CORTEXIN AND MEXIDOL: can they be taken simultaneously (compatibility)

Cortexin: purpose, indications, dosage

The nootropic, neuroprotective drug Cortexin is made on the basis of an animal product - the cerebral cortex of calves . Action of the product:

1. Improves the metabolism of neurons in the central and peripheral nervous system.
2. Improves brain function.
3. Actively used to improve memory.
4. Positively affects patient learning.
5. Reduces the toxic effect when using psychotropic drugs (for seriously ill patients).

The drug penetrates the BBB due to its natural origin. Relaxes the vascular system damaged by ischemia, resulting in improved blood flow.

Cortexin is available in ampoules in the form of a white powder. Before use, the powder is diluted in 2 ml of water for injection, and to reduce pain, the drug can be diluted with novocaine or icecaine in the proportion of 1 ml of water to 1 ml of novocaine .

It is administered intramuscularly, slowly. The injection must be given in the first half of the day, since Cortexin stimulates the nervous system.

The medicine is well tolerated and does not cause side effects. An allergic reaction may rarely occur to novocaine, so young children are advised to dissolve Cortexin with water for injection.

Treatment is carried out in a course of 10 injections . Repeat as necessary after 3-6 months .

The drug must be used exclusively as prescribed by the attending physician. Available from pharmacies without a prescription.

Treatment of children

Can Mexidol and Cortexin be used for children? Only the appropriate doctor should prescribe the use of two drugs. If the positive effect from their use exceeds the possible health risk, then their use will be permitted. But in any case, you need to consult with specialists.

Application and doses are prescribed only by a doctor. It is worth noting that the medicine Cortexin for children is available in small dosages. But the dose of Mexidol must be prescribed by the doctor. It is important to take the medication only in the prescribed dosage; if it is exceeded, the child may experience unpleasant health problems.

It is imperative to remember that before using any medicine you must carefully study the instructions. Any drug has contraindications under which they should not be taken. Regarding the two medications under consideration, they should not be used during pregnancy and lactation, as well as for problems with the liver and kidneys.

Mexidol: action, indications for use

Mexidol also refers to nootropic drugs used in the treatment of patients with impaired cerebral blood supply. It is actively used in the treatment of the consequences of stroke, traumatic brain injury, epilepsy, and cerebral palsy. The effect of the drug is antihypoxic, nootropic, and anticonvulsant.

Mexidol helps:

1. Establish metabolic processes in the brain.
2. Relieves him from oxygen starvation.
3. Prevents the occurrence of seizures.
4. Improve patient self-control.
5. Has a beneficial effect on thinking and speech.

Excellently increases the permeability of brain cell membranes and neutralizes the negative effects of cholesterol. Strengthening blood vessels and improving brain nutrition contributes to rapid recovery after ischemia. The state of the nervous system is regulated and actively restored thanks to Mexidol.

The drug is available in ampoules and capsules. It is administered intramuscularly once a day in the morning.

What is the difference between Cortexin or Mexidol

Pharmacological properties

Mexidol is an antioxidant agent, that is, it blocks the formation of free radicals toxic to nervous tissue. These substances are formed when there is a low supply of oxygen to brain cells (neurons) and destroy their membranes, causing rapid death. The drug also works as an antihypoxant, improving the delivery and use of oxygen by neurons, has nootropic activity - improves thinking, memory, cognitive abilities; reduces seizures, suppresses anxiety, increases the resistance of neurons to adverse factors.

Cortexin is primarily a nootropic. It consists of small protein particles that normalize the production of various chemical compounds in the brain: mediators, growth factors, amino acids. All of them have multidirectional effects: some stimulate, others inhibit the functioning of neurons. The medicine allows you to achieve their optimal ratio, which is necessary for the full functioning of the brain. Thanks to this, cortexin protects and promotes the restoration of damaged neurons, regulates metabolic processes, suppresses seizures, and enhances stress resistance.

Indications

• strokes – death of a part of the brain due to insufficient blood flow;
• injuries (bruises of varying severity, concussions) of the brain;
• acute and chronic ischemia (lack of blood supply) in the brain and heart muscle;
• neuro-circulatory dystonia is a disruption of the autonomic nervous system, affecting internal organs, which is manifested by changes in blood pressure, rapid heartbeat, spasms in the intestines, and attacks of uncontrollable fear;
• overdose of drugs for the treatment of mental illness - antipsychotics;
• mental and motor agitation against the background of withdrawal syndrome (withdrawal syndrome) in alcoholics;
• restlessness and anxiety, stressful conditions;
• purulent-inflammatory diseases of the pancreas and peritoneum;
• initial mild disorders of thinking and memory.

• brain diseases of various origins - vascular, infectious, traumatic;
• disorders of higher brain functions: memory, attention, thinking, speech;
• epilepsy – paroxysmal convulsions;
• asthenia – exhaustion of the nervous system, increased fatigue, mood instability;
• cardiopsychoneurosis;
• in children: learning difficulties, delayed speech and psychomotor development; cerebral palsy (CP).

Contraindications

• severe renal and hepatic pathologies;
• age not exceeding 18 years;
• pregnancy and lactation;
• hypersensitivity to the drug.

• the period of bearing a child and feeding him breast milk;
• individual intolerance to the drug.

Side effects

• nausea;
• dry mouth;
• skin allergies;
• increased drowsiness.

Release form and price

Mexidol

• tablets 125 mg, 30 pcs. — 281 rub.;
• tablets 125 mg, 50 pcs. — 387 rub.;
• solution 5% 2 ml, 10 amp. — 504 rub.;
• solution 5% 5 ml, 20 amp. — 1654 rub.;
• solution 5% 2 ml, 50 amp. - 2004;
• solution 5% 5 ml, 50 ampoules - 4710 rubles;

Cortexin

• bottles of 5 mg, 3 ml, 10 pcs. – 836 rub.;
• bottles of 10 mg, 5 ml, 10 pcs. – 1271 rub.

Cortexin and Mexidol - what do they have in common?

The drugs are united by a common group – nootropics. Both medications:

• Affects the improvement of brain function.
• Activate cell metabolism.
• Have a therapeutic effect in the form of increased performance;
• Helps improve memory.
• Restore blood vessels after injuries and damage.

Since the drugs Mexidol and Cortexin are nootropics, they have a stimulating effect on the nervous system . The action of drugs activates metabolic processes and makes the human brain work actively. Both are used in the morning.

Cortexin and Mexidol complement each other in their action. The compatibility of the drugs is high. Both have a positive effect on various types of ischemia, are well accepted and act quickly.

Treatment of children

Prescribing drugs for children

If treatment is necessary for a child, the question may also arise: Are Cortexin and Mexidol allowed to be injected together? This decision is made solely by the attending physician. If the benefit of taking these drugs together outweighs the risk, then such a combination is allowed. In any case, you should always consult several specialists. But it is worth noting that in children who have cerebral palsy, the combined use of medications improves cognitive function.

As for the daily dose for children, it should immediately be noted that for children Cortexin is initially produced in a small dosage, which is what you should buy. This also applies to Mexidol. You should never change the dosage yourself, otherwise you can only harm the baby. Children weighing less than twenty kilograms are administered 0.5 mg per kilogram of weight. And for everyone else - ten milligrams once a day.

Before using any medicine, be sure to read the instructions and consult your doctor. After all, like any medicine, these medications also have certain contraindications. If you follow these simple rules, a positive result will be achieved.

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Difference between drugs

But quite often neurologists prescribe both drugs at the same time, why if the effect is approximately the same?

The fact is that the active ingredients of the drugs Cortexin and Mexidol are different. If Mexidol is a development based on chemical elements, then Cortexin is a natural extract from the brain cells of domestic animals, whose body is as close as possible in structure to humans.

Natural elements are more easily and quickly accepted by the damaged body, the action occurs more efficiently and quickly. Mexidol strengthens this effect. At the molecular level, chemicals are better perceived by the body. You can compare this process to the construction of a building. If there is a foundation, then brick and concrete together build a strong wall. This is how Cortexin interacts with Mexidol and restores the damaged nervous system as quickly as possible.

It is important to use drugs in childhood. Cortexin is well tolerated and accepted by children even in the first year of life, so it is actively used in cases of damage to the nervous system due to birth trauma and hemorrhages. The drug helps many children with speech and mental development delays. The safety and effective action of Cortexin made it possible to compensate for damage in many children at the stage of active growth and development.

Mexidol is used more in older patients. Then the body is more susceptible to chemical drugs, and the body’s rejection of the drug in the form of side effects is less likely. Often prescribed after injuries or coronary heart disease.

Mexidol and Cortexin injections at the same time reviews

Cortexin is a multicomponent drug. It contains protein elements, biologically active and vitamin complexes. Cortexin components help restore nerve fibers and normalize central nervous system function.

The pharmacological feature of this drug is the ability to penetrate the blood-brain barrier due to its low molecular weight. This distinguishes Cortexin from other drugs for the treatment of neurological disorders that cause circulatory problems in the brain.

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The mechanism of action of Cortexin is that the amino acid balance is restored. As a result, memory improves, convulsive reactions are suppressed, the aging process of nerve cells is inhibited, and the patient’s mental ability increases. Such pharmacological properties of Cortexin allow it to be used in several areas.

Indications

The medicine is used in the following cases:

1. Rehabilitation after hemorrhagic stroke (to restore speech, vision, memory).
2. Symptomatic treatment of diseases of the nervous system caused by pathological microorganisms.
3. Pathologies of the retina and optic nerve.
4. Lumbosacral radiculitis.
   Cortexin is prescribed for the symptomatic treatment of diseases of the nervous system caused by pathological microorganisms.

Cortexin is prescribed to patients of all age categories.

The drug is released as a solution for injection in 5 ml bottles.

Application Feature

When prescribing Cortexini Mexidol medications at the same time, it is important to understand that one drug is used first - Cortexin, and then Mexidol is administered. Thus, the first prepares the body’s sensitivity to the active substances.

In addition, you can track the occurrence of side effects. Cortexin, as a rule, does not cause discomfort, since it is a more natural and natural substance, while Mexidol can cause a reaction in the body in the form of nausea, increased blood pressure, and dizziness.

For a one-time dose, it is better to choose the following form of administration: Cortexin injections and Mexidol tablets. Although Mexidol is available in the form of a solution for intramuscular administration, in case of joint use it is better to limit oneself to one intramuscular injection - Cortexin.

Medicine and healthComment

Side effects

When administering drugs, the following side effects may occur:

• decreased blood pressure, headache, dizziness;
• nausea and vomiting, dry mouth, loose stools;
• allergic reactions in the form of skin rashes, urticaria, Quincke's edema.

In old age, in the absence of contraindications, Cortexin is administered in standard doses.