or chemical synthesis. (Hydrolysis is carried out with proteins that have already been isolated in another way, this process is carried out in order to increase their nutritional value).
Description
Glycine is available in tablet form. Recommended method of use is dissolution under the tongue. Glycine has a sweetish taste (hence its name - “glycis” means “sweet” in Greek), and therefore children take it with pleasure. There is no need to take the tablet with water. The effectiveness of glycine does not depend on food intake. The shelf life when stored at a temperature not exceeding 25 ºС is 3 years.
Compound
The composition of the drug, in addition to the amino acid itself, includes excipients: 1 mg of methylcellulose, 1 mg of magnesium stearate. The mass of the active substance is 100 mg.
Glycine preparations are also produced, which contain B vitamins - B1, B6 and B12, as well as tablets with a different dosage.
Glycine Extra is a food additive that regulates metabolic processes. Thanks to this drug, inhibition processes in the central nervous system return to normal and are activated. Thanks to Glycine Extra, you can eliminate psycho-emotional stress and increase intellectual performance.
Can improve mood, eliminate conflict and aggressiveness, and increase mental performance. Taking the drug will help reduce the manifestations of cerebral disorders.
The drug is not an antibiotic, but it can be combined with the use of this group of drugs. It does not matter how Glycine Extra is taken: before meals or after meals. You need to drink the product for 30 days. Afterwards, take a break and you can take a second course.
It is highly recommended to take it on critical days, as a woman needs vitamins. Indicated for HIV, but dosage may need to be increased.
Can be combined with drinking alcoholic beverages. Taken to cure alcohol addiction. It is not recommended to drive a vehicle while taking the course. Lowers blood pressure slightly.
Some diagnoses
This amino acid is quite poorly absorbed in the body. But science does not stand still. Thanks to special technology, this problem was solved. Glycine sublingual tablets have high bioavailability. They should be sucked behind the cheek or under the tongue. The active substance quickly penetrates through the oral mucosa into the blood, with a current that spreads throughout the body.
For children who cannot yet consciously dissolve tablets in the cheek, it is best to crush the drug into powder and dip the pacifier in it. The baby will suck it with pleasure.
By following these simple rules for taking Glycine, its dosage and course, you can significantly alleviate your condition and help your child or loved ones. The drug has virtually no contraindications (except for individual intolerance) and does not cause side effects.
For children, “Glycine” is easy to use precisely because of its taste. For maximum effect, the tablets need to be dissolved, and children can easily cope with this, since the medication does not cause discomfort. You can take the drug to stimulate metabolic processes in brain tissue. True, it is categorically not recommended to prescribe it for yourself.
Knowing how to take “Glycine” in tablets for an adult (the instructions tell you about this in detail), you can overcome the following troubles:
- depressive disorders;
- anxiety;
- depressed mood;
- irritability;
- lack of attention;
- sleep problems.
The drug is sold in tablets, each containing 100 mg of the active substance. The product is intended for long-term resorption; it should not be washed down with water. It is best to put the tablet under the tongue and wait for it to dissolve on its own under the influence of human saliva.
The method is called sublingual. This is what the doctor will talk about at the appointment, explaining how to take “Glycine” in tablets for an adult (photos on the Internet confirm that this is exactly how people use the medicine).
An alternative option for using the drug is to dissolve a tablet placed between the gum and cheek. Occasionally, preliminary grinding of the medication to a powder state is allowed.
It is known how to take “Glycine Bio” in tablets for an adult when a stroke is detected in which brain tissue is damaged. Normally, the daily dose reaches a gram; it is recommended to use the product in powder form, stirring it in a teaspoon of purified (preferably distilled) water. When the condition shows persistent improvement, the dosage is reduced: a couple of tablets are used three times daily with food. The duration of this program is one month.
How to take “Glycine Forte” tablets for an adult for insomnia: the product must be used half an hour before going to bed. The tablet is dissolved by holding it under the tongue and waiting until the medication is completely dissolved. For children, the dosage is halved, leaving the scheme of use the same.
Many people are interested in how to take “Glycine” tablets for an adult: before meals or after? The instructions for the drug contain clear instructions on the optimal norms: the product is intended for use half an hour after a meal. This is due to the characteristics of the active substance: aminoacetic acid can cause stomach problems if the medication is used on an empty stomach.
Patients suffering from gastritis and peptic ulcers should be the most careful. In childhood, glycine is intended for therapy strictly in the volume and duration of the course as recommended by the attending physician. It is believed that the medication is not addictive, however, it is important to adhere to the established rules.
When it enters the human body, “Glycine” normalizes metabolism, affecting the production of hormones. This is especially noticeable in the concentration of adrenaline in the blood, since aminoacetic acid blocks its generation by tissues. At the same time, toxins and free radicals that can negatively affect the brain are eliminated.
Regular use of the drug in accordance with the instructions for use allows you to achieve quality sleep and improve your standard of living, efficiency and performance in everyday life, as well as adapt to a new social environment.
What factors determine how much Glycine you can take per day?
- Age. The drug can be given even to infants and taken in old age, so the dosage changes taking this factor into account.
- What is the drug used for? How much Glycine you need per day depends on the reasons for use. For example, to improve sleep, half or one tablet is enough, but for a stroke, 10 tablets with a small amount of water are used at once.
- Individual appointment. Consultation with your doctor will help you adjust your dosage regimen and the number of tablets for daily use to achieve maximum effect.
For sleep disturbances (frequent awakenings, difficulty falling asleep, etc.), prescribe ½–1 tablet 20 minutes before going to bed, or immediately before bedtime.
To improve concentration and memory, in case of mental stress, stress leading to psycho-emotional tension, a course is prescribed for 2-4 weeks with a dosage of the drug 2-3 times a day, 1 tablet. Similarly, the drug is given to children and adolescents to correct social deviation and mental retardation.
If there is a risk of ischemic stroke, adults can simultaneously take 10 Glycine tablets sublingually, and if a stroke is suspected, crushed and slightly diluted with water.
In the presence of lesions of the central nervous system of various types, which are accompanied by mood swings, excessive excitability, insomnia, etc., the course is 1–2 weeks. Tablets are taken 1 pc. 2–3 times daily. A repeat course is carried out after a month, if necessary.
In narcology, the drug is used as a means to help reduce stress and improve mental performance. For encephalopathy and PNS, a course is prescribed for 2–4 weeks with 1 tablet. 2–3 times a day. The drug is repeated 4–6 times a year.
The information provided on how many Glycine tablets can be taken per day is intended for children over 3 years of age, adolescents, and adults. For infants and children under 3 years of age, the dosage is reduced. For damage to the central nervous system, excessive excitability, and sleep disorders, it is prescribed to give ¼–½ tablet. 2–3 times a day. The duration of the course is 1–2 weeks, then the tablets are given in ½ pcs. daily for 7–10 days.
Glycine: how it works
Glycine is an amino acid that can be produced by the body itself. The drug is prescribed as a mild sedative and to improve brain function.
Glycine acts on nerve cells, regulating active processes (excitation, inhibition) - it reduces hyperactivity and calms, a similar effect is exerted by taurine (a sulfonic acid formed from an amino acid). The substance easily and quickly penetrates the nervous system, improves brain nutrition, helps improve memory, and increases mental performance.
Composition (active ingredient)
According to the manufacturers of the drug, the amino acid (the main component of the white tablets) protects the nervous system from harmful environmental influences. There is no official confirmation of such features of the drug; the information is compiled on the basis of instructions for use and reviews of people taking Glycine.
Aminoacetic, or aminoethanoic, acid is a natural substance for the body, present in proteins responsible for regulating the nervous system. It has nootropic properties that can improve brain function, reduce fatigue and increase stress resistance. The medicine “Glycine” offers to fill the shortage of a natural drug. It is available in various dosages - from 100 to 500 mg of amino acid. The package usually contains 50 tablets.
Side effects
Glycine is always present in your body, even if you have never taken glycine, do not know what it is for, or even know what it is. Another name for the substance is aminoacetic acid. It belongs to the class of amino acids and is produced by the human body, being one of the 20 essential amino acids necessary for normal development and functioning. This amino acid has many important functions in the body, primarily in the nervous system.
The parasympathetic nervous system, which operates at rest, is responsible for many body functions. However, the activity of the sympathetic nervous system, which is activated under stress, is also important. Modern people are increasingly susceptible to stress - this is due to the rhythm of life - many of us are in a hurry, running, worrying about a variety of reasons. Such a life leads to stress, decreased concentration and mental performance, poor memory, and poor sleep.
Glycine is designed to solve these problems. It has the properties of a neurotransmitter and is part of the proteins responsible for inhibition processes in the nervous system. This amino acid also has alpha-adrenergic blocking, antioxidant and antitoxic effects. Glycine is also found in many foods, such as nuts and eggs.
What glycine can protect against:
- Psycho-emotional stress
- Aggressiveness
- Conflict
- Insufficient social adaptation
- Bad mood
- Bad dream
- Low mental performance
- Vegetovascular disorders
- Hypertension
- Sweet cravings
In addition, the medicine can be used as one of the means in complex therapy of diseases such as:
- Stroke
- Traumatic brain injuries
- Poisoning with alcohol and other substances that depress the central nervous system
It should be borne in mind that there is no scientific evidence of a serious effect of glycine when used as a means of improving mental performance in healthy people. And this is understandable, because since glycine is synthesized in the body, healthy nerve cells do not really need the extra amino acid.
Another thing is damage to the tissues of the nervous system when there is not enough substance in the body. The benefits of amino acids for various brain injuries are undeniable. In particular, glycine is important for children, especially infants, who have postpartum injuries that negatively affect the functioning of the nervous system. There are also studies showing improved sleep as a result of taking glycine preparations.
Glycine has almost no contraindications. It can be prescribed to infants, adults and the elderly. The drug is approved during pregnancy and lactation. The most serious contraindication is individual intolerance to the substances contained in the tablet.
Glycine also has few side effects. Rare side effects - lethargy, weakness, drowsiness, low blood pressure. Therefore, the drug should be taken with caution by people with arterial hypotension. No effect of the drug on concentration of attention and speed of psychomotor reactions was found.
Since glycine is a natural substance for the body, it does not accumulate in tissues, but is quickly broken down and excreted from the body. Among the interactions with other drugs, a weakening of the effect of neuroleptics, antidepressants, hypnotics and anticonvulsants should be noted. The drug is available in pharmacies without a prescription.
Glycine is a long-acting drug, i.e. it should be taken in long courses. Glycine is well accepted by the body because there are receptors in the brain and spinal cord responsible for recognizing this amino acid. Once in the gastrointestinal tract, glycine is quickly absorbed into the blood and distributed throughout the body. It decomposes in the liver into water and carbon dioxide and is excreted from the body.
How the drug works:
- activates metabolic processes in the brain;
- takes part in the transmission of nerve impulses;
- blocks the production of stress hormones: adrenaline, norepinephrine;
- gets rid of toxins that destroy brain cells;
- relieves the effects of stress on the nervous system;
- helps speed up recovery after strokes;
- reduces the effects of alcoholism and drug addiction on the central nervous system.
Glycine has virtually no side effects. Manufacturers of the drug note the possibility of allergic reactions to the main or auxiliary components. In addition, glycine can enhance the effect of other drugs of similar properties.
With prolonged use, a laxative effect may occur. Some patients experience allergic reactions.
It is important
You can use “Glycine” and antidepressants, medications from the category of sedatives and sleep normalizers at the same time. It is known that Glycine reduces the side effects caused by the mentioned categories of drugs.
You cannot continue Glycine therapy if headaches begin, you feel dizzy, or feel nauseous. Manifestations of an allergic reaction on the skin and loss of appetite are possible. All these symptoms indicate intolerance to the drug and require discontinuation of its use. When visiting your doctor, you should report any symptoms caused by the medication.
Glycine: instructions
A doctor may prescribe glycine in the following cases:
- Deviant behavior of a child
- Low mental performance
- Prolonged stress
- Neuroses and neurosis-like conditions
- Vegetovascular dystonia
- Traumatic brain injuries
- Perinatal damage to the nervous system
- Encephalopathies
- Ischemic stroke
When prescribing glycine tablets, the doctor gives instructions for use suitable for each specific case. The recommended dose depends on the disease.
When treating brain lesions with glycine preparations, the dosage is the same. The duration of the course is 2 weeks, but can be extended to 1 month.
For sleep disorders, it is recommended to take the tablet half an hour before bedtime.
For ischemic stroke - 10 tablets under the tongue within 3-6 hours after the stroke, then 10 tablets per day for 5 days, then 3 tablets per day for a month.
For drug and alcohol addiction, toxic encephalopathy - 2-3 tablets per day for a month.
In case of decreased performance or deviant behavior in children, you should usually take 2-3 tablets of 100 mg 2-3 times a day. The duration of the course is 2-4 weeks.
Glycine should be given to children under 3 years of age at half the dose (50 mg instead of 100).
If glycine is needed by an infant who cannot take a pill, then the drug is prescribed to the mother, and the amino acid enters the child’s body through breast milk.
Glycine is indicated for various disorders of the nervous system (stress, depression, anxiety, increased excitability) and disorders of brain activity. Glycine is prescribed to children and adults.
The Russian drug “Glycine” is available in tablet form. One tablet contains 100 mg of active substance. There is no need to drink the medicine with water, but put it under the tongue and dissolve or buccally, keep it in the oral cavity for as long as possible.
It is necessary to follow the recommended dosage of glycine, which is determined individually for different diagnoses. Adults are prescribed 100 mg 2-3 times a day for two weeks or a month, adolescents can be prescribed up to 300 mg per day, children 50 mg or even less, depending on age and strictly on the doctor’s recommendation. After an ischemic stroke, the dosage should be 1000 mg per day. To improve sleep, one tablet before bed is enough.
Although glycine is considered a harmless drug, excessive use can lead to an overdose.
Signs of overdose:
- A sharp decrease in blood pressure, darkening of the eyes, dizziness, weakness.
- Increased sleepiness.
- Apathy.
- Inability to concentrate on a specific action.
- Impaired liver and kidney functions.
Is glycine okay for children? Glycine is an amino acid that is present in the human body and its deficiency can adversely affect it. The period of active growth in children is accompanied by various disorders of the nervous system; many experience increased excitability and hyperactivity. In such cases, doctors recommend giving children glycine as a sedative.
Glycine is recommended for children under one year of age and older for hyperactivity and sleep disorders; it calms and normalizes nervous processes in the child’s body and helps accelerate the child’s development.
Due to age characteristics and the inability to perform certain actions, a child cannot take glycine according to the rules, so it is recommended to add it to food: formula, milk, complementary foods.
Instructions for use of “Glycine” are detailed and informative. It describes both the properties and effect of the drug, as well as the dosage for taking the medicine. If the attending physician has not prescribed a specific dosage. You can safely refer to the instructions and follow its recommendations.
Glycine has no contraindications, except for individual intolerance to the substances included in the drug. This happens because glycine is a natural amino acid in the human body.
Prescribed for the following pathological conditions:
- decreased intellectual activity;
- ischemic stroke;
- excessive emotional and psychological stress;
- various functional and holistic ailments of the nervous system;
- deviant forms of behavior in children.
Contraindications are:
- personal intolerance to a component in Glycine Extra;
- carrying a baby;
- lactation.
Glycine Extra is taken buccally or sublingually in the form of tablets or a powder mixture after crushing the tablet. Healthy children and adults should take one tablet three times a day for emotional and psychological stress, delayed rates of intellectual development, decreased intellectual performance and memory. The duration of the course is from two weeks to a month.
For functional and holistic pathologies of the central nervous system, which are accompanied by overexcitability, sleep disturbances, and emotional incontinence, children under three years of age are prescribed half a tablet 3 times a day. The duration of the course is from a week to two. Then take half the dose once a day for 7 days.
Children older than this age and adults are advised to take one tablet 3 times a day. Use up to two weeks. Cure can be extended to 30 days. If necessary, take a second course in a month.
In case of problems with dreams, drink one tablet half an hour before bedtime.
In the case of ischemic stroke, during the first 6 hours from the onset of the disease, take 1 g with a small spoon of water. After up to 5 days, take 1 g per day. After 30 days, 2 tablets three times a day.
Do not take during pregnancy and lactation.
Special case
It is best to read the manufacturer’s instructions on how to take Glycine Bio tablets for an adult. This also applies to some other types of the drug. The fact is that not only pure aminoacetic acid is available for sale, but also improved by the inclusion of vitamin and mineral complexes.
For such products, the manufacturer develops a unique use program, which is described in the accompanying documentation. You will have to follow both the rules regarding the use of the pill and the recommendations on the frequency of dosing and the duration of the radiation program.
The instructions on how to take “Glycine Forte” in tablets for adults are of quite great interest to the general public. This drug is popular because half of the weight of each tablet is vitamins that are beneficial to humans. The manufacturer recommends using one capsule three times a day. This program is suitable if you are worried about irritability.
An increase in dosage may be recommended by the attending physician if no positive effect is observed with the current course. Much depends on the specific case, the diagnosed pathology, and the general condition of the sick person’s body.
Glycine: properties
Since aminoacetic acid is present in the human body and is easily absorbed, the drug glycine has a lot of useful properties, and it acts gently and is not addictive:
- soothing;
- anti-anxiety (tranquilizing);
- antidepressant, improves mood;
- anti-anxiety (for alcoholism and drug addiction);
- metabolic (accelerate and qualitatively improve metabolic processes in the spinal cord and brain), accelerates recovery processes after strokes and traumatic brain injuries;
- improving brain performance and enhancing mental activity.
Analogues and substitutes
Glycine also has analogues, but it is still the same drug with different names - Glycine Forte Evalar (300 and 600 mg tablets), Glycine-Canon (1000 mg tablets), Glycine-Bio, Glycine Active, Glycine-Vis (capsules 300 mg). Glycine Forte Evalar and Glycine-Vis also contain B vitamins, which are designed to enhance the beneficial effect of the amino acid on nervous activity. In addition, these products, like Glycine Active, are not medicines, but dietary supplements.
Indirect analogs of glycine can also include other nootropic drugs, such as tryptophan, phenotropil, piracetam, glutamic acid, mexidol, etc. However, their mechanism of action is somewhat different and in most cases they will not be able to replace glycine.
Analogues of Glycine Extra are:
- Menovalen;
- Relaxil;
- Sanval;
- Homeostress;
- Sanason Lek;
- Sonmil;
- Piklon;
- Vernison.
Recently, glycine analogues have appeared on the market of medicines and dietary supplements. Preparations are produced containing glycine with the addition of vitamin B6, vitamin B12 and minerals.
Such drugs act as sedatives for stress, depression, the substances included in the composition treat sleep disorders.
Under stress
1. CALM CP (60 capsules) from the manufacturer NeuroScience - a natural drug that helps overcome anxiety and nervousness.
Includes:
- banana extract,
- enriched soy lecithin,
- glycine,
- taurine,
- and excipients - microcrystalline cellulose, magnesium stearate, silicon dioxide.
Banaba extract and lecithin regulate the production of cortisol (the “death” hormone that breaks down proteins), while glycine and taurine soothe. It is recommended to take 1 capsule before bedtime, after consulting with your doctor. People who take this drug say that it is more effective to take it in the morning because it can be difficult to fall asleep after taking it in the evening.
2. GABA CALM (120 sublingual tablets) from Source Naturals - an effective drug for stress and increased nervousness.
Includes:
- GABA (gamma-aminobutyric acid, involved in brain metabolism),
- glycine,
- taurine,
- N-acetyl L-tyrosine (an amino acid involved in protein synthesis, blocking the formation of adrenaline and norepinephrine).
The drug acts on nerve cells, inhibits the sending of electrical impulses, which helps reduce nervous tension. You can use it at any convenient time, sublingually or buccally, but not more than 3 capsules per day.
For depression
3. TravaCor (120 capsules) from NeuroScience - a drug that effectively fights depression and improves mood.
Includes:
- amino acids (theanine, taurine);
- vitamin C, as well as B6 and B12;
- minerals: magnesium, zinc, selenium.
Active substances fight anxiety, increase performance, improve mood, and prevent the formation of adrenaline, which has a destructive effect. You can take 1-3 capsules three times a day, it is recommended to start with a small portion.
4. Extress, (60 capsules), from Vaxa International - a homeopathic remedy that has a gentle effect on the nervous system. The components of the drug actively fight anxiety, disorders and depression, and improve mood.
For sleep disorders5. Melatonin Complex, (100 tablets) from Source Naturals is an effective sleep aid, which includes:
- melatonin (a hormone that regulates daily routines),
- glycine,
- taurine,
- vitamin B6.
Take one tablet before bed; some people recommend half the dose.
6. Happy Sleeper (60 capsules) from Natural Balance - an effective sleeping pill that helps regulate the internal clock and establish sound sleep without waking up at night. The composition of the drug includes:
- melatonin,
- glycine,
- GABA,
- valerian root extract,
- lemon balm and English lavender extract.
Take two capsules before bed, after consulting with a specialist.
Customer Reviews
Arina Konstantinova, Moscow
“I took this supplement as prescribed by my doctor for three weeks. I can't say I really liked it, but some improvements are noticeable. I really coped with the overstrain and it seems to me that my brain has rested. The depression I couldn’t cope with has gone away.”
Oleg, Moscow
“Grandfather had a stroke, they thought he would not survive. But God was merciful and everything worked out. The doctor prescribed Glycine Extra as an adjuvant therapy. After taking it, there was an improvement in my grandfather’s health. Brain function has improved. Thanks a lot. I recommend."
