Noopept is an innovative Russian-made drug from the group of nootropics. It is used to improve cognitive abilities in elderly people, patients with various cerebrovascular disorders and people with increased mental and physical activity.
About the drug, composition and release form
The development of the substance began in the USSR, and only recently the drug entered the pharmaceutical market. Its creation took place at the Research Institute of Pharmacology named after. V.V. Zakusova RAMS. According to doctors, Noopept has gained wide popularity compared to other drugs with nootropic activity. The drug has undergone many clinical studies and its positive effect on brain function has been fully proven.
Noopept is produced in the form of round, flat white tablets, which are packaged in a cell blister (25 pieces) or in a polymer jar (30-50 pieces). Secondary packaging – cardboard box. The active ingredient of the drug is the original developed substance Noopept, its chemical name is N-phenylacetyl-L-propylglycine ethyl ester. In addition, the tablets contain microcrystalline cellulose, lactose monohydrate, povidone monohydrate, potato starch and magnesium stearate. One tablet contains 10 mg of the main component.
Noopept, photo
Entering the body, Nootpent is not yet a pharmacologically active substance. Only during certain biochemical processes does the active metabolite of the drug, cycloprolylglycine, form. This compound is normally produced in the body and is considered a “memory peptide.”
Thus, Noopept has a natural effect on the body, which is why the drug has a small number of side effects and contraindications. The mnemotropic effect of the drug is due to its effect on the synaptic structures of the hippocampus. This drug has a multiple range of pharmacological actions that are aimed at improving brain function:
- Antiamnestic effect;
- Antioxidant action. Reduces the negative impact of free radicals.
- Neuroprotective effect. Increases the stability of brain cells under hypoxic conditions, after injuries, and also reduces the negative impact of toxic substances;
- Cholinergic activity. Acting as an analogue of natural acetylcholine in the central nervous system, the drug improves the transmission of nerve impulses in different parts of the brain;
- Normalizes the rheological properties of blood due to antiplatelet, anticoagulant and fibrinolytic effects. Against this background, the risks of cerebrovascular pathologies are reduced, microcirculation is improved and blood supply to the brain is optimized.
The use of Noopept tablets optimizes memory performance at all stages. The assimilation, storage and reproduction of information improves, unlike other nootropics, which affect only the initial stages of information processing. The drug has a slight anxiolytic effect.
In addition, a positive effect on the autonomic system was noted. Taking the drug relieves symptoms such as dizziness, headaches, tachycardia, etc. Stopping the use of the drug is not accompanied by a withdrawal reaction.
Composition and release form
The drug is available in the form of round tablets of 10 mg, white, flat-cylindrical with a chamfer . Contents of each package: 2 blisters of 25 tablets each and instructions for use of Noopept. The composition is as follows:
| Active substance | Noopept (n-phenylacetyl-l-propylglycine ethyl ester) | 10 mg |
| Excipients | Potato starch | 13.5 mg |
| Lactose monohydrate | 55 mg | |
| Microcrystalline cellulose | 21.2 mg | |
| Magnesium stearate | 0.3 mg | |
| Povidone | 0.0008 mg |
Reviews from neurologists
The drug has many good reviews from neurologists. Experts say that the product has a complex effect, is characterized by high safety indicators and extremely rare occurrence of side effects.
According to experts, Noopept improves cognitive functions, removes absent-mindedness, brain fog and memory gaps. Neurologists talk about a wide range of uses of the drug. It is prescribed to patients with many neurological disorders, in unfavorable conditions, as a stimulant of memory and attention.
Noopept, according to the instructions for use, is systematically prescribed by doctors as the most effective nootropic substance, which generally enhances cognitive brain functions. Real reviews from people and doctors say: the nootropic has proven itself to be an effective tool in the regeneration of human memory. Noopept is well tolerated and works even with complex therapy.
pharmachologic effect
Noopept is a drug that has nootropic, neuroprotective properties . It has a positive effect on the learning process and memorizing information. The neuroprotective effect is expressed in the development of increased resistance of the brain to destructive influences (trauma, hypoxia), in reducing damage to the brain’s nerve cells (neurons). Noopept improves blood rheology, helps restore memory and other mental functions impaired due to injury, alcohol consumption, ischemia, and helps eliminate headaches, tachycardia, and insomnia.
Belarusian generics
Now on the market of the Belarusian manufacturer there are very few replacements of Noopept with cheaper analogues.
The best of them are presented in the table below:
| Name | Price, rub.) | Description |
| Neuro-norm | 25–190 | Another cheap but high-quality replacement for Noopept. Considering such a low cost, this drug has many advantages. |
Which include stimulation of blood circulation in the brain, stopping migraines and a therapeutic effect for disorders of the vestibular system.
Olatropil75–247 Thanks to the active substances piracetam and aminalone included in the drug, the drug stimulates the conductivity of synaptic structures without causing blood vessels to dilate.It has a number of minor side effects (anxiety, drowsiness, diarrhea).
Cinatropil60–145Gelatin capsules, which penetrate the body, are quickly absorbed into the walls of the stomach and reduce blood viscosity, which speeds up the reactions taking place in nerve cells.Excellent for partial memory loss and absent-minded attention. Has no acute side effects.
Evrizam115–180An effective substitute that promotes memory recovery, prevents fainting, suppresses tinnitus and combats anxiety.Patients who experience hemorrhage or exacerbations after major operations can take the drug only after consulting a doctor.
Indications for use
Noopept is also prescribed for elderly patients. This remedy can be used for disorders of cognitive functions of the brain . Thus, Noopept tablets are used in case of deterioration of memory, attention, or psycho-emotional disorders. Such disorders often appear when:
- recovery from traumatic brain injury, hypoxia, electroconvulsive or toxic effects;
- post-concussion syndrome (a pathological disorder that occurs after a traumatic brain injury, symptomatically expressed in deterioration of memory and attention, constant headache and dizziness, rapid loss of strength);
- encephalopathies of various types (cerebral vascular insufficiency);
- asthenic disorders;
- other conditions characterized by deterioration of intellectual activity to one degree or another.
How to take Noopept
At the first stage, this drug is taken in a daily dose of 20 mg, divided into two doses during the day, only in the morning or afternoon . However, doctors do not recommend taking the drug after 18:00. When using Noopept in the evening or at night, sleep disturbances may occur. If it is necessary to enhance the therapeutic effect, as well as if the drug is well tolerated, the dose is increased to 30 mg. The course of treatment lasts from 1.5 to 3 months. A repeated course is allowed no earlier than after 1 month.
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Interaction with other drugs
Interaction not established
with alcohol, sleeping pills and antihypertensive drugs and psychostimulant drugs.
These tablets should not be taken together with psycholeptics and sleeping pills. You should not combine the medicine with activated carbon and ancides, because the effectiveness of noopept may decrease.
The effect of the drug on driving vehicles and operating mechanical objects
There were no effects of the drug on the body while driving or operating any mechanical objects.
Noopept can be used in combination with other medications, but before combining the drug with other medications, you should consult your doctor. The drug is incompatible with alcohol, sleeping pills and some psycholeptics. Taking antacid medications reduces the effect of taking the drug.
Contraindications
It is not recommended to take Noopept for children under 18 years of age. This medicine is contraindicated in pregnant women. If it is necessary to treat with a drug during lactation, you should stop breastfeeding. You should avoid using Noopept tablets if you have hypersensitivity or an allergic reaction to certain components of the drug. Other contraindications include:
- lactase deficiency,
- lactose intolerance,
- glucose intolerance,
- acute disorders of the liver and kidneys.
Use during pregnancy and lactation period
After a series of special studies, scientists determined that no teratogenic or mutagenic effects were noted. However, there is no clinical experience of using these pills among pregnant women. In this regard, it is strongly not recommended for them.
At the same time, there is no accurate information about the safety of feeding a child breast milk during therapy. This is the reason for the ban. Admission is permitted only when breastfeeding is suspended.
Analogs
At the moment, there are many drugs similar to Noopept on the market. Each of the medications presented below has a similar effect, but they differ in the list of contraindications, possible side effects, and so on. You can choose the remedy that suits you among these:
- Lucetam - improves cognitive processes and mental performance without causing sedation. Stimulates blood circulation in the brain without vasodilating effects, improves communication between the two hemispheres of the brain. Lucetam restores and protects the brain after injury, hypoxia or intoxication.
- Nootropil is one of the most famous analogues of Noopept. A nootropic drug used to treat symptoms of memory disorders and cognitive impairment. Positively affects the emotional state of a person as a whole.
- Pantogam - has a nootropic, anticonvulsant effect, increases the brain's resistance to hypoxia (lack of oxygen) and the effects of toxins. It has a slight sedative effect and at the same time a stimulating effect.
- Picamilon - has an antioxidant, nootropic, tranquilizing effect, improves blood flow in brain tissue. Used in the treatment of depression, vegetative-vascular dystonia, alcoholism, traumatic brain injuries, migraines, etc.
- Piracetam - improves metabolic processes and blood circulation in brain tissue. It has an antioxidant, nootropic effect, restores cognitive functions of the brain (attention, memory, learning ability).
- Phenotropil has pronounced neuroprotective, antianorexic, and antiepileptic properties. Normalizes blood flow in the brain, improves cognitive functions, stimulates metabolism in brain tissue, having a beneficial effect on sleep, appetite, and mood.
- Glycine is a herbal preparation. The active substance is the amino acid glycine. This product has antioxidant, detoxification, and neuroprotective properties. It has a beneficial effect on sleep, stimulates memory, attention, improves metabolic processes and immunity of the whole body.
- Aminalon - the drug has a nootropic effect, improves brain performance, thinking, and memory. Contraindicated in case of hypersensitivity. Side effects include depression and insomnia.
- Cortexin has an antioxidant, nootropic, and neuroprotective effect. No side effects were found.
- Semax - has an antioxidant, antihypoxic, nootropic effect.
- Encephabol is a nootropic drug with a metabolic effect. Dispensed by prescription.
Analogues and cheap substitutes of Noopept
To find analogues, you first need to figure out what kind of drug Noopept is. The drug has a dual effect: The active substance Noopept, firstly, affects all three phases of memory: assimilation, storage and retrieval of information, and secondly, has a complex neuroprotective effect: improves the nutrition of neurons and protects brain cells from damage. The average cost of Noopept ranges from 340 to 370 rubles, the package contains 50 tablets. The medicine should be taken in the morning and afternoon (before 6 pm) one tablet at a time, so the package will last for almost a whole month of treatment.
Russian analogues and substitutes for Noopept
Of the domestic drugs similar to Noopept, the homeopathic remedy Divaz, produced by Materia Medica, is most often isolated. Divaza tablets are based on antibodies to brain-specific protein in multiple dilutions. The drug, according to the instructions, helps eliminate cognitive disorders, restore impaired functions of the nervous system, and stimulate mental activity. But the effectiveness of antibodies in such small dilutions has not been scientifically proven; today there is no evidence base and there is no data when it is possible to see and evaluate the effect of using this drug, so you should not completely trust homeopathic remedies.
One of the domestic analogues of Noopept can be considered the combination drug Vinpotropil, which includes piracetam and vinpocetine. Its manufacturer is Kanonpharma Production. Thanks to the active components, the drug helps to increase blood supply to the brain, its supply with oxygen and glucose, and restore communication between the two hemispheres.
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Unfortunately, the drug has a lot of side effects, including a negative effect on the cardiovascular system, central nervous system, digestive system, and sensory organs. They will be described in more detail below.
Foreign analogues and substitutes for Noopept
Analogs of European-made Noopept include tablets from the Bulgarian company Sopharma - Cinnarizine. The drug belongs to the group of calcium channel blockers, mainly affects the blood circulation of peripheral and cerebral vessels, improves the nutrition of tissues and organs. On the pharmaceutical market, Cinnarizine Sopharma can be purchased at a fairly low price, but in this case the low cost explains the equally low quality of production. The tablets have many undesirable effects, the most common of which are drowsiness, dyspeptic disorders, tremor, and weight gain.
Inexpensive drugs for improving brain function also include Lucetam, produced by the Hungarian company EGIC Pharmaceuticals. The tablets contain piracetam as an active component, thanks to the action of which memory and attention are restored, impaired as a result of toxic effects or insufficient oxygen supply to the brain.
And again we have to face a huge list of side effects, which, although they occur rarely, cast doubt on the safety of Lucetam.
Comparison of characteristics of Noopept analogues
Preparations based on piracetam (Vinpotropil, Lucetam), as well as Cinnarizine, although inexpensive, can aggravate the patient’s condition so that many side symptoms are added to the main disease.
Divaza is a homeopathic medicine. It has no side effects, but the effect of the drug can be attributed solely to the placebo effect. The effectiveness of Noopept, proven by repeated studies, is beyond any doubt.
Contraindications to the use of Noopept analogues
Contraindications to the use of Divaza: intolerance to the components, age under 18.
Contraindications to the use of Vinpotropil: intolerance to piracetam, vinpocetine and excipients, galactose intolerance, lactose deficiency, severe arrhythmia, severe ischemic heart disease, hemorrhagic stroke, renal and liver failure, pregnancy and lactation, age under 18.
Contraindications to the use of Cinnarizine: pregnancy and breastfeeding, age under 12.
Contraindications to the use of Lucetam: intolerance to piracetam, as well as other components of the drug, hemorrhagic stroke, pregnancy and lactation, renal failure. Caution is recommended when prescribing to patients with impaired hemostasis, during major surgical operations or to patients with symptoms of severe bleeding. Care should be taken when driving a car and operating machinery.
Side effects of Noopept analogues
Side effects of Divaza: local allergic reactions due to hypersensitivity.
Side effects of Vinpotropil: increased heart rate, changes in blood pressure, sleep disorders, dizziness, anxiety, increased excitability, impaired coordination of movements, deterioration of concentration, dyspeptic disorders.
Side effects of Cinnarizine: drowsiness, fatigue, extrapyramidal disorders, hand tremors, headache, intrahepatic cholestasis, dyspepsia, allergic reactions, weight gain.
Side effects of Lucetam: nausea, vomiting, diarrhea, abdominal and stomach pain, dizziness, headaches, balance problems, insomnia; from the psyche – confusion, agitation, anxiety, hallucinations; allergic reactions - itching, rashes, swelling.
Noopept price
The cost of the medicine is about 300 rubles . Below is the price of this drug in Moscow pharmacies. Check availability at specific pharmaceutical outlets:
| Pharmacy name | Price, rubles |
| Capital Pharmacy | 297 |
| Pharmacy Ponds" | 325 |
| Apteka.ru | 365 |
| Piluli.ru | 347 |
| Zdrav City | 332 |
| Rigla | 343 |
| Pharmacy Zhivika | 398 |
| Europharm | 380 |
