​The unique formula of Afobazole or the seven herbs of Novo-Passit? 6023 0

A comparative review of soothing herbal preparations Persen and Novo-Passit. Which is better in terms of composition, effectiveness and price? Novopassit or Persen - which is better?

Persen
Medicines based on herbal products are usually well tolerated and therefore have a large following. Clinical trial results indicate that the combination of valerian and lemon balm improves sleep disturbances to the same extent as benzodiazepines, but without significant sedation. Valerian as a single drug or in combination with other drugs can be prescribed not only to adults, but also to children.

In our pharmacies you can buy Novopassit and Persen, which contain this wonderful plant. Let's look at Novopassit or Persen - which helps better if you experience irritability, anxiety or suffer from insomnia.

There are contraindications, consult a specialist

Effect of Afobazole or Novo-Passit

Afobazole is a medicine for nerves and stress, based on the substance fabomotizol. The drug acts on nerve cells, performing protection and restoration functions.

There is a hackneyed phrase “nerve cells do not recover,” but now this expression is no longer relevant, and the drug Afobazol, which restores damaged cell structure, is proof of this. The drug has a neuroprotective effect, thanks to which the nervous system functions under stress in the same way as under normal conditions. Symptoms of stress - anxiety, tension, cognitive and autonomic disorders disappear 5-7 days after starting to take the drug, the maximum effect of Afobazole appears at the end of the fourth week of treatment. And with such effectiveness, Afobazole has a high safety profile.

Novo-Passit is a herbal preparation and consists of the herbs valerian, lemon balm, St. John's wort, hawthorn, passionflower and hops. The effect of Novo-Passit differs from the effect of Afobazol, first of all, in its short duration - the drug gently calms and relieves anxiety, but does not in any way affect the restoration of nerve cells and does not protect brain cells from subsequent stress. The drug has been on the Russian market for more than 20 years, and thanks to its herbal composition, it is suitable even for children over 12 years old.

Persen

This is a sedative drug with a calming and hypnotic effect . Contains a complex of plant components: valerian, lemon balm and peppermint.

Available in tablet form.

Indications for use:

  • Increased nervous excitability.
  • Nervous states accompanied by irritability and anger.
  • Insomnia and sleep disturbances (frequent waking up, etc.).

The drug is not prescribed to children under 12 years of age, pregnant and lactating women, patients with pathologies of the biliary tract, arterial hypertension, or allergies to the components of the drug. Since the tablets contain lactose and sucrose, the drug cannot be used by people with lactose and fructose intolerance, lactase and sucrase deficiency, or glucose-galactose malabsorption.

Available without a prescription.

Will I have to change my daily routine while taking Novo-Passit or Afobazol?

The most common factor that prevents a person from receiving treatment for stress is the fear of restrictions associated with taking medications.

Despite the herbal origin of the drug Novo-Passit, there are nuances that need to be paid attention to before use. It is not recommended to take Novo-Passit with other medications, since when interacting with foreign components, the effect of the drug may increase or decrease. The drug also enhances the effect of alcoholic beverages. Manufacturers recommend avoiding ultraviolet rays when treating with Novo-Passit, especially for patients with fair skin. Driving is also not recommended while taking the sedative Novo-Passit, as the drug causes drowsiness.

For drivers, the drug Afobazole is preferable, since, despite the fact that the drug relieves tension, anxiety and irritation, it does not cause drowsiness and does not affect the reaction. On the contrary, patients note an increase in performance. Afobazole can be taken with other medications. Afobazole may enhance the anticonvulsant effect of carbamazepine.

What is the difference between Persen and Novopassit?

Novopassit and Persen are sedatives that are sold without a prescription. Novopassit is available in the form of a solution in a bottle or packaged in small 10 ml bags. It is also available in tablet form.

Persen is a tablet. In addition, the line of this brand contains the drug Persen Night, which has a stronger effect due to the increased dosage of active ingredients. Produced in capsule form.

If Persen and Novopassit are compared in terms of the composition of the components, a more significant difference will be revealed.

Afobazole or Novo-Passit?

The advantage of both drugs is the absence of withdrawal syndrome and a high safety profile. But Afobazol and Novo-Passit can in no way be called analogues; the drugs perform completely different functions. Novo-Passit is of plant origin and soothes gently, but does not heal and does not have a long-term effect. Afobazole is a more effective medicine if you need not only momentary sedation, but also restoration of nerve cells.

Stress is the silent killer of our time. Put the responsibility for fighting this disease on medications and change the quality of your life!

Similarities

Both medications have a similar effect - they reduce nervous tension and restore calm . They are used for insomnia, increased nervous excitability and for conditions accompanied by irritability and aggression. A similar effect is due to the presence of two identical active ingredients - valerian and lemon balm.

Other similarities worth noting:

  • They improve sleep quality and speed up the process of falling asleep due to central nervous system depression.
  • Available in tablet form.
  • Available without a prescription.
  • Not assigned until age 12.

Efficacy of the drug

Each human body is an individual integral system of biochemical relationships. And the effectiveness of individual medications will be different for each patient. Afobazol will help some more, Novopassit will help others. No one can accurately predict what will be better. But with all this, it is this indicator that will be most important for most patients.

That is why, unfortunately, we find it difficult to give an unambiguous answer to this question. Everyone chooses for themselves from these medicines, taking into account the above arguments in favor of both medicines. We should only add - do not take these and other medications without the supervision of a doctor. After all, it is very rare that a person will be able to identify contraindications to the prescription of a particular drug, as well as determine the optimal dose of the drug.

Bottom line

Based on a detailed analysis of the two drugs, we can conclude that they are different in composition and therapeutic effect. The active substance Afobazole promotes the regeneration of damaged nerve cells. Novopassit triggers inhibition reactions in the brain, which leads to decreased attention.

Both drugs are well tolerated and have minimal contraindications. The advantage of Afobazole is the preservation of the therapeutic effect for 1-2 weeks after the end of the course of therapy.

It is better to choose the right drug for nervous disorders after consulting a doctor. Only a doctor will make the correct diagnosis and prescribe adequate therapy. Self-medication can worsen the patient's condition.

Patient reviews of the drugs

Since Afobazol or Novopassit are very popular anti-anxiety drugs, there are quite a lot of reviews about them left by patients on the Internet. Below are generalized reviews of these two drugs.

Patient reviews about Afobazole

There are extremely positive reviews about Afobazole, which are often based on the fact that the drug is very calming and relieves anxiety, without causing drowsiness.

Many patients note that already from 5-7 days they felt that panic and anxiety were receding, it became easier to bear stress, and the body adapted.

And the effect of Afobazole does not affect daily activity at all, the drug is well tolerated.

Patient reviews about Novopassit

There are many different reviews about Novopassit, mostly patients notice that the drug is calming, but at the same time affects their well-being; it is good to drink it at night, because it causes a slight decrease in blood pressure and drowsiness. Some people note that it causes stomach pain.

Which is better Afobazol or Novopassit?

These drugs are very different, of course, not only in composition, but also in their mechanism of action.

Afobazole helps the body fight stress, effectively reducing irritability, panic attacks, unreasonable anxiety and other neuropsychic reactions. Novopassit, one might say, inhibits the nervous system, which dulls the feeling of anxiety, but also other functions of the brain.

The use of Novopassit (like alcohol) significantly reduces concentration and activity. and Afobazole restores nerve cells, helps the body tolerate stress more easily, protecting the nervous system without causing the described side effects.

Therefore, when choosing Afobazole or Novopassit, it is important to consider how much your activity requires concentration.

What is more effective Afobazol or Novopassit?

These drugs are not analogues; they have a different mechanism of action and a different active ingredient.

Afobazole has proven its high effectiveness both in multiple clinical trials and in reviews of specialists, as well as patients who took this drug. In most cases, patients note that their condition has improved significantly with taking Afobazole, nervous tension, irritability have decreased and resistance to stress has increased.

Also, if Novopassit calms the nervous system, inhibiting it, then Afobazol restores the nervous system, helping the body cope with stress on its own, which is the best choice for a patient who cares about his health.

Having analyzed the effect of the two drugs, we can say that they are completely different in composition and mechanism of action. Afobazole contains a substance that restores nerve cells damaged by prolonged stress. Novopassit enhances inhibition processes in the brain, and because of this, concentration and attention decrease.

Afobazole is better tolerated, does not cause discomfort, and has a favorable safety profile. After discontinuation of the drug, the positive effect lasts for 1-2 weeks.

Source: https://narcofree.ru/ob_etom/afobazol-ili-novopassit-chto-luchshe

Side effects of Afobazole:

  • allergic manifestations;
  • bowel disorders - diarrhea;
  • nausea;
  • vomit.

Side effects of analogue drugs:

  • "Noofen" - drowsiness, nausea.
  • “Persen” – constipation, reactivity to the components of the composition.
  • “Novopassit” is a reaction from the muscular system in the form of cramps, weakness, as well as lethargy, fatigue, nausea, constipation, diarrhea, skin rashes.
  • "Glycine" - rarely allergic reactions.
  • "Adaptol" - rarely allergies, decreased blood pressure and body temperature.

Afobazole

Afobazole belongs to the group of light daytime tranquilizers (psychotropic tablets), which have an anxiolytic effect on the nervous system.

Application of the drug:

  • Reduces anxiety (tenot effect);
  • Strengthens concentration;
  • Reduces the symptoms of somatic diseases - asthmatic bronchitis, asthma (perspirant effect).

The advantage of using Afobazole, and not its analogues, is the absence of dependence (psychological or physical). Therefore, after discontinuation of the drug, “withdrawal syndrome” does not occur. The active substance of Afobazole is the synthetic compound marfolino ethyl thioethoxy benzimidazole dihydrochloride.

Thanks to this compound, the drug reduces tension and irritability without causing a sedative effect (muscle weakness, drowsiness, slowed reactions). On the contrary, reviews from patients who took Afobazole indicate that it has a good effect on concentration, helps restore memory and stimulates brain activity, facilitating a person’s rapid adaptation to a new team or new environment. This is how Afobazol differs from Novopassit, which, while relieving stress, has a sedative effect.

Persen or Novopassit - which is better in terms of richness of the composition?

Novopassit contains an extract of vegetative organs (leaves, rhizomes, roots, flowers) of the following plants:

  1. Valeriana officinalis - valerian,
  2. Hypericum perforatum - St. John's wort,
  3. Melissa officinalis - lemon balm,
  4. Passiflora incarnata - passion flower,
  5. Sambucus nigra - elderberry,
  6. Humulus lupulus - hops,
  7. Crataegus monogyna - hawthorn.

In addition, the medicine contains guaifenesin, a chemical derivative of propylene glycol and a substance that is extracted from the resin of the guaiac tree. In quantitative terms, the components in Novopassit are distributed as follows:

  • per tablet 0.2 g of guaifenesin and 0.157 g of plant dry extract,
  • in 1 ml of solution 0.04 g of guaifenesin and 0.077 g of plant liquid extract

Line of drugs "Novo-Passit"

The difference between Persen and Novopassit is a more modest composition of active ingredients. It contains only three ingredients:

  1. valerian,
  2. mint
  3. and Melissa.

Persen tablets 60 pcs. (new packaging)

There are also differences between representatives of the Persen brand. Persen Night contains 75 mg more.

Characteristics of plant components in Novopassit and Persen

It can be said that all the herbal components present in the Novopassit or Persen preparations have undergone the longest and most large-scale clinical trials, having been used in folk medicine in many countries for many centuries.

Nowadays, randomized clinical trials have confirmed the beneficial effects of valerian extracts on insomnia. 75 trial participants who received 0.6 g of valerian extract for 28 days experienced improved sleep quality. It was the same as in patients taking oxazepam, but with valerian there were no side effects characteristic of benzodiazepines.

The collection of herbs from which Novopassit is prepared has not only soothing properties due to the presence of valerian, passionflower, hops and lemon balm, but also general strengthening properties. St. John's wort is otherwise called a “remedy for 99 diseases”; elderberry is a medicinal plant with anti-inflammatory, bactericidal, astringent, diaphoretic and diuretic effects. Hawthorn is considered a “heart” medicine because it improves the supply of oxygen to the heart muscle, increases its energy balance, and reduces capillary fragility and permeability.

Guaifenesin has been used as an expectorant since the 50s of the last century. Now, for example, it is included in the drug Ascoril. However, its pronounced anxiolytic and muscle relaxant effect allows it to be used as a part of sedatives. In addition, guaifenesin can enhance the effect of hypnotics included in the drug.

The difference between Persen and Novopassit

For anxiety disorders, the question often arises about what is better to take: Persen or Novopassit, since both drugs have a similar effect and eliminate the effects of stress. These medications calm and normalize sleep.

For anxiety disorders, you can take Persen or Novopassit.

Comparison of Persen and Novopassit

Both drugs have similar effects on the body, but there are also significant differences.

Similarities

Both medications are used for anxiety disorders and sleep disorders.

What is the difference

Novopassit contains not only natural ingredients, but also an anxiolytic. This drug also differs from Persen in a more extensive list of adverse reactions.

What is more effective

Both drugs are effective in the treatment of neurosis-like diseases. However, Novopassit is considered more effective.

Which is stronger

Novopassit has a stronger effect on the central nervous system.

Which is cheaper?

Novopassit is cheaper than Persen. Its cost starts from 190 rubles. Price for Persen - from 240 rubles.

Which is better: Persen or Novopassit

The effectiveness of medications depends on the disease for which they are used.

For hyperhidrosis

To eliminate excessive sweating of psychosomatic etiology, it is best to use Novopassit.

For neurosis

For neurosis-like pathologies, both drugs are equally effective. If the disease is accompanied by increased anxiety and panic attacks, then it is better to take Novopassit.

During pregnancy

During pregnancy, both medications are contraindicated.

For insomnia

For mild insomnia, you can take Persen. If sleep disturbances have been present for a long time, then preference should be given to Novopassit.

Patients' opinions

Oleg, 47 years old, Tuymazy

I took both drugs at different times. I think Novopassit is more effective, although it often causes nausea. After a week of taking it, I felt that I became less nervous. I periodically repeat the course of treatment.

Larisa, 39 years old, Samara

I take Persen periodically for preventive purposes. Sometimes itching is caused by nervousness, and the medication perfectly eliminates such unpleasant symptoms. However, to notice the result, you need to take the medicine for at least a month.

Valentina, 63 years old, Moscow

For insomnia, I resort to taking Novopassit. The drug helps you fall asleep faster, although the effect does not appear immediately. Sometimes it is necessary to take the medicine for at least 1-2 weeks in order for sleep to normalize.

Reviews from doctors about Persen and Novopassit

Ksenia, 32 years old, general practitioner, Krasnodar

I consider Novopassit more effective and recommend it more often. However, it also has more side effects than Persen. It is especially important to pay attention to the fact that such a medicine can provoke a worsening of gastrointestinal diseases associated with high acidity. In other cases, it does its job perfectly.

Alla, 44 years old, therapist, Syzran

I often prescribe Persen to patients, because it is better tolerated and has a milder effect. However, it is not equally effective in all cases. For severe neuroses, Novopassit helps better.

Which is better - Novopassit or Persen

Each of the medications has an effective sedative effect on the body and helps eliminate disturbing symptoms.

Each of the medications has an effective sedative effect on the body and helps eliminate disturbing symptoms.

The choice of a therapeutic agent must be approached individually, based on the result and your internal feelings. Due to the difference in composition, drugs may be tolerated differently by the body and have different side effects.

Novopassit

Novopassit is a complex product that contains exclusively natural (herbal) ingredients. Prescribed for disorders of the nervous system.

Novopassit helps:

  • Restore mental balance;
  • Relieve anxiety;
  • Eliminate the problem of fears and nightmares;
  • Improve mood.

Novopassit is sold without a prescription, as it has a mild sedative effect and relieves emotional stress.

"Afobazol": analogues and substitutes. What is better - “Persen”, “Novopassit” or “Afobazol”?

Our body is subject to multiple influences from a huge number of negative factors, increased load, and stress. And as a result, we get emotional breakdowns, a feeling of constant anxiety and fear, aggravated by vicious addictions. Let's consider the drugs recommended by doctors in such situations - Afobazol, its analogues and substitutes.

Minor tranquilizer "Afobazol"

The selective anxiolytic “Afobazol” is an effective anti-anxiety drug developed by Russian pharmacologists, devoid of side effects characteristic of minor tranquilizers, and is highly effective. Taking it will not cause a negative effect on memory and concentration. Even long-term use of Afobazole does not lead to addiction. In addition, it has no withdrawal symptoms.

Along with suppressing anxiety, the drug has a slight stimulating effect. Reducing psychological instability caused by fears, forebodings, fears for no reason, insomnia, constant stress, has a stabilizing effect on the general condition of the body, including its physical component.

If you set a goal to find analogues and substitutes for Afobazole that will be cheaper, it is unlikely that you will be able to choose a drug with exactly the same active ingredient. These will be drugs that are similar in properties, but with a different mechanism of action, although they are related to sedatives. Let's list them:

  • "Adaptol" with the active ingredient mebicar. It is an anxiolytic drug with a moderate tranquilizer effect.
  • "Noofen" with the active substance phenibut. It has tranquilizer properties, reduces anxiety and fear, helps normalize sleep, stimulates physical condition and mental performance.
  • "Phenazepam" is a tranquilizer of the group of high-potency benzodiazepines. It has an anti-anxiety and calming effect, prevailing over other drugs.
  • "Glycine" with a non-essential amino acid. The drug calms the central nervous system, has a beneficial effect on sleep and the autonomic nervous system, and stimulates mental activity.
  • “Novopassit” is a combination drug consisting of guaifenesins and extracts of herbs, roots, leaves, flowers, and plant cones. The effect is sedative and anxiolytic.
  • “Persen” – the drug is based on extracts of medicinal herbs. Has a slight sedative effect.

Characteristics of Persen

Persen is also a remedy for panic conditions. This drug, created on the basis of herbs, is available in tablets (capsules), they contain the following active ingredients (dry extracts in 1 dose):

  • valerian root (50 mg);
  • peppermint leaf (25 mg);
  • lemon balm leaves (25 mg).

In case of irritability and increased nervous tension, take 2-3 tablets of Persen. 3 times a day, regardless of food intake.

Additional Ingredients:

  • MCC;
  • talc;
  • crospovidone;
  • starch;
  • silica;
  • magnesium stearate;
  • lactose.

In case of irritability and increased nervous tension, take 2-3 tablets. 3 times a day, regardless of food intake. And for insomnia, solid forms are shown in 1 piece. 1 hour before bedtime. The maximum daily dosage should not exceed 12 tablets. The classic course of treatment lasts 1 month; doctors do not recommend extending therapy for more than 2 months.

Side symptoms may occur against the background of antispasmodic action or overdose and are expressed as:

  • constipation;
  • allergies in the form of a rash (allergodermatosis);
  • bronchospasm;
  • heartburn (against the background of gastroesophageal reflux disease GERD);
  • drowsiness;
  • tremor of the limbs (rare);
  • dilated pupils.
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