Comparing Gliatilin and Cerakson | Determining the best

Instructions for use of Citicoline, dosage

Intravenous injections (IV) take at least 3 minutes; it is better to infuse the medicine dropwise at a rate of 40 to 60 drops per minute.
Intramuscular injection (IM) is used less frequently. After opening the ampoule, its contents must be used immediately. IM administration should be limited to a minimum, and repeated administration to the same site should be avoided.

In the acute period of traumatic brain injury or ischemic stroke, the standard dosage is 1000 mg of Citicoline every 12 hours. The duration of the course is at least 6 weeks. If the patient maintains normal swallowing function, it is recommended to switch to the oral form within 3-5 days after starting therapy.

During the recovery period, 500 mg to 2 grams per day are prescribed.

No dosage adjustment is required for elderly people.

For Parkinson's disease, 500 mg to 1000 mg per day is prescribed, with a treatment duration of up to a month (there may be several such courses per year).

Oral solution

Citicoline can be diluted in a small amount of water. It is recommended to drink before or during meals. Typically, 200 to 300 mg is prescribed 3 times a day.

The course of treatment is determined depending on the effectiveness of therapy and the patient’s condition.

Side effects

The instructions warn about the possibility of developing the following side effects when prescribing Citicoline:

Contraindications

Citicoline is contraindicated in the following cases:

• hypersensitivity to the drug;
• adolescence up to 18 years of age;
• increased tone of the parasympathetic nervous system.

The question of the advisability of use during pregnancy and lactation is decided during consultation with a doctor.

Overdose

Given the low toxicity of citicoline, cases of overdose have not been described, even when therapeutic doses are exceeded.

Interaction

Citicoline enhances the effect of levodopa.

Should not be administered concomitantly with medicinal products containing meclofenoxate.

Compatibility of Cerakson and Mexidol

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Ceraxon and Mexidol are nootropic drugs and are used to treat stroke and traumatic brain injury. Drugs can be prescribed together to improve their effects on the body.

When to take Cerakson

This is a nootropic drug. The active substance - citicoline - prevents the development of free radicals and eliminates tissue necrosis. In the acute stage of a stroke, the medicine reduces the number of affected brain cells.

If the skull is damaged, the length of the rehabilitation period is reduced. During hypoxia, the substance improves memory and concentration. The drug is prescribed for the treatment of motor neurological disorders. Release form: solution for internal use, solution for injection into a vein or muscle.

Why is Mexidol prescribed?

Mexidol is an antioxidant agent. The medicine has antihypoxic, nootropic, membrane-protective, and anticonvulsant properties. The product gives the body resistance to stress, damaging factors, and conditions such as shock and hypoxia. The drug is used to treat cerebrovascular disorders, ischemia, alcohol and drug intoxication.

The product improves metabolism and blood supply to the brain, normalizes blood circulation, reduces platelet aggregation and cholesterol concentration in the blood, and neutralizes toxins in pancreatitis. Release form: injection solution and tablets.

The combined effect of Ceraxon and Mexidol

Mexidol and Ceraxon can be used together, because they are complementary drugs. When treating cerebrovascular accidents, a neurologist may prescribe the use of these drugs simultaneously. When these medications are taken together, motor functions are normalized more quickly in patients with acute stroke than when each medication is used separately.

When patients recover from a stroke, they need medications that improve their emotional state. The combined use of these drugs reduces the manifestation of panic attacks, improves the adaptation process, and restores motor processes and thinking.

Indications for simultaneous use

Medicines are prescribed simultaneously for: circulatory disorders, ischemic stroke, traumatic brain injuries, vascular diseases, impaired skin regeneration, diabetes mellitus, and radiation therapy. When used together, Mexidol helps produce energy for the absorption of Ceraxon.

Contraindications:

• children under 18 years of age;
• intolerance to drug components;
• vagotonia.

How to take Cerakson and Mexidol together

Therapy must be prescribed by a doctor. Doctors recommend administering Mexidol and Ceraxon intravenously at the same time. The drugs are administered slowly over 3-5 minutes in the form of injections or 40-60 drops per minute when the drugs are administered as a dropper. It is better to administer medications intravenously than intramuscularly. For ischemic stroke and TBI, 1000 mg of the drug is prescribed every 12 hours.

Course - 6 weeks. In the post-stroke state, in the treatment of cognitive disorders and vascular diseases of the brain, take 500-2000 mg per day. Medicines are taken 5-10 ml 1-2 times a day. The exact doses and duration of therapy are prescribed by the doctor.

Side effects

Side effects:

• skin rashes;
• burning;
• headache;
• dizziness;
• anaphylactic shock;
• numbness of hands and feet;
• nausea;
• vomit;
• stool disorders;
• swelling;
• dyspnea.

Doctors

Solovyova Vera Vasilievna, neurologist

Mexidol and Ceraxon are often prescribed together to patients who have suffered an ischemic stroke. Medicines restore cell membranes and act on apoptosis. Medicines reduce the volume of necrotic brain tissue and normalize cholinergy.

Koroedov Viktor Fedorovich, neurologist: The simultaneous use of these drugs promotes effective action and reduces the period of rehabilitation of patients after TBI and stroke.

Patients

Olga Konstantinovna, 58 years old

After a stroke, my husband was prescribed the combined use of these medications. Thanks to this treatment, the rehabilitation period passed quickly.

Dmitry, 31 years old

After the concussion, I had a severe headache and dizziness. The neurologist prescribed these drugs. After the course of treatment, the negative symptoms disappeared and health was restored.

Applications and dosages

Due to the relatively high activity of citicoline, the determination of the appropriate therapeutic dosage of Ceraxon should only be carried out by an experienced physician based on the results of the examination of the patient. The same applies to the use of the product for the purposes of prevention and recovery.

Ceraxon injections are recommended to be administered slowly. Administration time varies from 3 to 5 minutes depending on the therapeutic dose

When administered intramuscularly, it is important to avoid injections in the same places. A drip method of infusion of medication is also possible.

In this case, the administration of Ceraxon should take place within 40-60 minutes.

For acute ischemic stroke or various brain injuries, it is recommended to take 1000 mg of citicoline twice a day with an interval of 12 hours. The treatment period should not last less than 6 weeks. If prescribed by a doctor, it is possible to switch to the oral form of Ceraxon 4-6 days after the start of treatment.

During the recovery period after a stroke and TBI, as well as for various cognitive and behavioral pathologies, it is recommended to take from 500 mg to 2000 mg of citicoline per day. The dosage should be divided into two doses. The amount of the substance is determined by the patient’s condition and the characteristics of the disease.

Side effects

Citicoline, which is the active component of Ceraxon, exhibits fairly high medicinal activity. In this regard, improper use of the drug entails the development of various side effects. However, if you follow the dosage regimen prescribed by your doctor, the likelihood of their occurrence is significantly reduced. The main side effects include:

• severe dizziness;
• acute headaches;
• attacks of hallucinations;
• difficulty breathing (dyspnea);
• vomiting and feeling of nausea;
• hypertension or hypotension;
• rapid heartbeat (may be accompanied by pain);
• anaphylactic shock (extremely rare);
• diarrhea;
• itchy allergic skin reactions;
• Quincke's edema (extremely rare).

The most common side effect after taking Ceraxon is a general painful state of the body, accompanied by chills and weakness.

Release form

Solution for intravenous and intramuscular administration, 500 mg/4 ml and 1000 mg/4 ml: in ampoules of colorless neutral glass (hydrolytic type I) with protective plastic tubes and white stripes for breaking the ampoules, 4 ml each; in PVC blister packaging 3 or 5 amp.; in a cardboard pack 1 package of 3 or 5 amps. or 2 packs of 5 amp.

Oral solution, 100 mg/ml: 30 ml of the drug in a colorless transparent glass bottle, sealed with a screw-on plastic cap that ensures first opening control. The bottle along with the dosing syringe is placed in a cardboard box with partitions inside.

Oral solution, 100 mg/ml: 10 ml of the drug in a bag made of a combined material (polyethylene terephthalate/polystyrene/aluminum foil/surlin polymer film). 6 or 10 sachets are placed in a cardboard box.

The medicine is intended for internal use and is available in several versions:

• syrup (capacity 30 ml);
• injection solution (in ampoules of 4 ml);
• tablets (pack of 20 pcs.);
• powder for preparing a suspension (a sachet containing 10 g of the drug; after dilution, 100 ml of the finished solution is obtained).

The cost of the drug differs depending on the purpose and volume of the container.

You can buy a pharmacological agent in Moscow at the price:

• syrup (30 ml, 100 mg) – 757 rubles;
• injections (5 ampoules of 4 ml, 500 mg) – 719 rubles;
• injections (5 ampoules of 4 ml, 1000 mg) – 1239 rubles;
• solution (10 sachets of 10 ml, 100 mg) – 1495 rub.

Finding out how much the drug costs is available in an online pharmacy or on an information and reference website, where, after entering your place of stay, nearby pharmacies that sell the pharmaceutical product are displayed.

pharmachologic effect

When taking Citicoline, the drug is virtually completely absorbed into the walls of the gastrointestinal tract; less than 1% of the drug taken is excreted from the body along with feces within five days after oral administration.

Experts note the same bioavailability regardless of the method of taking the drug; excretion is extremely slow and occurs mostly through the respiratory system or urine.

Studies have shown that five days after the start of the course, only about 16% of the doses of Citicoline taken are detected, this indicates that the remaining 84% of this drug is involved in the natural metabolic processes of the body.

In this case, the drug has the following effects on a person and his body:

1. Stimulation of biosynthesis and other biochemical processes associated with phospholipids in neuronal membranes. This effect has a positive effect on their functioning and the functioning of the receptors of the corresponding type.
2. Reduction of swelling of the brain, which occurs due to the stabilizing effect described above.
3. Reducing the duration of post-traumatic coma, which is often observed after suffering traumatic brain injuries.
4. Significant weakening of the pronounced symptoms of cerebral dysfunction, which can be caused by various pathological processes, for example, impaired blood circulation in the brain or previous traumatic brain injuries.
5. Elimination of the main symptoms of memory loss that occur after severe head injuries.
6. Improving the general condition of the patient and eliminating signs of disorders associated with the process of thinking, sensitivity or motor activity.
7. Reducing the manifestations of the main symptoms that occur when oxygen starvation of the brain or decreased blood supply to the brain.
8. Restoring the patient’s ability to perform actions aimed at self-care.
9. Increasing the level of emotional stability.
10. Creating conditions that can prevent the formation of free radicals.

Side effects

Frequency of side effects

Very rare ({amp}lt;1/10000 (including individual cases): allergic reactions (rash, itching, anaphylactic shock), headache, dizziness, feeling of heat, tremor, nausea, vomiting, diarrhea, hallucinations, swelling, shortness of breath, insomnia, agitation, loss of appetite, numbness in paralyzed limbs, changes in the activity of liver enzymes. In some cases, Ceraxon® can stimulate the parasympathetic system and also cause a short-term change in blood pressure.

If any of the side effects indicated in the instructions get worse, or any other side effects not listed in the instructions are noticed, you should inform your doctor.

The results of the studies indicate rare cases of adverse events (less than 1 case per 10,000 subjects).

Possible effects associated with exposure to citicoline include:

• sleep disturbance;
• dyspnea;
• loss of appetite;
• slight destabilization of the psycho-emotional background (apathy, agitation);
• numbness felt in areas of paralyzed limbs;
• loose stools;
• vomit;
• short-term change in blood pressure;
• decreased activity of liver enzymes.

If there is hypersensitivity to certain substances, the body reacts characteristic of an allergy.

If side effects increase and your health condition deteriorates sharply, you should seek qualified medical help.

Contraindications

This drug has a number of direct contraindications, in the presence of which its use is strictly prohibited, all of them are listed below:

1. Age under 18 years, since the specific effects of this drug on the child’s body are unknown.
2. Individual intolerance to individual components included in the drug.
3. Manifestation of an allergic reaction after starting treatment.
4. Vagatonia with pronounced symptoms.
5. Fructose intolerance is a contraindication only for the use of solutions; taking tablets is allowed.
6. Taking other pharmacological drugs that contain meclofenoxate.

Pregnancy and breastfeeding are not direct contraindications, but experts do not recommend taking Citicoline during these periods, since the degree of its effect on the fetus or the characteristics of excretion along with milk have been poorly studied.

However, in some cases, such therapy is required, but only after receiving appropriate permission from the obstetrician and when the pregnancy is less than six months old.

Cerakson analogues - list of cheap Russian drugs

Ceraxon is a popular effective drug from the group of nootropics. The drug is prescribed for the treatment of various neurological disorders associated with degenerative processes in brain structures or vascular damage. The drug is produced in 2 dosage forms:

• solution for intravenous and intramuscular administration;
• solution for oral administration.

The active ingredient of the drug, citicoline, has a wide spectrum of action. With regular use, it has a positive effect on brain cells - preventing their death, restoring damaged membranes. This helps reduce the severity of neurological symptoms due to brain damage due to stroke, TBI and other factors.

Prices of the drug and its main analogues, average in Russia

Ceraxon is a high-quality medicine that is produced in Spain. It is freely available, but is quite expensive. On pharmacy shelves you can find other, no less effective, but cheaper analogues of the drug.

The table shows the main analogues of Ceraxon in terms of composition and mechanism of action, as well as their prices in different pharmacies in Russian cities.

Name of the drug and release formPharmacy, cityCost in rubles

TOP 10 analogues of the drug No-shpa in tablets and ampoules

Effective analogues of the active substance

Ceraxon contains the active ingredient citicoline. In addition to the Spanish drug, you can buy its structural analogues in pharmacies - Recognan, Neupilept or Ceresil.

Recognan

The nootropic drug is available in the form of a solution for intravenous and intramuscular administration. Its manufacturer is the Italian pharmaceutical company ALFASIGMA. Indications for use are:

• traumatic brain injuries and their consequences;
• cerebral infarction or stroke and their consequences;
• cerebral hemorrhages;
• mild cognitive impairment (for example, early stage senile dementia);
• behavioral disorders.

Most often, the drug is prescribed as part of complex therapy. It is not used to treat pregnant and lactating women, children under 18 years of age, or in the presence of intolerance to the components that make up the medicine.

Naypilept

A structural analogue of domestic production is available in the form of a solution for intravenous and intramuscular administration of 500 and 1000 mg of the active substance. The medicine is indicated as part of a complex treatment of the acute and recovery period of ischemic stroke, the consequences of traumatic brain injury, as well as degenerative and vascular diseases of the brain.

It is forbidden to use the drug if you are intolerant of its components, vagotonia, children under adulthood and pregnant women. The most likely side effects are:

• allergic skin and anaphylactic reactions;
• headaches and dizziness;
• swelling;
• problems with the digestive system (nausea, vomiting, diarrhea, loss of appetite);
• numbness in paralyzed limbs.

Neurological disorders are also possible - insomnia, tremors, agitation, hallucinations.

Ceresil

This is another domestic nootropic drug with the active substance citicoline. It is produced by Canonpharma CJSC. Release form: solution for intramuscular and intravenous administration. The product has identical indications, contraindications, and side effects as previous drugs based on citicoline.

TOP 10 cheap analogues of the drug Flixonase in the form of a spray

Substitutes for therapeutic effect

In some cases, medications are required that have a different active substance (for example, if you are intolerant), but have a similar therapeutic effect.

Vinpocetine

The action of a medicine based on vinpocetine is aimed at improving cerebral blood flow and metabolism, as well as normalizing blood viscosity. The spectrum of action of the product is very wide, in particular:

• stroke;
• TBI;
• cerebral atherosclerosis;
• encephalopathy;
• spasm of cerebral vessels;
• vascular dementia;
• motor and cognitive disorders;
• thrombosis of eye vessels, glaucoma, retinal changes;
• hearing impairments of various nature;
• vasovegetative disorders associated with menopause.

This medication is prohibited for use in the presence of heart problems - coronary artery disease, severe arrhythmia, as well as in children under 18 years of age; pregnant and breastfeeding women.

Piracetam

Piracetam, which is the basis of the drug of the same name, is a nootropic substance that is a cyclic derivative of gamma-aminobutyric acid (GABA).

Its main effect is to improve connections between the hemispheres of the brain and synaptic transmission in neocortical structures, as well as improve cerebral blood flow.

It is used for the symptomatic treatment of intellectual-mnestic disorders (if there is no diagnosis of dementia) and for myoclonus (involuntary muscle contractions).

Contraindications for its use are:

• intolerance to piracetam and pyrrolidone derivatives;
• hemorrhagic stroke;
• Huntington's chorea;
• severe chronic renal failure;
• age up to 3 years;
• severe hemorrhagic disorders.

Noobut

This is a psychostimulant and notropic drug based on phenibut. Available in the form of tablets for oral administration of 100 or 250 mg of the active ingredient. The main advantage is its mild action and lack of pronounced toxicity. It can be prescribed to children to treat stuttering, urinary incontinence, and nervous tics.

For adults, the medicine helps cope with insomnia, emotional lability, stress, nervousness, and asthenia. The drug is also prescribed to prevent motion sickness and to eliminate withdrawal symptoms.

Glycine

Glycine is an amino acid that is produced by the human body. To compensate for its deficiency, a synthesized analogue is used. When consuming the substance, there is an improvement in metabolism in the brain.

Glycine has antidepressant, antitoxic, antioxidant and sedative effects. It is prescribed to improve intellectual and thinking abilities, eliminate neuroses, sleep problems, and also as part of a comprehensive treatment of alcoholism.

Cortexin

A drug based on polypeptides from the cerebral cortex of cattle is classified as a neurostimulant. It is available in the form of a lyophilized powder, from which a solution for injection is prepared. The main actions are nootropic, neuroprotective, antioxidant.

Cortexin is prescribed as an adjuvant for:

• stroke and TBI;
• asthenia;
• encephalopathy;
• epilepsy;
• cerebral palsy;
• delayed speech and psychomotor development in children.

Mebicar

Mebicar is a psychostimulant drug based on tetramethyltetraazabicyclooctanedione.

It has moderate tranquilizing activity, therefore it is prescribed to eliminate restlessness, anxiety, feelings of fear, as well as excessive irritability. This remedy is often used to treat childhood hyperactivity.

Another indication is complex therapy for tobacco addiction (as a means of relieving irritability syndrome when quitting smoking).

Ceraxon is a popular nootropic drug that is prescribed to eliminate the consequences of stroke and TBI. It has many analogues - both structural and with a similar therapeutic effect. You should select a nootropic together with your doctor, taking into account the characteristics of a particular patient.

Source: https://Pilyule.com/analogi/cerakson/

Opinions of adult patients about the medicine

"Cerakson" - a solution, reviews of which we will give below, deserves positive responses from women and men who have taken this drug. Thus, those adult patients who took this medicine orally note that it greatly helped them recover from a stroke, and also forget what panic attacks are. Many patients stopped having headaches after they began treatment with Ceraxon. This medication deservedly receives a clear A from patients. Therefore, if the doctor prescribed the drug “Ceraxon” for oral administration for traumatic brain injury, encephalopathy and other problems, then you should trust a specialist and be treated with this medicine.

Cerakson

Active substance:

Citicoline*

Pharmgroup:

Nootropics

Average price in pharmacies

Description and composition

Sodium citicoline is used as the main active element of the drug Ceraxon. The dosage of the substance in one unit of the product is determined by the release form. The range of auxiliary elements also differs.

• Tablet form: talc, titanium dioxide, castor oil and magnesium stearate, ammonium methacrylate copolymer, microcrystalline cellulose.
• Oral solution: glycerin, citric acid, glycerinformal, purified water, sorbitol, sodium citrate and saccharin, food coloring, berry essence, methylparaben, nipazole.
• Injection solution: water for injection, sodium hydroxide or hydrochloric acid.

Compound

The active component of the drug is citicoline sodium, which has the following properties:

• has a stabilizing effect on the membrane;
• reduces cerebral edema;
• weakens the severe symptoms of cerebral dysfunction resulting from injury or acute circulatory disorders in the brain;
• helps reduce the level of amnesia, etc.

Depending on the form of release of the drug, the main substance is supplemented with auxiliary components that improve the absorption of the drug by the body.

The list of components used by the manufacturer includes:

• sorbitol;
• methyl parahydroxybenzoate;
• glycerol;
• sodium citrate dihydrate;
• propyl parahydroxybenzoate;
• sodium saccharinate;
• potassium sorbate;
• strawberry flavor (strawberry essence 1487-S-Lucta);
• citric acid (50% solution);
• purified water.

The effect of the drug in relation to children

"Ceraxon" - a solution for oral administration - receives mostly positive reviews from parents. So, doctors often prescribe this drug to babies who at birth had problems such as hypoxia, enlargement of parts of the brain, and abnormal brain function. After the children were treated with this medication, the result pleasantly surprised the parents. After treatment with Ceraxon, the children’s motor skills improved (for example, rolling over, standing up, sitting), and muscle tone returned to normal. Older children who were treated with this medication experienced improved memory and concentration, boys and girls became more diligent and attentive.

And the drug “Cerakson” helped many parents, whose children until a certain age (for example, at 4-5 years old) could not yet speak, to develop the speech of their offspring. After treatment with this remedy, mothers could not recognize their children: boys and girls began to babble so that it was difficult to stop them. In general, this drug is truly effective, and this is proven by numerous reviews from people on various forums.

In addition to the undoubted positive result, parents like the convenient form of release of the medicine.

The pleasant strawberry taste of the medicine is another advantage, because which child would want to drink a tasteless medicine? But here the manufacturer was concerned about the kids and invented a special form of the drug in the form of a sweet solution for children.

CERAKSON: analogues, generics, synonyms, cheap analogues

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from 15 UAH

PIRACETAM

Piracetam is used as a means of improving memory, concentration, mental performance, and also as a regulator of higher mental activity. It is indicated as an effective remedy for depression accompanied by lethargy, low mood and decreased overall performance.

from 201 UAH

QUATTREX

The drug Quattrex is prescribed for stress, to increase intellectual activity, improve sleep quality, and combat insomnia problems. For children, Quatrex is prescribed for the treatment of stuttering and nervous tics. Neuroses, Memory, Insomnia, Improved sleep

from 133 UAH

VAZAVITAL

Herbal preparation Vasavital Prescribed to adults for the prevention and complex treatment of: dyscirculatory encephalopathy with disturbances of attention, memory, perception, decreased intellectual ability; in the early stages of Alzheimer's disease; neurosensory disorders: cochleovestibular syndrome (tinnitus, hypoacusis, dizziness); diabetic retinopathy; arteriopathy of the lower extremities (pain when walking, trophic disorders); Raynaud's syndrome. Neuralgia, Memory, Prevention, Diabetes

from 171 UAH

CAVINGTON

The vasodilating effect of the drug Cavinton is associated with a direct relaxing effect on smooth muscles. The drug enhances the metabolism (exchange) of norepinephrine and serotonin in brain tissue, reduces pathologically increased blood viscosity, and helps increase the plasticity of red blood cells. Neuroses, Memory, Cardiovascular drugs, Medicines

from 256 UAH

PHESAM

The drug Phezam is used for cerebrovascular insufficiency; intoxication; other diseases of the central nervous system, accompanied by a decrease in intellectual and mental functions; psychoorganic syndrome with a predominance of signs of asthenia and adynamia, asthenic syndrome; labyrinthopathy, Meniere's syndrome; lagging intellectual development in children; for the purpose of preventing migraine and kinetosis. Nervous system, Memory, Medicines

from 655 UAH

CEREBROLYSIN

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OLATROPIL

The drug Olatropil has a positive effect on the processes of metabolism and blood circulation in the brain, stimulates redox processes and improves regional blood flow in ischemic areas of the brain, increases the energy potential of neurocytes with the participation of ATP and adenylate cyclase. Psychotropic drugs, Nootropic drugs

from 350 UAH

PANTOCALCIN

Pantocalcin is a nootropic drug that has cerebroprotective, anticonvulsant and antidysuric effects, helps improve metabolism in cells and tissues, and prevents the development of hypoxia. Nootropic drugs, cerebral palsy

from 93 UAH

LUTSETS

The drug Lucetam is a nootropic drug used in the symptomatic treatment of intellectual-mnestic disorders in the absence of an established diagnosis of dementia.

Semax 1%

Semax drops 1% are a nootropic drug used in the acute period of ischemic stroke. It has cerebroprotective, antihypoxic, nootropic, antioxidant effects. Stroke, Nootropic drugs

from 180 UAH

Cavinton forte

The drug Cavinton Forte has a complex mechanism of therapeutic action associated with a beneficial effect on blood circulation and brain metabolism, as well as on the rheological properties of blood.

from 163 UAH

MEMOTROPIL

The drug Memotropil is a nootropic drug used in the symptomatic treatment of intellectual-mnestic disorders in the absence of an established diagnosis of dementia.

GLYCINE-VIS

Glycine-VIS is a complex drug, the components of which have a positive effect on the activation of brain cells, improving memory, and slowing down the aging process of the brain.

CEREBRIL

The drug Cerebril is a nootropic drug that facilitates the learning process, social rehabilitation of patients, and eliminates neurological and mental complications.

from 307 UAH

PRAMISTAR

The drug Pramistar is a nootropic drug used for decreased ability to concentrate and memory disorders of a degenerative or vascular nature, especially in the elderly.

GLYCINE-CANON

The drug Glycine-Canon has glycinergic, antioxidant and antitoxic effects; regulates the activity of glutamate receptors, thereby reducing psycho-emotional stress, aggressiveness and conflict

WINNER-LF

Winner-LF treats mental and neurological symptoms of cerebrovascular disorders of various origins (after a cerebral stroke, brain injury or sclerotic manifestations), such as memory impairment, movement disorders, dizziness, headache; intermittent insufficiency and spasm of cerebral vessels, ischemic brain damage, cerebral atherosclerosis. Dizziness, Headache, Cerebral circulation, Atherosclerosis

PYRATROPIL

The drug Piratropil is a nootropic drug that has a protective effect against brain damage caused by hypoxia, intoxication, and electric shock. Improves integrative brain activity.

from 1950 UAH

FENOTROPIL

Phenotropil has a direct activating effect on the integrative activity of the brain, promotes memory consolidation, improves concentration and mental activity, facilitates the learning process, increases the resistance of brain tissue to hypoxia and toxic effects, has an anticonvulsant effect and anxiolytic activity, regulates the processes of activation and inhibition of the central nervous system. systems, improves mood. Diseases of the central nervous system, metabolic disorders in the brain

Source: https://www.medcentre.com.ua/analogi/tserakson.html

Pharmacological group

Based on the type of therapeutic action, the drug Ceraxon belongs to the group of nootropic drugs with a wide spectrum of effects. Among the main effects provided by the active component of the product are:

• improving the quality of cholinergic synapses in the brain;
• inhibition of the activity of phospholipase enzymes;
• restoration of damaged cell membranes;
• reducing the duration of being in a comatose state and the frequency of various neurological manifestations;
• preventing the formation of free radicals;
• a significant reduction in the area of ​​damage to brain tissue in a state of acute stroke;
• helps speed up the recovery period.

In the case of the development of chronic hypoxia, Ceraxon has a positive effect on various cognitive pathologies. These include:

• memory impairment;
• apathy and lack of initiative;
• difficulty performing daily self-care activities.

During therapy with Ceraxon, not only the ability to remember information improves, but also concentration, performance and the general state of brain activity.

Pharmacodynamics

Citicoline, being a precursor of key ultrastructural components of the cell membrane (mainly phospholipids), has a wide spectrum of action - it promotes the restoration of damaged cell membranes, inhibits the action of phospholipases, prevents the excessive formation of free radicals, and also prevents cell death by affecting the mechanisms of apoptosis.

In the acute period of stroke, citicoline reduces the volume of brain tissue damage and improves cholinergic transmission. In case of TBI, it reduces the duration of post-traumatic coma and the severity of neurological symptoms, in addition, it helps to reduce the duration of the recovery period.

In chronic cerebral hypoxia, citicoline is effective in the treatment of cognitive disorders such as memory impairment, lack of initiative, and difficulties in performing daily activities and self-care. Increases the level of attention and consciousness, and also reduces the manifestation of amnesia.

Citicoline is effective in the treatment of sensory and motor neurological disorders of degenerative and vascular etiology.

Indications for use

As already mentioned, taking the drug “Citicoline” is allowed only as prescribed by the attending physician.

The main indications for its use in general therapy are:

1. Received traumatic brain injuries, and this remedy can be prescribed both in the acute period and during rehabilitation.
2. The rehabilitation period after strokes, which were accompanied by hemorrhages or, conversely, a significant decrease in the required blood supply.
3. The most difficult periods during a stroke are when the flow of the required amount of arterial blood is stopped. If this indication is present, Citicoline is not an independent drug, but only part of a complex therapy aimed at restoring the patient’s condition.
4. Decreased mental activity, partial or complete loss of memory, disorders in the patient’s behavior if they are caused by lesions of the brain vessels or various degenerative diseases.

About the drug

Ceraxon, like its analogues, is widely used in medical practice for complex therapy and during the recovery period in patients with various forms of multiple sclerosis, when its purpose is to reduce the foci of affected cells and slow down, less often completely stop, their destruction. The drug reduces cerebral edema, which helps to level out cognitive impairment and behavioral disorders.

In pediatric practice it is used less frequently, for serious indications:

• severe intrauterine hypoxia;
• consequences of traumatic brain injury;
• cerebrovascular accident;
• various forms of cerebral palsy (as part of complex treatment).

Ceraxon has analogs that are similar in action and differ in price. But, nevertheless, generic nootropics use different active ingredients, which should be prescribed by a doctor.

Analogues of the drug Cerakson

There are no complete analogues. The group of nootropic drugs includes:

1. Escotropile.
2. Ampasse.
3. Cereton.
4. Phenotropil.
5. Pyriditol.
6. Pantogam active.
7. Gliatilin.
8. Glutamic acid.
9. Tenoten.
10. Picanoil.
11. Glycine.
12. Intellan.
13. Ginkyo.
14. Neuromet.
15. Cebrilyzin.
16. Stamin.
17. Pantogam.
18. Gamma-aminobutyric acid.
19. Nootropil.
20. Idebenone.
21. Aminalon.
22. Encephabol.
23. Delecite.
24. Glycerylphosphorylcholine hydrate.
25. Cerepro.
26. Cerebrolysate.
27. Gleazer.
28. Pyramem.
29. Gammalon.
30. Gopantam.
31. Piracetam.
32. Choline alfoscerate.
33. Calcium hopantenate.
34. Mexipridol.
35. Nooclerin.
36. Noocetam.
37. Cerebrolysin.
38. Meclofenoxate hydrochloride.
39. Noben.
40. Cortexin for children.
41. Semax.
42. Pramistar.
43. Pyratropil.
44. Pikogam.
45. Demanol.
46. Cortexin.
47. Minisem.
48. Cerutile.
49. Hopantenic acid.
50. Lutsetam.
51. Pantocalcin.
52. Cerebril.
53. Amylonosar.
54. Memotropil.
55. Pirabene.
56. Picamilon.
57. Noopept.
58. Ginos.
59. Cerebramin.
60. Mexiprim.
61. Nootobril.
62. Energy ball.
63. Holitylin.
64. Phenibut.
65. Mexicofin.
66. Tenoten for children.

Mechanism of action

Neurometabolic effects mean improved nutrition of brain tissue, improved absorption and use of glucose, normalization of cell membranes in brain cells.

The nootropic effect consists of stimulating brain functions, including mental and cognitive functions - speech, memory, learning and memorization. It also implies normalization of the emotional state if the patient suffers from unreasonable mood swings.

The drug is able to exhibit an antioxidant effect, prevent foci of necrosis and ischemia - areas of the brain that are deprived of adequate oxygen supply as a result of poor blood circulation.

The medicine is also used in the treatment of stroke, as it is able to reduce the volume of damaged cells and tissues, as well as stimulate the transmission of nerve impulses.

When using the drug for rehabilitation after a traumatic brain injury, it stimulates the normalization of memory, speech, memorization, and thought processes. Reduces the likelihood and duration of coma after traumatic brain injury, and also eliminates the symptoms of neuralgia.

Release forms

The drug is known under the trade name Citicoline Novo, which is available in the form of injection solutions. One bottle contains four milliliters of solution.

The active ingredient of the drug is available in the form of citicoline syrup, which can be sold under the trade name Ceraxon. The well-known form of citicoline is in a sachet, ten milliliters for oral administration.

Another dosage form is film-coated tablets, ten or twenty pieces per package. Ten milliliters of solution are dispensed into the sachet.

Compound

The drug in tablet form may contain pure citicoline or citicoline sodium, depending on the trade name, which does not change the effect of the drug in the body.
Additional components include castor oil, talc and cellulose. The oral sachet contains 100 mg per milliliter of citicoline, as well as sorbitol, flavoring and citric acid.

Recognan

Recognan is a substitute for Ceraxon containing the active ingredient Citicoline. Cheaper than previous drugs: its price ranges from 400 to 600 rubles per 30 ml of syrup for oral administration. The medicine is also available in a solution for administration of 4 ml. Produced by the Moscow Endocrine Plant in Russia and the Alpha Wassermann company in Italy.

A dosage of 1000 mg of Recognan, an analogue of Ceraxon, twice a day is sufficient for positive dynamics in the treatment of conditions that are accompanied by impaired coordination, attention, and disorders of consciousness. Stimulation of cerebral vessels occurs due to an increase in the level of choline in the blood plasma. In the structures of brain cells, active penetration of the substance into the mitochondrial and cytoplasmic membranes occurs.

Somazin

Synonyms for the drug Ceraxon include Somazina, produced by FERRER Internacional, SA (Spain). The medicine contains 500 mg of Citicoline in the form of an injection solution for injection into the muscle or intravenously. Somazina is not the cheapest analogue of Ceraxon: the cost of the drug is more than 1,500 rubles per bottle of 5 ampoules of 4 ml.

Citicoline, which is part of the composition, has a positive effect on the treatment of various cerebral pathologies accompanied by:

• amnesia;
• reduced mental performance;
• apathy;
• degenerative lesions of cerebral vessels.

Somazina is an analogue of Ceraxon in tablets. In this dosage form, the drug is prescribed as a sedative that improves adaptation to new conditions and eliminates the build-up of sleep and wakefulness.

Comparison of safety of Cerepr and Cerakson

The safety of a drug includes many factors.

At the same time, in Cereprus it is quite similar to Cerakson. It is important where the drug is metabolized: drugs are excreted from the body either unchanged or in the form of products of their biochemical transformations. Metabolism occurs spontaneously, but most often involves major organs such as the liver, kidneys, lungs, skin, brain and others. When assessing metabolism in Cerepr, as well as in Ceracson, we look at which organ is the metabolizing organ and how critical the effect on it is.

The risk-benefit ratio is when the prescription of a drug is undesirable, but justified under certain conditions and circumstances, with the obligatory observance of caution in use. At the same time, Cerepra does not have any risks when used, just like Cerakson.

Also, when calculating safety, it is taken into account whether only allergic reactions occur or possible dysfunction of the main organs. In other matters, as well as the reversibility of the consequences of using Cerepr and Cerakson.

special instructions

During the treatment period, care should be taken when performing potentially hazardous activities that require special attention and quick reactions (driving a car and other vehicles, working with moving mechanisms, working as a dispatcher and operator, etc.).

Oral solution (optional).

In the cold, a small amount of crystals may form due to temporary partial crystallization of the preservative. With further storage under recommended conditions, the crystals dissolve within several months. The presence of crystals does not affect the quality of the drug.

Comparison of addiction in Cereprus and Ceraxon

Like safety, addiction also involves many factors that must be considered when evaluating a drug.

So, the totality of the values ​​of such parameters as “o syndrome” in Cereprus is quite similar to the similar values ​​in Cerakson. Withdrawal syndrome is a pathological condition that occurs after the cessation of intake of addictive or dependent substances into the body. And resistance is understood as initial immunity to a drug; in this it differs from addiction, when immunity to a drug develops over a certain period of time. The presence of resistance can only be stated if an attempt has been made to increase the dose of the drug to the maximum possible. At the same time, in Cereprus the meaning of the “syndrome” is quite small, however, the same as in Cerakson.

Comparison of the effectiveness of Cerepr and Cerakson

Ceraxon is more effective than Cerepra - this means that the ability of the drug substance to provide the maximum possible effect is different.
For example, if the therapeutic effect of Cerakson is more pronounced, then it is impossible to achieve this effect with Cerepra even in large doses.

Also, the speed of therapy is an indicator of the speed of the therapeutic action; Cerakson and Cerepra are also different, as is bioavailability - the amount of a drug substance reaching the place of its action in the body. The higher the bioavailability, the less it will be lost during absorption and use by the body.

Use during pregnancy and breastfeeding

There are no sufficient data on the use of citicoline in pregnant women. Although animal studies have not revealed any negative effects, during pregnancy the drug Ceraxon® is prescribed only in cases where the expected benefit to the mother outweighs the potential risk to the fetus.

When prescribing Ceraxon® during lactation, women should stop breastfeeding, since there is no data on the excretion of citicoline in human milk.